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IPR036574 is a Knottin, scorpion toxin-like superfamily.
<p>Knottins are small proteins characterised by a cystine-knot [[cite:PUB00077056]]. They constitute a large family of structurally related peptides with diverse biological functions, including inhibitors, anti-microbial peptides and toxins [[cite:PUB00077058]]. Their structure is composed of a disulfide-bound fold and contains β-hairpin with two adjacent disulfides.</p> <p>The scorpion toxin-like domain is found in a subgroup of metazoan knottins mainly from the arthropoda, which include the antibacterial defensins [[cite:PUB00000384]] and the scorpion alpha-neurotoxins [[cite:PUB00022373], [cite:PUB00095172]]. The plant sequences include members of the gamma-thionin family, which are plant defensins that have no antifungal activity. Other members are insect alpha-amylase inhibitors, cysteine-rich antifungal proteins and proteins annotated as proteinase inhibitors; those that are characterised belong to MEROPS inhibitor family I18, clan I.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Defensin-like family protein; TAIR: AT5G63660.1 Scorpion toxin-like knottin superfamily protein; Swiss-Prot: sp|Q9FFP8|DEF06_ARATH Defensin-like protein 6; TrEMBL-Plants: tr|A0A061EJM1|A0A061EJM1_THECC Scorpion toxin-like knottin superfamily protein; Found in the gene: LotjaGi1g1v0328600_LC | 17 | ||
| – | Defensin-like protein; TAIR: AT1G19610.1 defensin-like protein; Swiss-Prot: sp|P82787|DEF19_ARATH Defensin-like protein 19; TrEMBL-Plants: tr|A0A072TL50|A0A072TL50_MEDTR Defensin-like protein; Found in the gene: LotjaGi3g1v0086300_LC | 15 | ||
| – | Defensin-like protein; TAIR: AT4G30074.1 low-molecular-weight cysteine-rich 19; Swiss-Prot: sp|P82733|DF183_ARATH Defensin-like protein 183; TrEMBL-Plants: tr|I3SJZ1|I3SJZ1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0237800_LC | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SignalP-noTM | SignalP_GRAM_NEGATIVE | 1 | 33.33 |