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GO:0000151

Overview

Field Value
Namespace Cellular component
Short description Ubiquitin ligase complex
Full defintion A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
Subterm of

Relationships

The relationship of GO:0000151 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCjh2
PMID
Proteolysis and the G1-S transition: the SCF connection.
Curr Opin Genet Dev. ; 8 (1): 36–42.PMID: 9529603

Temporal control of ubiquitin-proteasome mediated protein degradation is critical for normal G1 and S phase progression. Recent work has shown that central to the temporal control mechanism is a relationship between newly identified E3 ubiquitin protein ligases, designated SCFs (Skp1-cullin-F-box protein ligase complexes), which confer substrate specificity on ubiquitination reactions and the activities of protein kinases that phosphorylate substrates destined for destruction at specific sites, thereby converting them into preferred targets for ubiquitin modification catalyzed by SCFs. The constituents of SCFs are members of evolutionary conserved protein families. SCF-based ubiquitination pathways may play a key role in diverse biological processes, such as cell proliferation, differentiation and development.

Associated Lotus transcripts 14

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
PREDICTED: E3 ubiquitin-protein ligase RKP-like [Glycine max] gi|356516283|ref|XP_003526825.1| 4
PREDICTED: probable ubiquitin conjugation factor E4-like [Glycine max] gi|356551046|ref|XP_003543890.1| 4
PREDICTED: probable ubiquitin conjugation factor E4-like [Glycine max] gi|356551046|ref|XP_003543890.1| 4
PREDICTED: probable ubiquitin conjugation factor E4-like [Glycine max] gi|356551046|ref|XP_003543890.1| 4
PREDICTED: BRCA1-associated protein-like [Glycine max] gi|356562985|ref|XP_003549748.1| 4
PREDICTED: BRCA1-associated protein-like [Glycine max] gi|356562985|ref|XP_003549748.1| 4
E3 ubiquitin-protein ligase RKP; TAIR: AT2G22010.1 related to KPC1; Swiss-Prot: sp|Q9SIZ8|RKP_ARATH E3 ubiquitin-protein ligase RKP; TrEMBL-Plants: tr|I1KBB2|I1KBB2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0311400 4
E3 ubiquitin-protein ligase RKP; TAIR: AT2G22010.1 related to KPC1; Swiss-Prot: sp|Q9SIZ8|RKP_ARATH E3 ubiquitin-protein ligase RKP; TrEMBL-Plants: tr|I1KBB2|I1KBB2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0311400 4
Ubiquitin conjugation factor E4, putative; TAIR: AT5G15400.1 U-box domain-containing protein; Swiss-Prot: sp|Q9LF41|UBE4_ARATH Probable ubiquitin conjugation factor E4; TrEMBL-Plants: tr|A0A0S3T8K1|A0A0S3T8K1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0263400 4
Ubiquitin conjugation factor E4, putative; TAIR: AT5G15400.1 U-box domain-containing protein; Swiss-Prot: sp|Q9LF41|UBE4_ARATH Probable ubiquitin conjugation factor E4; TrEMBL-Plants: tr|A0A0S3T8K1|A0A0S3T8K1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0263400 4
Ubiquitin conjugation factor E4, putative; TAIR: AT5G15400.1 U-box domain-containing protein; Swiss-Prot: sp|Q9LF41|UBE4_ARATH Probable ubiquitin conjugation factor E4; TrEMBL-Plants: tr|A0A0S3T8K1|A0A0S3T8K1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0263400 4
Ubiquitin conjugation factor E4, putative; TAIR: AT5G15400.1 U-box domain-containing protein; Swiss-Prot: sp|Q9LF41|UBE4_ARATH Probable ubiquitin conjugation factor E4; TrEMBL-Plants: tr|A0A0S3T8K1|A0A0S3T8K1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0263400 4
Ubiquitin conjugation factor E4, putative; TAIR: AT5G15400.1 U-box domain-containing protein; Swiss-Prot: sp|Q9LF41|UBE4_ARATH Probable ubiquitin conjugation factor E4; TrEMBL-Plants: tr|A0A0R0EU58|A0A0R0EU58_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0263500_LC 4
BRCA1-associated protein; TAIR: AT2G42160.1 zinc finger (ubiquitin-hydrolase) domain-containing protein; Swiss-Prot: sp|Q7Z569|BRAP_HUMAN BRCA1-associated protein; TrEMBL-Plants: tr|I1MU69|I1MU69_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0273800 4

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
Biological process Protein ubiquitination 1 7.14