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IPR021419 is a Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain.
<p>The overall function of the full-length Med25 is efficiently to coordinate the transcriptional activation of RAR/RXR (retinoic acid receptor/retinoic X receptor) in higher eukaryotic cells. Human Med25 consists of several domains with different binding properties, the N-terminal, VWA domain which is this one, an SD2 domain from residues 229-381, a PTOV(B) or ACID domain from 395-545, an SD2 domain from residues 564-645 and a C-terminal NR box-containing domain (646-650) from 646-747. This VWA or von Willebrand factor type A domain when bound to RAR and the histone acetyltransferase CBP is responsible for recruiting Med1 to the rest of the Mediator complex [[cite:PUB00053503]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: mediator of RNA polymerase II transcription subunit 25-like [Fragaria vesca subsp]. vesca] gi|470130018|ref|XP_004300904.1| | 7 | ||
| – | PREDICTED: mediator of RNA polymerase II transcription subunit 25-like [Fragaria vesca subsp]. vesca] gi|470130018|ref|XP_004300904.1| | 7 | ||
| – | PREDICTED: mediator of RNA polymerase II transcription subunit 25-like isoform X1 [Cicer arietinum] gi|502164870|ref|XP_004513303.1| | 8 | ||
| – | PREDICTED: mediator of RNA polymerase II transcription subunit 25-like isoform X1 [Cicer arietinum] gi|502164870|ref|XP_004513303.1| | 8 | ||
| – | PREDICTED: mediator of RNA polymerase II transcription subunit 25-like isoform X1 [Cicer arietinum] gi|502164870|ref|XP_004513303.1| | 7 | ||
| – | Mediator of RNA polymerase II transcription subunit 25; TAIR: AT1G25540.1 phytochrome and flowering time regulatory protein (PFT1); Swiss-Prot: sp|Q7XYY2|MED25_ARATH Mediator of RNA polymerase II transcription subunit 25; TrEMBL-Plants: tr|A0A151RZ52|A0A151RZ52_CAJCA Mediator of RNA polymerase II transcription subunit 25; Found in the gene: LotjaGi2g1v0200700 | 7 | ||
| – | Mediator of RNA polymerase II transcription subunit 25; TAIR: AT1G25540.1 phytochrome and flowering time regulatory protein (PFT1); Swiss-Prot: sp|Q7XYY2|MED25_ARATH Mediator of RNA polymerase II transcription subunit 25; TrEMBL-Plants: tr|A0A151RZ52|A0A151RZ52_CAJCA Mediator of RNA polymerase II transcription subunit 25; Found in the gene: LotjaGi2g1v0200700 | 7 | ||
| – | Mediator of RNA polymerase II transcription subunit 25; TAIR: AT1G25540.1 phytochrome and flowering time regulatory protein (PFT1); Swiss-Prot: sp|Q7XYY2|MED25_ARATH Mediator of RNA polymerase II transcription subunit 25; TrEMBL-Plants: tr|A0A151RZ52|A0A151RZ52_CAJCA Mediator of RNA polymerase II transcription subunit 25; Found in the gene: LotjaGi2g1v0200700 | 7 | ||
| – | Mediator of RNA polymerase II transcription subunit 25; TAIR: AT1G25540.1 phytochrome and flowering time regulatory protein (PFT1); Swiss-Prot: sp|Q7XYY2|MED25_ARATH Mediator of RNA polymerase II transcription subunit 25; TrEMBL-Plants: tr|A0A151RZ52|A0A151RZ52_CAJCA Mediator of RNA polymerase II transcription subunit 25; Found in the gene: LotjaGi2g1v0200800 | 7 | ||
| – | Mediator of RNA polymerase II transcription subunit 25; TAIR: AT1G25540.1 phytochrome and flowering time regulatory protein (PFT1); Swiss-Prot: sp|Q7XYY2|MED25_ARATH Mediator of RNA polymerase II transcription subunit 25; TrEMBL-Plants: tr|A0A151RZ52|A0A151RZ52_CAJCA Mediator of RNA polymerase II transcription subunit 25; Found in the gene: LotjaGi2g1v0200800 | 7 | ||
| – | Mediator of RNA polymerase II transcription subunit 25; TAIR: AT1G25540.1 phytochrome and flowering time regulatory protein (PFT1); Swiss-Prot: sp|Q7XYY2|MED25_ARATH Mediator of RNA polymerase II transcription subunit 25; TrEMBL-Plants: tr|A0A151RZ52|A0A151RZ52_CAJCA Mediator of RNA polymerase II transcription subunit 25; Found in the gene: LotjaGi2g1v0200800 | 7 | ||
| – | Mediator of RNA polymerase II transcription subunit 25-like protein; TAIR: AT1G25540.1 phytochrome and flowering time regulatory protein (PFT1); Swiss-Prot: sp|Q7XYY2|MED25_ARATH Mediator of RNA polymerase II transcription subunit 25; TrEMBL-Plants: tr|A0A072UMI0|A0A072UMI0_MEDTR Mediator complex subunit 25 von willebrand factor type A protein; Found in the gene: LotjaGi2g1v0212100 | 5 | ||
| – | Mediator of RNA polymerase II transcription subunit 25-like protein; TAIR: AT1G25540.1 phytochrome and flowering time regulatory protein (PFT1); Swiss-Prot: sp|Q7XYY2|MED25_ARATH Mediator of RNA polymerase II transcription subunit 25; TrEMBL-Plants: tr|A0A072UMI0|A0A072UMI0_MEDTR Mediator complex subunit 25 von willebrand factor type A protein; Found in the gene: LotjaGi2g1v0212100 | 5 | ||
| – | Mediator of RNA polymerase II transcription subunit 25-like protein; TAIR: AT1G25540.1 phytochrome and flowering time regulatory protein (PFT1); Swiss-Prot: sp|Q7XYY2|MED25_ARATH Mediator of RNA polymerase II transcription subunit 25; TrEMBL-Plants: tr|A0A072UMI0|A0A072UMI0_MEDTR Mediator complex subunit 25 von willebrand factor type A protein; Found in the gene: LotjaGi2g1v0212100 | 5 | ||
| – | Mediator of RNA polymerase II transcription subunit 25; TAIR: AT1G25540.1 phytochrome and flowering time regulatory protein (PFT1); Swiss-Prot: sp|Q7XYY2|MED25_ARATH Mediator of RNA polymerase II transcription subunit 25; TrEMBL-Plants: tr|A0A151RZ52|A0A151RZ52_CAJCA Mediator of RNA polymerase II transcription subunit 25; Found in the gene: LotjaGi2g1v0280300 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 6.67 |