Domain Predictions — View

Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

PS00533

Source: ProSitePatterns

Description

Porphobilinogen deaminase cofactor-binding site.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

GO term	Namespace	Name	Definition	Relationships
GO:0004418 View details of GO:0004418 AmiGO InterPro QuickGO	Molecular function	Hydroxymethylbilane synthase activity	Catalysis of the reaction: H(2)O + 4 porphobilinogen = hydroxymethylbilane + 4 NH(4)(+).	Subterm of GO:0016765
GO:0018160 View details of GO:0018160 AmiGO InterPro QuickGO	Biological process	Peptidyl-pyrromethane cofactor linkage	The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.	Subterm of GO:0018065 GO:0018198
GO:0033014 View details of GO:0033014 AmiGO InterPro QuickGO	Biological process	Tetrapyrrole biosynthetic process	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.	Subterm of GO:0018130 GO:0019438 GO:0033013 GO:0044271 GO:1901362 GO:1901566

Associated Lotus transcripts 5

Transcript	Name	Description	Predicted domains	Domain count
Lj2g3v2099820.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Porphobilinogen deaminase [Medicago truncatula] gi\|357474093\|ref\|XP_003607331.1\|	Domains G3DSA:3.30.160.40 G3DSA:3.40.190.10 IPR000860 IPR022417 IPR022418 IPR022419 MF_00260 PF01379 PF03900 PIRSF001438 PR00151 PS00533 PTHR11557 SSF53850 SSF54782 TIGR00212 cd13648	17
Lj4g3v2313680.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: porphobilinogen deaminase, chloroplastic-like [Glycine max] gi\|356538495\|ref\|XP_003537739.1\|	Domains G3DSA:3.30.160.40 G3DSA:3.40.190.10 IPR000860 IPR022417 IPR022418 IPR022419 MF_00260 NON_CYTOPLASMIC_DOMAIN PF01379 PF03900 PIRSF001438 PR00151 PS00533 PTHR11557 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF53850 SSF54782 TIGR00212 cd13648	22
LotjaGi2g1v0443900.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Porphobilinogen deaminase; TAIR: AT5G08280.1 hydroxymethylbilane synthase; Swiss-Prot: sp\|Q43082\|HEM3_PEA Porphobilinogen deaminase, chloroplastic; TrEMBL-Plants: tr\|A0A151SCZ0\|A0A151SCZ0_CAJCA Uncharacterized protein; Found in the gene: LotjaGi2g1v0443900	Domains G3DSA:3.30.160.40 G3DSA:3.40.190.10 IPR000860 IPR022417 IPR022418 IPR022419 IPR036803 MF_00260 PF01379 PF03900 PIRSF001438 PR00151 PS00533 PTHR11557 PTHR11557:SF0 SSF53850 SSF54782 TIGR00212 cd13648	19
LotjaGi4g1v0340300.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Porphobilinogen deaminase, putative; TAIR: AT5G08280.1 hydroxymethylbilane synthase; Swiss-Prot: sp\|Q43082\|HEM3_PEA Porphobilinogen deaminase, chloroplastic; TrEMBL-Plants: tr\|A0A151SCZ0\|A0A151SCZ0_CAJCA Uncharacterized protein; Found in the gene: LotjaGi4g1v0340300	Domains G3DSA:3.30.160.40 G3DSA:3.40.190.10 IPR000860 IPR022417 IPR022418 IPR022419 IPR036803 MF_00260 PF01379 PF03900 PIRSF001438 PR00151 PS00533 PTHR11557 PTHR11557:SF0 SSF53850 SSF54782 TIGR00212 cd13648	19
LotjaGi4g1v0340300.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Porphobilinogen deaminase, putative; TAIR: AT5G08280.1 hydroxymethylbilane synthase; Swiss-Prot: sp\|Q43082\|HEM3_PEA Porphobilinogen deaminase, chloroplastic; TrEMBL-Plants: tr\|A0A151SCZ0\|A0A151SCZ0_CAJCA Uncharacterized protein; Found in the gene: LotjaGi4g1v0340300	Domains G3DSA:3.30.160.40 G3DSA:3.40.190.10 IPR000860 IPR022417 IPR022418 IPR022419 IPR036803 PF01379 PF03900 PIRSF001438 PR00151 PS00533 PTHR11557 PTHR11557:SF0 SSF53850 SSF54782 TIGR00212 cd13648	18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
cd13648	CDD	1	20.00