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IPR033276 is a E3 ubiquitin-protein ligase BIG BROTHER.
<p>Protein BIG BROTHER is an E3 ubiquitin-protein ligase that limits organ size, and possibly seed size, in a dose-dependent manner. It may limit the duration of organ growth and ultimately organ size by actively degrading critical growth stimulators [[cite:PUB00078318]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Ubiquitin-protein transferase activity | Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. | ||
| Biological process | Protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. | ||
| Biological process | Negative regulation of organ growth | Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: E3 ubiquitin ligase BIG BROTHER-like [Glycine max] gi|356548935|ref|XP_003542854.1| | 3 | ||
| – | PREDICTED: E3 ubiquitin ligase BIG BROTHER-like [Cicer arietinum] gi|502157944|ref|XP_004510966.1| | 12 | ||
| – | PREDICTED: E3 ubiquitin ligase BIG BROTHER-like isoform X3 [Cicer arietinum] gi|502148270|ref|XP_004507101.1| | 12 | ||
| – | RING/U-box superfamily protein, putative; TAIR: AT3G47180.1 RING/U-box superfamily protein; Swiss-Prot: sp|Q9LT17|BBR_ARATH E3 ubiquitin ligase BIG BROTHER-related; TrEMBL-Plants: tr|G7J4X5|G7J4X5_MEDTR Zinc finger, C3HC4 type (RING finger) protein; Found in the gene: LotjaGi1g1v0261000 | 12 | ||
| – | RING/U-box superfamily protein; TAIR: AT3G63530.1 RING/U-box superfamily protein; Swiss-Prot: sp|Q8L649|BB_ARATH E3 ubiquitin ligase BIG BROTHER; TrEMBL-Plants: tr|A0A151R273|A0A151R273_CAJCA E3 ubiquitin-protein ligase rnf12-B; Found in the gene: LotjaGi3g1v0060600 | 11 | ||
| – | RING/U-box superfamily protein; TAIR: AT3G63530.1 RING/U-box superfamily protein; Swiss-Prot: sp|Q8L649|BB_ARATH E3 ubiquitin ligase BIG BROTHER; TrEMBL-Plants: tr|A0A151R273|A0A151R273_CAJCA E3 ubiquitin-protein ligase rnf12-B; Found in the gene: LotjaGi3g1v0060600 | 11 | ||
| – | RING/U-box superfamily protein; TAIR: AT3G63530.1 RING/U-box superfamily protein; Swiss-Prot: sp|Q8L649|BB_ARATH E3 ubiquitin ligase BIG BROTHER; TrEMBL-Plants: tr|A0A151S3R4|A0A151S3R4_CAJCA E3 ubiquitin-protein ligase RLIM; Found in the gene: LotjaGi3g1v0493700 | 9 | ||
| – | RING/U-box superfamily protein; TAIR: AT3G63530.1 RING/U-box superfamily protein; Swiss-Prot: sp|Q8L649|BB_ARATH E3 ubiquitin ligase BIG BROTHER; TrEMBL-Plants: tr|I1LJV4|I1LJV4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0493700 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 12.50 |