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GO:0005786

View this GO term in other databases

Overview

Field Value
Namespace Cellular component
Short description Signal recognition particle, endoplasmic reticulum targeting
Full defintion A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. Examples of this component are found in Mus musculus, Saccharomyces cerevisiae and Arabidopsis thaliana.
Subterm of

Relationships

The relationship of GO:0005786 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCmtg_sensu
ISBN

· ISBN: 0198506732

, · pages

Associated Lotus transcripts 8

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0111119.1
– PREDICTED: signal recognition particle 68 kDa protein-like isoform X1 [Cicer arietinum] gi|502139530|ref|XP_004503804.1|
GO terms
5
Lj0g3v0111119.3
– PREDICTED: signal recognition particle 68 kDa protein-like isoform X1 [Cicer arietinum] gi|502139530|ref|XP_004503804.1|
GO terms
5
Lj4g3v2871930.1
– PREDICTED: signal recognition particle 68 kDa protein-like isoform X1 [Cicer arietinum] gi|502139530|ref|XP_004503804.1|
GO terms
5
Lj4g3v2871930.2
– PREDICTED: signal recognition particle 68 kDa protein-like isoform X1 [Cicer arietinum] gi|502139530|ref|XP_004503804.1|
GO terms
5
LotjaGi2g1v0434000.1
– Signal recognition particle 14 kDa protein; TAIR: AT2G43640.1 Signal recognition particle, SRP9/SRP14 subunit; Swiss-Prot: sp|O04421|SRP14_ARATH Signal recognition particle 14 kDa protein; TrEMBL-Plants: tr|I3SA11|I3SA11_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0434000
GO terms
4
LotjaGi4g1v0421900.1
– Signal recognition particle subunit SRP68; TAIR: AT5G61970.1 signal recognition particle-related / SRP-like protein; Swiss-Prot: sp|Q8BMA6|SRP68_MOUSE Signal recognition particle subunit SRP68; TrEMBL-Plants: tr|G7LIT8|G7LIT8_MEDTR Signal recognition particle subunit SRP68; Found in the gene: LotjaGi4g1v0421900
GO terms
5
LotjaGi4g1v0421900.2
– Signal recognition particle subunit SRP68; TAIR: AT5G61970.1 signal recognition particle-related / SRP-like protein; Swiss-Prot: sp|Q8BMA6|SRP68_MOUSE Signal recognition particle subunit SRP68; TrEMBL-Plants: tr|G7LIT8|G7LIT8_MEDTR Signal recognition particle subunit SRP68; Found in the gene: LotjaGi4g1v0421900
GO terms
5
LotjaGi4g1v0421900.3
– Signal recognition particle subunit SRP68; TAIR: AT5G61970.1 signal recognition particle-related / SRP-like protein; Swiss-Prot: sp|Q8BMA6|SRP68_MOUSE Signal recognition particle subunit SRP68; TrEMBL-Plants: tr|G7LIT8|G7LIT8_MEDTR Signal recognition particle subunit SRP68; Found in the gene: LotjaGi4g1v0421900
GO terms
5

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0030942
Molecular function Endoplasmic reticulum signal peptide binding 1 12.50