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IPR038238

Source: InterPro

Description

IPR038238 is a Clp1, C-terminal domain superfamily.

<p>The yeast Clp1 is a subunit of cleavage factor IA (CF IA) and is involved in mRNA cleavage and polyadenylation [[cite:PUB00075573]]. Clp1 also mediates interactions between CF IA and another complex of the yeast mRNA cleavage and polyadenylation machinery, the Cleavage-Polyadenylation Factor (CPF) [[cite:PUB00074964]]. It seems that human Clp1 and yeast Clp1 are not functional orthologues [[cite:PUB00068902]]. Human Clp1, and its archeal homologue [[cite:PUB00075575]], but not yeast Clp1, are 5'-OH polynucleotide kinases. In humans Clp1 functions as a RNA kinase important in tRNA splicing [[cite:PUB00068902], [cite:PUB00075574]], and is also implicated in mRNA and siRNA maturation [[cite:PUB00044697], [cite:PUB00075577], [cite:PUB00075578]].</p> <p>Clp1 contains three domains, a small N-terminal β sandwich domain, a C-terminal domain containing a novel α/β-fold and a central domain that binds ATP [[cite:PUB00042008]]. This entry represents the Clp1 C-terminal domain superfamily.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi5g1v0360500.4
– Protein CLP1 homolog; TAIR: AT3G04680.1 CLP-similar protein 3; Swiss-Prot: sp|Q9SR06|CLP1_ARATH Protein CLP1 homolog; TrEMBL-Plants: tr|A0A151RWZ1|A0A151RWZ1_CAJCA Protein CLP1 homolog; Found in the gene: LotjaGi5g1v0360500
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 100.00