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IPR028005 is a N-acetyltransferase ESCO, zinc-finger.
<p>This entry represents the zinc-inger domain of the acetyl-transferase ESCO. N-acetyltransferase ESCO1 and ESCO2 are required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. They act by mediating the acetylation of cohesin component SMC3 [[cite:PUB00060906]]. They feature a conserved C-terminal domain consisting of a H2C2 zinc finger motif and an acetyltransferase domain ([interpro:IPR028009]), while the diverse N-terminal domain is involved in chromosome binding and could target these proteins to different chromosome structures [[cite:PUB00060905]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: N-acetyltransferase ESCO2-like isoform X1 [Cicer arietinum] gi|502088238|ref|XP_004488777.1| | 12 | ||
| – | N-acetyltransferase ESCO2-like protein; TAIR: AT4G31400.1 protein CTF7; Swiss-Prot: sp|A7UL74|CTF7_ARATH Protein CHROMOSOME TRANSMISSION FIDELITY 7; TrEMBL-Plants: tr|A0A1J7H5Z1|A0A1J7H5Z1_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0736600 | 11 | ||
| – | N-acetyltransferase ESCO2-like protein; TAIR: AT4G31400.1 protein CTF7; Swiss-Prot: sp|A7UL74|CTF7_ARATH Protein CHROMOSOME TRANSMISSION FIDELITY 7; TrEMBL-Plants: tr|A0A1J7H5Z1|A0A1J7H5Z1_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0736600 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 33.33 |