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IPR032678 is a tRNA synthetases class I, catalytic domain.
<p>This entry represents the catalytic (Rossmann-fold) domain found in cysteinyl tRNA synthetases [[cite:PUB00076739]] which is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.</p> <p>Cysteine-tRNA ligase (also known as cysteinyl-tRNA synthetase) ([ec:6.1.1.16]) is an alpha monomer and belongs to class Ia [[cite:PUB00056788]]. It aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. It is highly specific despite not possessing the amino acid editing activity characteristic of many other tRNA ligases [[cite:PUB00028887], [cite:PUB00079872], [cite:PUB00079873], [cite:PUB00007363], [cite:PUB00079874], [cite:PUB00079875], [cite:PUB00079876], [cite:PUB00079877], [cite:PUB00079878], [cite:PUB00000723], [cite:PUB00007191], [cite:PUB00079800]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: cysteinyl-tRNA synthetase-like [Glycine max] gi|356515262|ref|XP_003526320.1| | 15 | ||
– | PREDICTED: cysteinyl-tRNA synthetase-like [Glycine max] gi|356515262|ref|XP_003526320.1| | 17 | ||
– | PREDICTED: cysteine--tRNA ligase-like isoform X2 [Cicer arietinum] gi|502132428|ref|XP_004501355.1| | 16 | ||
– | PREDICTED: cysteinyl-tRNA synthetase-like [Glycine max] gi|356575566|ref|XP_003555910.1| | 14 | ||
– | PREDICTED: cysteinyl-tRNA synthetase-like [Glycine max] gi|356575566|ref|XP_003555910.1| | 11 | ||
– | Cysteine--tRNA ligase; TAIR: AT2G31170.1 Cysteinyl-tRNA synthetase, class Ia family protein; Swiss-Prot: sp|F4IPY2|SYCM_ARATH Cysteine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|A0A0B2PHM9|A0A0B2PHM9_GLYSO Cysteine--tRNA ligase; Found in the gene: LotjaGi1g1v0381500 | 17 | ||
– | Cysteine--tRNA ligase; TAIR: AT2G31170.1 Cysteinyl-tRNA synthetase, class Ia family protein; Swiss-Prot: sp|F4IPY2|SYCM_ARATH Cysteine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|K7KTG7|K7KTG7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0381500 | 20 | ||
– | Cysteine--tRNA ligase; TAIR: AT2G31170.1 Cysteinyl-tRNA synthetase, class Ia family protein; Swiss-Prot: sp|F4IPY2|SYCM_ARATH Cysteine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|A0A0B2PHM9|A0A0B2PHM9_GLYSO Cysteine--tRNA ligase; Found in the gene: LotjaGi1g1v0381500 | 15 | ||
– | Cysteine--tRNA ligase; TAIR: AT5G38830.1 Cysteinyl-tRNA synthetase, class Ia family protein; Swiss-Prot: sp|B3LFA4|SYCC2_ARATH Cysteine--tRNA ligase 2, cytoplasmic; TrEMBL-Plants: tr|A0A151U7E6|A0A151U7E6_CAJCA Cysteinyl-tRNA synthetase; Found in the gene: LotjaGi5g1v0338000 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd00672 | CDD | 1 | 11.11 |