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IPR003614

Source: InterPro

Description

IPR003614 is a Knottin, scorpion toxin-like.

<p>Knottins are small proteins characterised by a cystine-knot [[cite:PUB00077056]]. They constitute a large family of structurally related peptides with diverse biological functions, including inhibitors, anti-microbial peptides and toxins [[cite:PUB00077058]].</p> <p>The scorpion toxin-like domain is found in a subgroup of metazoan knottins mainly from the arthropoda, which include the antibacterial defensins [[cite:PUB00000384]] and the scorpion alpha and beta-neurotoxins [[cite:PUB00022373], [cite:PUB00095172]]. The plant sequences include members of the gamma-thionin family, which are plant defensins that have no antifungal activity. Other members are insect alpha-amylase inhibitors, cysteine-rich antifungal proteins and proteins annotated as proteinase inhibitors; those that are characterised belong to MEROPS inhibitor family I18, clan I.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006952
Biological process Defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
Subterm of

Associated Lotus transcripts 8

Transcript Name Description Predicted domains Domain count
Lj0g3v0253209.1
– Defensin precursor [Vigna unguiculata] gi|225548306|gb|ACN93800.1|
Domains
18
Lj0g3v0276939.1
– Scorpion toxin-like knottin superfamily protein [Theobroma cacao] gi|508712956|gb|EOY04853.1|
Domains
17
Lj1g3v1382030.1
– PREDICTED: defensin-like protein 6-like [Glycine max] gi|356516435|ref|XP_003526900.1|
Domains
17
Lj3g3v0720000.1
– PREDICTED: defensin-like protein 19-like [Cicer arietinum] gi|502155954|ref|XP_004510254.1|
Domains
16
Lj4g3v2858510.1
– Scorpion toxin-like knottin superfamily protein [Theobroma cacao] gi|508712956|gb|EOY04853.1|
Domains
17
LotjaGi1g1v0328600_LC.1
– Defensin-like family protein; TAIR: AT5G63660.1 Scorpion toxin-like knottin superfamily protein; Swiss-Prot: sp|Q9FFP8|DEF06_ARATH Defensin-like protein 6; TrEMBL-Plants: tr|A0A061EJM1|A0A061EJM1_THECC Scorpion toxin-like knottin superfamily protein; Found in the gene: LotjaGi1g1v0328600_LC
Domains
17
LotjaGi3g1v0086300_LC.1
– Defensin-like protein; TAIR: AT1G19610.1 defensin-like protein; Swiss-Prot: sp|P82787|DEF19_ARATH Defensin-like protein 19; TrEMBL-Plants: tr|A0A072TL50|A0A072TL50_MEDTR Defensin-like protein; Found in the gene: LotjaGi3g1v0086300_LC
Domains
15
LotjaGi6g1v0237300.1
– Defensin fusion; TAIR: AT5G38330.1 low-molecular-weight cysteine-rich 80; Swiss-Prot: sp|P82789|DF181_ARATH Defensin-like protein 181; TrEMBL-Plants: tr|I3SJZ1|I3SJZ1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0237300
Domains
12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TMhelix TMHMM 1 12.50