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GO:0008278

View this GO term in other databases

Overview

Field Value
Namespace Cellular component
Short description Cohesin complex
Full defintion A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
Subterm of

Relationships

The relationship of GO:0008278 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCvw
PMID
SMC-mediated chromosome mechanics: a conserved scheme from bacteria to vertebrates?Hirano T
Genes Dev. 1999 Jan 1; 13 (1): 11–9.PMID: 9887095

Associated Lotus transcripts 8

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
LotjaGi1g1v0488400.1
– Sister chromatid cohesion 1 protein; TAIR: AT5G16270.1 sister chromatid cohesion 1 protein 4; Swiss-Prot: sp|Q8W1Y0|SSC14_ARATH Sister chromatid cohesion 1 protein 4; TrEMBL-Plants: tr|A0A0B2S710|A0A0B2S710_GLYSO Sister chromatid cohesion 1 protein 3; Found in the gene: LotjaGi1g1v0488400
GO terms
2
LotjaGi1g1v0620400.2
– Sister chromatid cohesion 1 protein; TAIR: AT5G40840.1 Rad21/Rec8-like family protein; Swiss-Prot: sp|Q9FQ20|SCC12_ARATH Sister chromatid cohesion 1 protein 2; TrEMBL-Plants: tr|G7L499|G7L499_MEDTR Sister chromatid cohesion 1 protein; Found in the gene: LotjaGi1g1v0620400
GO terms
2
LotjaGi3g1v0125000.1
– Sister chromatid cohesion 1 protein; TAIR: AT3G59550.1 Rad21/Rec8-like family protein; Swiss-Prot: sp|Q9FQ19|SCC13_ARATH Sister chromatid cohesion 1 protein 3; TrEMBL-Plants: tr|A0A1J7GHV5|A0A1J7GHV5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0125000
GO terms
2
LotjaGi5g1v0181700.1
– Structural maintenance of chromosomes protein; TAIR: AT3G54670.1 Structural maintenance of chromosomes (SMC) family protein; Swiss-Prot: sp|Q6Q1P4|SMC1_ARATH Structural maintenance of chromosomes protein 1; TrEMBL-Plants: tr|A0A0S3SRB6|A0A0S3SRB6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0181700
GO terms
4
LotjaGi5g1v0181700.2
– Structural maintenance of chromosomes protein; TAIR: AT3G54670.1 Structural maintenance of chromosomes (SMC) family protein; Swiss-Prot: sp|Q6Q1P4|SMC1_ARATH Structural maintenance of chromosomes protein 1; TrEMBL-Plants: tr|A0A0S3SRB6|A0A0S3SRB6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0181700
GO terms
4
LotjaGi5g1v0181700.3
– Structural maintenance of chromosomes protein; TAIR: AT3G54670.1 Structural maintenance of chromosomes (SMC) family protein; Swiss-Prot: sp|Q6Q1P4|SMC1_ARATH Structural maintenance of chromosomes protein 1; TrEMBL-Plants: tr|A0A0B2P8J7|A0A0B2P8J7_GLYSO Structural maintenance of chromosomes protein; Found in the gene: LotjaGi5g1v0181700
GO terms
4
LotjaGi5g1v0181700.4
– Structural maintenance of chromosomes protein; TAIR: AT3G54670.1 Structural maintenance of chromosomes (SMC) family protein; Swiss-Prot: sp|Q6Q1P4|SMC1_ARATH Structural maintenance of chromosomes protein 1; TrEMBL-Plants: tr|I1LYK3|I1LYK3_SOYBN Structural maintenance of chromosomes protein; Found in the gene: LotjaGi5g1v0181700
GO terms
4
LotjaGi5g1v0181700.5
– Structural maintenance of chromosomes protein; TAIR: AT3G54670.1 Structural maintenance of chromosomes (SMC) family protein; Swiss-Prot: sp|Q6Q1P4|SMC1_ARATH Structural maintenance of chromosomes protein 1; TrEMBL-Plants: tr|A0A0S3SR98|A0A0S3SR98_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0181700
GO terms
4

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0046982
Molecular function Protein heterodimerization activity 1 12.50