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Anaphase promoting complex subunit 8 / Cdc23
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Anaphase-promoting complex | A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. | ||
| Biological process | Regulation of mitotic metaphase/anaphase transition | Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: anaphase-promoting complex subunit 8-like [Cicer arietinum] gi|502078646|ref|XP_004486012.1| | 16 | ||
| – | Anaphase-promoting complex subunit 8; TAIR: AT3G48150.1 anaphase-promoting complex subunit 8; Swiss-Prot: sp|Q9STS3|CDC23_ARATH Anaphase-promoting complex subunit 8; TrEMBL-Plants: tr|I1LGI1|I1LGI1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0298300 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF48452 | SUPERFAMILY | 1 | 50.00 |