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IPR027040 is a 26S proteasome non-ATPase regulatory subunit 4.
<p>The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively [[cite:PUB00062757]].</p> <p>This family consists of the RC subunit S5A or non-ATPase regulatory subunit 4 (PSMD4, also known as Rpn10). Rpn10 binds and presumably selects ubiquitin-conjugates for destruction [[cite:PUB00062754], [cite:PUB00062756]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein. | ||
| Cellular component | Proteasome regulatory particle, base subcomplex | The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: 26S proteasome non-ATPase regulatory subunit 4-like isoform 1 [Glycine max] gi|356559272|ref|XP_003547924.1| | 15 | ||
| – | PREDICTED: 26S proteasome non-ATPase regulatory subunit 4-like [Glycine max] gi|356496629|ref|XP_003517168.1| | 12 | ||
| – | PREDICTED: 26S proteasome non-ATPase regulatory subunit 4-like [Glycine max] gi|356496629|ref|XP_003517168.1| | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 33.33 |