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IPR025742

Source: InterPro

Description

IPR025742 is a Cleavage stimulation factor subunit 2, hinge domain.

<p>The hinge domain of cleavage stimulation factor subunit 2 proteins, CSTF2, is necessary for binding to the subunit CstF-77 within the polyadenylation complex and subsequent nuclear localisation. This suggests that nuclear import of a pre-formed CSTF complex is an essential step in polyadenylation. Accurate and efficient polyadenylation is essential for transcriptional termination, nuclear export, translation, and stability of eukaryotic mRNAs. CSTF2 is an important regulatory subunit of the polyadenylation complex [[cite:PUB00057933]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
Lj4g3v3099310.1
– PREDICTED: cleavage stimulation factor subunit 2-like isoform X2 [Cicer arietinum] gi|502163524|ref|XP_004512866.1|
Domains
7
Lj5g3v1888380.1
– PREDICTED: cleavage stimulation factor subunit 2 tau variant-like [Cicer arietinum] gi|502118796|ref|XP_004496403.1|
Domains
15
LotjaGi4g1v0453000.2
– Cleavage stimulation factor subunit 2; TAIR: AT1G73840.1 hydroxyproline-rich glycoprotein family protein; Swiss-Prot: sp|Q9M9G6|CTF64_ARATH Cleavage stimulating factor 64; TrEMBL-Plants: tr|C6T790|C6T790_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi4g1v0453000
Domains
8
LotjaGi5g1v0284300.1
– RNA-binding protein; TAIR: AT1G71800.1 cleavage stimulating factor 64; Swiss-Prot: sp|Q9M9G6|CTF64_ARATH Cleavage stimulating factor 64; TrEMBL-Plants: tr|I1NH73|I1NH73_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0284300
Domains
18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 25.00