Description

IPR022343 is a GCR1-cAMP receptor.

<p>Heterotrimeric G protein-mediated signalling via activated 7-transmembrane (7TM) serpentine receptors is well known in a range of organisms, but evidence for the existence of this pathway in plants has been elusive. Over the years, however, evidence that G proteins are involved in signal transduction in plants has been accumulating, leading several researchers to seek plant 7TM receptors.</p> <p>The first tangible evidence for a plant 7TM receptor came through an analysis of the expresssed sequence tag database, dbEST. This revealed an Arabidopsis thaliana gene (GCR1) that encodes a protein with 7 predicted TM domains, and other features characteristic of known 7TM receptors [[cite:PUB00053651], [cite:PUB00053652]]. The amino acid sequence of GCR1, however, is unusual in that it shows similarity to receptors from three different 7TM families [[cite:PUB00053651], [cite:PUB00053652]], sharing greatest levels of similarity with the Dictyostelium cAMP receptors.</p> <p>It has been suggested that the cAMP receptors coordinate aggregation of individual cells into a multicellular organism, and regulate the expression of a large number of developmentally-regulated genes [[cite:PUB00005114], [cite:PUB00001912], [cite:PUB00001913]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 6

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: