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IPR017964 is a DNA-directed DNA polymerase, family B, conserved site.
<p>DNA is the biological information that instructs cells how to exist in an ordered fashion: accurate replication is thus one of the most important events in the life cycle of a cell. This function is performed by DNA- directed DNA-polymerases ([ec:2.7.7.7]) by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA, using a complementary DNA chain as a template. Small RNA molecules are generally used as primers for chain elongation, although terminal proteins may also be used for the<i>de novo</i>synthesis of a DNA chain. Even though there are 2 different methods of priming, these are mediated by 2 very similar polymerases classes, A and B, with similar methods of chain elongation.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Nucleotide binding | Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. | ||
| Molecular function | Nucleic acid binding | Interacting selectively and non-covalently with any nucleic acid. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: DNA polymerase alpha catalytic subunit-like [Vitis vinifera] gi|359480801|ref|XP_002277947.2| | 11 | ||
| – | PREDICTED: DNA polymerase delta catalytic subunit-like [Cicer arietinum] gi|502137074|ref|XP_004502958.1| | 11 | ||
| – | PREDICTED: DNA polymerase alpha catalytic subunit-like [Cicer arietinum] gi|502160825|ref|XP_004511916.1| | 25 | ||
| – | DNA polymerase; TAIR: AT5G63960.1 DNA polymerase delta subunit 1; Swiss-Prot: sp|Q9LRE6|DPOD1_ORYSJ DNA polymerase delta catalytic subunit; TrEMBL-Plants: tr|A0A151ST09|A0A151ST09_CAJCA DNA polymerase; Found in the gene: LotjaGi1g1v0321600 | 29 | ||
| – | DNA polymerase; TAIR: AT5G63960.1 DNA polymerase delta subunit 1; Swiss-Prot: sp|O48901|DPOD1_SOYBN DNA polymerase delta catalytic subunit; TrEMBL-Plants: tr|A0A151ST09|A0A151ST09_CAJCA DNA polymerase; Found in the gene: LotjaGi1g1v0321600 | 26 | ||
| – | DNA polymerase; TAIR: AT5G63960.1 DNA polymerase delta subunit 1; Swiss-Prot: sp|O48901|DPOD1_SOYBN DNA polymerase delta catalytic subunit; TrEMBL-Plants: tr|A0A151ST09|A0A151ST09_CAJCA DNA polymerase; Found in the gene: LotjaGi1g1v0321600 | 26 | ||
| – | DNA polymerase; TAIR: AT1G67500.1 recovery protein 3; Swiss-Prot: sp|Q766Z3|REV3_ARATH DNA polymerase zeta catalytic subunit; TrEMBL-Plants: tr|I1JRC1|I1JRC1_SOYBN DNA polymerase; Found in the gene: LotjaGi1g1v0772700 | 28 | ||
| – | DNA polymerase; TAIR: AT1G67500.1 recovery protein 3; Swiss-Prot: sp|Q766Z3|REV3_ARATH DNA polymerase zeta catalytic subunit; TrEMBL-Plants: tr|I1JRC1|I1JRC1_SOYBN DNA polymerase; Found in the gene: LotjaGi1g1v0772700 | 27 | ||
| – | DNA polymerase; TAIR: AT5G67100.1 DNA-directed DNA polymerase; Swiss-Prot: sp|Q9FHA3|DPOLA_ARATH DNA polymerase alpha catalytic subunit; TrEMBL-Plants: tr|G7K6L8|G7K6L8_MEDTR DNA polymerase; Found in the gene: LotjaGi2g1v0402600 | 34 | ||
| – | DNA polymerase; TAIR: AT5G67100.1 DNA-directed DNA polymerase; Swiss-Prot: sp|Q9FHA3|DPOLA_ARATH DNA polymerase alpha catalytic subunit; TrEMBL-Plants: tr|G7K6L8|G7K6L8_MEDTR DNA polymerase; Found in the gene: LotjaGi3g1v0127800 | 34 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 10.00 |