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IPR033100

Source: InterPro

Description

IPR033100 is a Exosome complex component RRP45.

<p>Rrp45, also known as EXOSC9, is a core component of the RNA exosome complex which participates in a multitude of cellular RNA processing and degradation events [[cite:PUB00045433]].</p> <p>The conserved core of the exosome complex, the major eukaryotic 3' --> 5' exonuclease, consists of nine subunits that form a ring similar to the phosphorolytic bacterial PNPase and archaeal exosome [[cite:PUB00045434], [cite:PUB00035569]]. The complex functions in the accurate processing of nuclear RNA precursors and in the degradation of RNAs in both the nucleus and the cytoplasm [[cite:PUB00077701]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0000178
Cellular component Exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
Subterm of
GO:0006396
Biological process RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
Subterm of
Part of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj1g3v4753360.1
– PREDICTED: exosome complex component RRP45-like isoform X3 [Cicer arietinum] gi|502122025|ref|XP_004497542.1|
Domains
14
LotjaGi1g1v0741200.1
– Exosome complex component; TAIR: AT3G60500.1 3'-5'-exoribonuclease family protein; Swiss-Prot: sp|Q9M209|CER7_ARATH Exosome complex component RRP45B; TrEMBL-Plants: tr|G7IP72|G7IP72_MEDTR Exosome complex exonuclease RRP41; Found in the gene: LotjaGi1g1v0741200
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00