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GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Biological process | DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. | ||
Cellular component | Zeta DNA polymerase complex | A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer. | ||
Biological process | Translesion synthesis | The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | DNA polymerase; TAIR: AT1G67500.1 recovery protein 3; Swiss-Prot: sp|Q766Z3|REV3_ARATH DNA polymerase zeta catalytic subunit; TrEMBL-Plants: tr|I1JRC1|I1JRC1_SOYBN DNA polymerase; Found in the gene: LotjaGi1g1v0772700 | 28 | ||
– | DNA polymerase; TAIR: AT1G67500.1 recovery protein 3; Swiss-Prot: sp|Q766Z3|REV3_ARATH DNA polymerase zeta catalytic subunit; TrEMBL-Plants: tr|I1JRC1|I1JRC1_SOYBN DNA polymerase; Found in the gene: LotjaGi1g1v0772700 | 27 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 50.00 |