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IPR032566 is a Aprataxin, C2HE/C2H2/C2HC zinc finger.
<p>This is an unusual zinc-binding domain found in fungi, plants and metazoa. It is often found at the C terminus of HIT-domain-containing proteins ([interpro:IPR001310]). In fungi the fourth ligand is a Glu, in plants it is Cys and in metazoans it is usually a His. The fourth ligand is often mutated in neurogenerative disease-states [[cite:PUB00076524]].</p> <p>This domain can be found in Aprataxin, a DNA-binding protein involved in single-strand and double-strand DNA break repair, and base excision repair [[cite:PUB00070310], [cite:PUB00070311], [cite:PUB00070312]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: transcription factor bHLH140-like [Glycine max] gi|356496191|ref|XP_003516953.1| | 28 | ||
– | Transcription factor bHLH140; TAIR: AT5G01310.1 APRATAXIN-like protein; Swiss-Prot: sp|Q9M041|BH140_ARATH Transcription factor bHLH140; TrEMBL-Plants: tr|K7K399|K7K399_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0162600 | 29 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 50.00 |