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Nse1 non-SMC component of SMC5-6 complex
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. | ||
| Cellular component | Smc5-Smc6 complex | A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: non-structural maintenance of chromosomes element 1 homolog [Solanum lycopersicum] gi|460365536|ref|XP_004228657.1| | 7 | ||
| – | PREDICTED: non-structural maintenance of chromosomes element 1 homolog [Solanum lycopersicum] gi|460365536|ref|XP_004228657.1| | 7 | ||
| – | Non-structural maintenance of chromosomes element 1 like; TAIR: AT5G21140.1 embryo defective 1379; Swiss-Prot: sp|Q6P881|NSE1_XENTR Non-structural maintenance of chromosomes element 1 homolog; TrEMBL-Plants: tr|I3T4T2|I3T4T2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0191900 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 33.33 |