Description

IPR024176 is a Citrate synthase, bacterial-type.

<p>Citrate synthase [ec:2.3.3.1] is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle, namely the conversion of oxaloacetate and acetyl-coenzyme A into citrate and coenzyme A. This reaction is important for energy generation and for carbon assimilation. The reaction proceeds via a non-covalently bound citryl-coenzyme A intermediate in a 2-step process (aldol-Claisen condensation followed by the hydrolysis of citryl-CoA).</p> <p>This entry represents types I and II citrate synthase enzymes, as well as the related enzymes 2-methylcitrate synthase. 2-methylcitrate ([ec:2.3.3.5]) synthase catalyses the conversion of oxaloacetate and propanoyl-CoA into (2R,3S)-2-hydroxybutane-1,2,3-tricarboxylate and coenzyme A (CoA). This enzyme is induced during bacterial growth on propionate, while type II hexameric citrate synthase is constitutive [[cite:PUB00013490]]. This entry contains citrate synthases from bacteria and some eukaryotic (peroxisomal), and also an enzyme from Bacillus subtilis (citrate/2-methylcitrate synthase) that acts as both a citrate synthase and a methylcitrate synthase [[cite:PUB00033360], [cite:PUB00090961]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 1

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: