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GO:0005832

Overview

Field Value
Namespace Cellular component
Short description Chaperonin-containing T-complex
Full defintion A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
Subterm of

Relationships

The relationship of GO:0005832 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0005832, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCsgd_curators
PMID
Review: cellular substrates of the eukaryotic chaperonin TRiC/CCT.
J Struct Biol. ; 135 (2): 176–84.PMID: 11580267

The TCP-1 ring complex (TRiC; also called CCT, for chaperonin containing TCP-1) is a large (approximately 900 kDa) multisubunit complex that mediates protein folding in the eukaryotic cytosol. The physiological substrate spectrum of TRiC is still poorly defined. Genetic and biochemical data show that it is required for the folding of the cytoskeletal proteins actin and tubulin. Recent years have witnessed a steady stream of reports that describe other proteins that require TRiC for proper folding. Furthermore, analysis of the transit of newly synthesized proteins through TRiC in intact cells suggests that the chaperonin contributes to the folding of a distinct subset of cellular proteins. Here we review the current understanding of a role for TRiC in the folding of newly synthesized polypeptides, with a focus on some of the individual proteins that require TRiC.

Associated Lotus transcripts 9

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
PREDICTED: T-complex protein 1 subunit beta-like isoform X2 [Cicer arietinum] gi|502104047|ref|XP_004492422.1| 4
T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A1J7HDU4|A0A1J7HDU4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0438900 4
T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A1J7HDU4|A0A1J7HDU4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0438900 4
T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|I1LRE4|I1LRE4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0438900 4
T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|I1LRE4|I1LRE4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0438900 4
T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A1J7HDU4|A0A1J7HDU4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0438900 4
T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A151TNM7|A0A151TNM7_CAJCA T-complex protein 1 subunit beta; Found in the gene: LotjaGi6g1v0145000 4
T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A151TNM7|A0A151TNM7_CAJCA T-complex protein 1 subunit beta; Found in the gene: LotjaGi6g1v0145000 4
T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A151TNM7|A0A151TNM7_CAJCA T-complex protein 1 subunit beta; Found in the gene: LotjaGi6g1v0145000 4

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
Molecular function Unfolded protein binding 1 11.11