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IPR035994 is a Nucleoside phosphorylase superfamily.
<p>Phosphorylases with this domain include:</p> <ul> <li>Purine nucleoside phosphorylase ([ec:2.4.2.1]) (PNP) from most bacteria (gene deoD), which catalyses the cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules [[cite:PUB00000763]].</li> <li>Uridine phosphorylase ([ec:2.4.2.3]) (UdRPase) from bacteria (gene udp) and mammals, which catalyses the cleavage of uridine into uracil and ribose-1-phosphate, the products of the reaction are used either as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis [[cite:PUB00002902]].</li> <li>5'-methylthioadenosine phosphorylase ([ec:2.4.2.28]) (MTA phosphorylase) from Sulfolobus solfataricus [[cite:PUB00002872]].</li> <li>Purine nucleoside phosphorylase ([ec:2.4.2.1]) (PNP) from mammals as well as from some bacteria (gene deoD). This enzyme catalyzes the cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules [[cite:PUB00002584]].</li> <li>5'-methylthioadenosine phosphorylase ([ec:2.4.2.28]) (MTA phosphorylase) from eukaryotes [[cite:PUB00000256]].</li> </ul>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. | ||
| Biological process | Nucleoside metabolic process | The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine). |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Bark storage protein A; TAIR: AT4G28940.1 Phosphorylase superfamily protein; Swiss-Prot: sp|Q07469|BSPA_POPDE Bark storage protein A; TrEMBL-Plants: tr|I3S0M5|I3S0M5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0402200_LC | 6 | ||
| – | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; TAIR: AT4G28940.1 Phosphorylase superfamily protein; Swiss-Prot: sp|Q07469|BSPA_POPDE Bark storage protein A; TrEMBL-Plants: tr|I1K9C4|I1K9C4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0403400 | 15 | ||
| – | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; TAIR: AT4G28940.1 Phosphorylase superfamily protein; Swiss-Prot: sp|Q07469|BSPA_POPDE Bark storage protein A; TrEMBL-Plants: tr|A0A0B2QEI9|A0A0B2QEI9_GLYSO Bark storage protein A; Found in the gene: LotjaGi1g1v0403400 | 16 | ||
| – | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; TAIR: AT4G28940.1 Phosphorylase superfamily protein; Swiss-Prot: sp|Q07469|BSPA_POPDE Bark storage protein A; TrEMBL-Plants: tr|A0A0B2QEI9|A0A0B2QEI9_GLYSO Bark storage protein A; Found in the gene: LotjaGi1g1v0403800 | 16 | ||
| – | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; TAIR: AT4G28940.1 Phosphorylase superfamily protein; Swiss-Prot: sp|Q07469|BSPA_POPDE Bark storage protein A; TrEMBL-Plants: tr|I1K9C4|I1K9C4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0403800 | 15 | ||
| – | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; TAIR: AT4G28940.1 Phosphorylase superfamily protein; Swiss-Prot: sp|Q07469|BSPA_POPDE Bark storage protein A; TrEMBL-Plants: tr|I1K9C4|I1K9C4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0407000 | 15 | ||
| – | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; TAIR: AT4G38800.1 methylthioadenosine nucleosidase 1; Swiss-Prot: sp|Q9T0I8|MTN1_ARATH 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1; TrEMBL-Plants: tr|I3ST12|I3ST12_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0560700 | 7 | ||
| – | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; TAIR: AT4G38800.1 methylthioadenosine nucleosidase 1; Swiss-Prot: sp|Q9T0I8|MTN1_ARATH 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1; TrEMBL-Plants: tr|I3ST12|I3ST12_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0560700 | 7 | ||
| – | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; TAIR: AT4G28940.1 Phosphorylase superfamily protein; Swiss-Prot: sp|Q07469|BSPA_POPDE Bark storage protein A; TrEMBL-Plants: tr|A0A1J7I7S5|A0A1J7I7S5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0219600 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd09008 | CDD | 1 | 11.11 |