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IPR042172

Source: InterPro

Description

IPR042172 is a Adenosylhomocysteinase-like superfamily.

<p>Structural domains found in this superfamily share the structure of the enzyme adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase, AdoHcyase), which is formed in methylation and catalyses the reversible hydration of S-adenosyl-L-homocysteine into adenosine and homocysteine. This enzyme is ubiquitous, highly conserved, and a key regulator of the intracellular concentration of adenosylhomocysteine. In addition, this enzyme is a potent inhibitor of S-adenosyl-L-methionine dependent methyltransferases, and thus plays a critical role in the modulation of their activity [[cite:PUB00021119], [cite:PUB00038377], [cite:PUB00079516], [cite:PUB00079517]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 7

Transcript Name Description Predicted domains Domain count
LotjaGi4g1v0371500.1
– Adenosylhomocysteinase; TAIR: AT4G13940.1 S-adenosyl-L-homocysteine hydrolase; Swiss-Prot: sp|O23255|SAHH1_ARATH Adenosylhomocysteinase 1; TrEMBL-Plants: tr|I1KS65|I1KS65_SOYBN Adenosylhomocysteinase; Found in the gene: LotjaGi4g1v0371500
Domains
21
LotjaGi4g1v0371500.2
– Adenosylhomocysteinase; TAIR: AT4G13940.1 S-adenosyl-L-homocysteine hydrolase; Swiss-Prot: sp|O23255|SAHH1_ARATH Adenosylhomocysteinase 1; TrEMBL-Plants: tr|I1KS65|I1KS65_SOYBN Adenosylhomocysteinase; Found in the gene: LotjaGi4g1v0371500
Domains
19
LotjaGi4g1v0371500.3
– Adenosylhomocysteinase; TAIR: AT4G13940.3 S-adenosyl-L-homocysteine hydrolase; Swiss-Prot: sp|O23255|SAHH1_ARATH Adenosylhomocysteinase 1; TrEMBL-Plants: tr|F4JTV4|F4JTV4_ARATH Adenosylhomocysteinase; Found in the gene: LotjaGi4g1v0371500
Domains
20
LotjaGi4g1v0371500.4
– Adenosylhomocysteinase; TAIR: AT4G13940.1 S-adenosyl-L-homocysteine hydrolase; Swiss-Prot: sp|O23255|SAHH1_ARATH Adenosylhomocysteinase 1; TrEMBL-Plants: tr|I1KS65|I1KS65_SOYBN Adenosylhomocysteinase; Found in the gene: LotjaGi4g1v0371500
Domains
21
LotjaGi6g1v0040900.1
– Adenosylhomocysteinase; TAIR: AT3G23810.1 S-adenosyl-l-homocysteine (SAH) hydrolase 2; Swiss-Prot: sp|P35007|SAHH_CATRO Adenosylhomocysteinase; TrEMBL-Plants: tr|A0A061ELA5|A0A061ELA5_THECC Adenosylhomocysteinase; Found in the gene: LotjaGi6g1v0040900
Domains
21
LotjaGi6g1v0040900.2
– Adenosylhomocysteinase; TAIR: AT3G23810.1 S-adenosyl-l-homocysteine (SAH) hydrolase 2; Swiss-Prot: sp|Q01781|SAHH_PETCR Adenosylhomocysteinase; TrEMBL-Plants: tr|A0A061ELA5|A0A061ELA5_THECC Adenosylhomocysteinase; Found in the gene: LotjaGi6g1v0040900
Domains
19
LotjaGi6g1v0040900.3
– Adenosylhomocysteinase; TAIR: AT4G13940.3 S-adenosyl-L-homocysteine hydrolase; Swiss-Prot: sp|P35007|SAHH_CATRO Adenosylhomocysteinase; TrEMBL-Plants: tr|F4JTV4|F4JTV4_ARATH Adenosylhomocysteinase; Found in the gene: LotjaGi6g1v0040900
Domains
20

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00401 CDD 1 14.29