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IPR040598 is a 60S ribosome subunit biogenesis protein NIP7, pre-PUA domain.
<p>Human 60S ribosome subunit biogenesis protein NIP7 homologue (also known as KD93) is essential in the accurate processing of pre-rRNA [[cite:PUB00102150]]. The overall fold of KD93 consists of two interlinked α/β domains. The C-terminal domain resembles the PUA domain of some RNA modification enzymes, especially that of archaeosine tRNA-ribosyltransferase (ArcTGT), suggesting a possible molecular function related to RNA binding [[cite:PUB00031177]].</p> <p>This entry represents the N-terminal, pre-PUA domain of NIP7 and its homologues from eukaryotes, and UPF0113 proteins from archaea, whose function is unknown.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | 60S ribosome subunit biogenesis protein NIP7 homolog; TAIR: AT4G15770.1 RNA binding protein; Swiss-Prot: sp|Q6DFH9|NIP7_XENLA 60S ribosome subunit biogenesis protein NIP7 homolog; TrEMBL-Plants: tr|V7CA90|V7CA90_PHAVU 60S ribosome subunit biogenesis protein NIP7 homolog; Found in the gene: LotjaGi6g1v0357900 | 17 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF88802 | SUPERFAMILY | 1 | 100.00 |