Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR032678

Description

IPR032678 is a tRNA synthetases class I, catalytic domain.

<p>This entry represents the catalytic (Rossmann-fold) domain found in cysteinyl tRNA synthetases [[cite:PUB00076739]] which is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.</p> <p>Cysteine-tRNA ligase (also known as cysteinyl-tRNA synthetase) ([ec:6.1.1.16]) is an alpha monomer and belongs to class Ia [[cite:PUB00056788]]. It aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. It is highly specific despite not possessing the amino acid editing activity characteristic of many other tRNA ligases [[cite:PUB00028887], [cite:PUB00079872], [cite:PUB00079873], [cite:PUB00007363], [cite:PUB00079874], [cite:PUB00079875], [cite:PUB00079876], [cite:PUB00079877], [cite:PUB00079878], [cite:PUB00000723], [cite:PUB00007191], [cite:PUB00079800]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 9

Transcript Name Description Predicted domains Domain count
PREDICTED: cysteinyl-tRNA synthetase-like [Glycine max] gi|356515262|ref|XP_003526320.1| 15
PREDICTED: cysteinyl-tRNA synthetase-like [Glycine max] gi|356515262|ref|XP_003526320.1| 17
PREDICTED: cysteine--tRNA ligase-like isoform X2 [Cicer arietinum] gi|502132428|ref|XP_004501355.1| 16
PREDICTED: cysteinyl-tRNA synthetase-like [Glycine max] gi|356575566|ref|XP_003555910.1| 14
PREDICTED: cysteinyl-tRNA synthetase-like [Glycine max] gi|356575566|ref|XP_003555910.1| 11
Cysteine--tRNA ligase; TAIR: AT2G31170.1 Cysteinyl-tRNA synthetase, class Ia family protein; Swiss-Prot: sp|F4IPY2|SYCM_ARATH Cysteine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|A0A0B2PHM9|A0A0B2PHM9_GLYSO Cysteine--tRNA ligase; Found in the gene: LotjaGi1g1v0381500 17
Cysteine--tRNA ligase; TAIR: AT2G31170.1 Cysteinyl-tRNA synthetase, class Ia family protein; Swiss-Prot: sp|F4IPY2|SYCM_ARATH Cysteine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|K7KTG7|K7KTG7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0381500 20
Cysteine--tRNA ligase; TAIR: AT2G31170.1 Cysteinyl-tRNA synthetase, class Ia family protein; Swiss-Prot: sp|F4IPY2|SYCM_ARATH Cysteine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr|A0A0B2PHM9|A0A0B2PHM9_GLYSO Cysteine--tRNA ligase; Found in the gene: LotjaGi1g1v0381500 15
Cysteine--tRNA ligase; TAIR: AT5G38830.1 Cysteinyl-tRNA synthetase, class Ia family protein; Swiss-Prot: sp|B3LFA4|SYCC2_ARATH Cysteine--tRNA ligase 2, cytoplasmic; TrEMBL-Plants: tr|A0A151U7E6|A0A151U7E6_CAJCA Cysteinyl-tRNA synthetase; Found in the gene: LotjaGi5g1v0338000 16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00672 CDD 1 11.11