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IPR026896

Description

IPR026896 is a Transcription termination and cleavage factor, C-terminal domain.

<p>The C-terminal section of cleavage stimulation and termination factor CstF-64 (CSTF2) and its yeast orthologue Rna15 form a discreet structure that is crucial for mRNA 3'-end processing [[cite:PUB00041903]]. This domain interacts with Pcf11 and possibly PC4, thus linking CSTF2 to transcription, transcriptional termination, and cell growth [[cite:PUB00057933]].</p> <p>Proteins containing this domain also include Pti1 protein from budding yeast. Pti1 is an essential component of CPF (cleavage and polyadenylation factor) involved in 3' end formation of snoRNA and mRNA [[cite:PUB00075465]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process MRNA 3'-end processing Any process involved in forming the mature 3' end of an mRNA molecule.

Associated Lotus transcripts 8

Transcript Name Description Predicted domains Domain count
Proline-rich protein precursor [Glycine max] gi|351722127|ref|NP_001237489.1| 3
Proline-rich protein precursor [Glycine max] gi|351722127|ref|NP_001237489.1| 10
PREDICTED: cleavage stimulation factor subunit 2-like isoform X2 [Cicer arietinum] gi|502163524|ref|XP_004512866.1| 7
PREDICTED: cleavage stimulation factor subunit 2 tau variant-like [Cicer arietinum] gi|502118796|ref|XP_004496403.1| 15
Cleavage stimulation factor subunit 2; TAIR: AT1G73840.1 hydroxyproline-rich glycoprotein family protein; Swiss-Prot: sp|Q9M9G6|CTF64_ARATH Cleavage stimulating factor 64; TrEMBL-Plants: tr|C6T790|C6T790_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi4g1v0448400 6
Cleavage stimulation factor subunit 2; TAIR: AT1G73840.1 hydroxyproline-rich glycoprotein family protein; Swiss-Prot: sp|Q9M9G6|CTF64_ARATH Cleavage stimulating factor 64; TrEMBL-Plants: tr|C6T790|C6T790_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi4g1v0453000 11
Cleavage stimulation factor subunit 2; TAIR: AT1G73840.1 hydroxyproline-rich glycoprotein family protein; Swiss-Prot: sp|Q9M9G6|CTF64_ARATH Cleavage stimulating factor 64; TrEMBL-Plants: tr|C6T790|C6T790_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi4g1v0453000 8
RNA-binding protein; TAIR: AT1G71800.1 cleavage stimulating factor 64; Swiss-Prot: sp|Q9M9G6|CTF64_ARATH Cleavage stimulating factor 64; TrEMBL-Plants: tr|I1NH73|I1NH73_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0284300 18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 12.50