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IPR035105 is a Deoxycytidylate deaminase domain.
<p>This entry represents a domain found in a group of deoxycytidylate deaminases.</p> <p>Deoxycytidylate deaminase ([ec:3.5.4.12]) (dCMP deaminase) hydrolyzes deoxycytidylate mono phosphate (dCMP) into deoxyuridine mono phosphate (dUMP), thus providing the nucleotide substrate for thymidylate synthase. The enzyme requires zinc for catalytic activity which is regulated by the ratio of dCTP to dTTP, both the end products of the pyrimidine salvage pathway [[cite:PUB00070796], [cite:PUB00002807], [cite:PUB00047647]]. It contains a cytidine and deoxycytidylate deaminase domain.</p> <p>This domain can also be found in cytidine and dCMP deaminase domain-containing protein 1 (CDADC1), which may play an important role in testicular development and spermatogenesis [[cite:PUB00070799]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Deoxycytidylate deaminase; TAIR: AT3G48540.1 Cytidine/deoxycytidylate deaminase family protein; Swiss-Prot: sp|Q5RC69|DCTD_PONAB Deoxycytidylate deaminase; TrEMBL-Plants: tr|I1K0B7|I1K0B7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0221700 | 20 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 100.00 |