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IPR036972

Source: InterPro

Description

IPR036972 is a Cytochrome c oxidase, subunit Vb superfamily.

<p>Cytochrome c oxidase ([ec:7.1.1.9]) is an oligomeric enzymatic complex which is a component of the respiratory chain complex and is involved in the transfer of electrons from cytochrome c to oxygen [[cite:PUB00000581]]. In eukaryotes this enzyme complex is located in the mitochondrial inner membrane; in aerobic prokaryotes it is found in the plasma membrane.</p> <p>In eukaryotes, in addition to the three large subunits, I, II and III, that form the catalytic centre of the enzyme complex, there are a variable number of small polypeptidic subunits. One of these subunits, which is known as Vb in mammals, V in Dictyostelium discoideum (Slime mold) and IV in yeast, binds a zinc atom. The sequence of subunit Vb is well conserved and includes three conserved cysteines that coordinate the zinc ion [[cite:PUB00000625], [cite:PUB00005218]]. Two of these cysteines are clustered in the C-terminal section of the subunit.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004129
Molecular function Cytochrome-c oxidase activity Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
Subterm of
GO:0005740
Cellular component Mitochondrial envelope The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
LotjaGi3g1v0012200.1
– Cytochrome c oxidase subunit 5B, mitochondrial; TAIR: AT1G80230.1 Rubredoxin-like superfamily protein; Swiss-Prot: sp|Q9SSB8|CX5B2_ARATH Cytochrome c oxidase subunit 5b-2, mitochondrial; TrEMBL-Plants: tr|G7IMH7|G7IMH7_MEDTR Cytochrome C oxidase subunit 5b; Found in the gene: LotjaGi3g1v0012200
Domains
10
LotjaGi3g1v0359400.1
– Cytochrome c oxidase subunit 5B, mitochondrial; TAIR: AT1G80230.1 Rubredoxin-like superfamily protein; Swiss-Prot: sp|Q9SSB8|CX5B2_ARATH Cytochrome c oxidase subunit 5b-2, mitochondrial; TrEMBL-Plants: tr|I3SVI7|I3SVI7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0359400
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00924 CDD 1 50.00