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PF01053

Description

Cys/Met metabolism PLP-dependent enzyme

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process Transsulfuration The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.
Molecular function Pyridoxal phosphate binding Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

Associated Lotus transcripts 15

Transcript Name Description Predicted domains Domain count
PREDICTED: methionine gamma-lyase-like [Cicer arietinum] gi|502116597|ref|XP_004495508.1| 11
Cystathionine gamma-synthase [Lens culinaris] gi|430736216|gb|AGA60137.1| 8
Pyridoxal phosphate (PLP)-dependent transferases superfamily protein [Arabidopsis thaliana] gi|15217498|ref|NP_174600.1| 8
Cystathionine gamma-synthase [Lens culinaris] gi|430736216|gb|AGA60137.1| 8
Chain A, Cystathionine Gamma-Synthase From Nicotiana Tabacumgi|5822271|pdb|1QGN|B Chain B, Cystathionine Gamma-Synthase From Nicotiana Tabacumgi|5822272|pdb|1QGN|C Chain C, Cystathionine Gamma-Synthase From Nicotiana Tabacumgi|5822273|pdb|1QGN|D Chain D, Cystathionine Gamma-Synthase From Nicotiana Tabacumgi|5822274|pdb|1QGN|E Chain E, Cystathionine Gamma-Synthase From Nicotiana Tabacumgi|5822275|pdb|1QGN|F Chain F, Cystathionine Gamma-Synthase From Nicotiana Tabacumgi|5822276|pdb|1QGN|G Ch 6
PREDICTED: cystathionine beta-lyase, chloroplastic-like [Cicer arietinum] gi|502169960|ref|XP_004514725.1| 10
PREDICTED: cystathionine beta-lyase, chloroplastic-like [Glycine max] gi|356571951|ref|XP_003554134.1| 10
Cystathionine gamma-synthase [Lens culinaris] gi|430736216|gb|AGA60137.1| 6
PREDICTED: cystathionine gamma-synthase, chloroplastic-like [Cicer arietinum] gi|502101187|ref|XP_004491837.1| 20
Cystathionine-gamma-synthase [Medicago truncatula] gi|357496491|ref|XP_003618534.1| 13
Cystathionine gamma-synthase; TAIR: AT3G01120.1 Pyridoxal phosphate (PLP)-dependent transferases superfamily protein; Swiss-Prot: sp|P55217|CGS1_ARATH Cystathionine gamma-synthase 1, chloroplastic; TrEMBL-Plants: tr|L0EKR2|L0EKR2_LENCU Cystathionine gamma-synthase; Found in the gene: LotjaGi1g1v0505500 12
Cystathionine beta-lyase/cystathionine gamma-synthase; TAIR: AT3G57050.3 cystathionine beta-lyase; Swiss-Prot: sp|P53780|METC_ARATH Cystathionine beta-lyase, chloroplastic; TrEMBL-Plants: tr|A0A072VLA8|A0A072VLA8_MEDTR Cystathionine beta-lyase; Found in the gene: LotjaGi2g1v0053000 11
Cystathionine beta-lyase; TAIR: AT3G57050.1 cystathionine beta-lyase; Swiss-Prot: sp|P53780|METC_ARATH Cystathionine beta-lyase, chloroplastic; TrEMBL-Plants: tr|A0A072VLA8|A0A072VLA8_MEDTR Cystathionine beta-lyase; Found in the gene: LotjaGi2g1v0053000 14
Cystathionine gamma-synthase; TAIR: AT3G01120.1 Pyridoxal phosphate (PLP)-dependent transferases superfamily protein; Swiss-Prot: sp|P55217|CGS1_ARATH Cystathionine gamma-synthase 1, chloroplastic; TrEMBL-Plants: tr|G7KKY1|G7KKY1_MEDTR Cystathionine gamma-synthase; Found in the gene: LotjaGi2g1v0260800 13
Cystathionine gamma-lyase; TAIR: AT1G64660.1 methionine gamma-lyase; Swiss-Prot: sp|Q9SGU9|MGL_ARATH Methionine gamma-lyase; TrEMBL-Plants: tr|A0A072VNE2|A0A072VNE2_MEDTR Cystathionine beta-lyase/cystathionine gamma-synthase; Found in the gene: LotjaGi5g1v0200300 12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 6.67