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IPR040260 is a Replication factor A protein-like.
<p>This entry contains proteins with a winged helix DNA-binding domain, including replication factor A protein 2 (RFA2) and CST complex subunit STN1.</p> <p>Rfa2 (also known as RPA32) is a component of the replication protein A (RPA) complex, which binds to and removes secondary structure from ssDNA. The RPA complex is involved in DNA replication, repair, and recombination [[cite:PUB00070983]].</p> <p>Stn1 is a component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites [[cite:PUB00053884], [cite:PUB00053885], [cite:PUB00153024]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | CST complex subunit STN1; TAIR: AT1G07130.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|Q9LMK5|STN1_ARATH CST complex subunit STN1; TrEMBL-Plants: tr|G7KDM6|G7KDM6_MEDTR OB-fold nucleic acid-binding domain protein; Found in the gene: LotjaGi1g1v0012300_LC | 4 | ||
| – | Replication protein A 32 kDa subunit-like protein; TAIR: AT2G24490.1 replicon protein A2; Swiss-Prot: sp|Q9ZQ19|RFA2A_ARATH Replication protein A 32 kDa subunit A; TrEMBL-Plants: tr|I3SHT3|I3SHT3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0393200 | 18 | ||
| – | CST complex subunit STN1; TAIR: AT1G07130.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|Q9LMK5|STN1_ARATH CST complex subunit STN1; TrEMBL-Plants: tr|G7KDM6|G7KDM6_MEDTR OB-fold nucleic acid-binding domain protein; Found in the gene: LotjaGi3g1v0203800 | 6 | ||
| – | Replication protein A subunit; TAIR: AT3G02920.1 Replication protein A, subunit RPA32; Swiss-Prot: sp|Q8LFJ8|RFA2B_ARATH Replication protein A 32 kDa subunit B; TrEMBL-Plants: tr|A0A151SRU2|A0A151SRU2_CAJCA Replication factor A protein 2; Found in the gene: LotjaGi4g1v0301800 | 15 | ||
| – | Replication protein A 32 kDa subunit-like protein; TAIR: AT2G24490.1 replicon protein A2; Swiss-Prot: sp|Q9ZQ19|RFA2A_ARATH Replication protein A 32 kDa subunit A; TrEMBL-Plants: tr|A0A0L9V123|A0A0L9V123_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0065200 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 20.00 |