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| Field | Value |
|---|---|
| Namespace | Biological process |
| Short description | Mitotic sister chromatid cohesion |
| Full defintion | The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission. |
| Subterm of |
The relationship of GO:0007064 with other GO terms.
| Relationship type | GO terms |
|---|---|
| Is a | |
| Regulates | n.a. |
| Part of | |
| Positively regulates | n.a. |
| Negatively regulates | n.a. |
A force layout showing the ancestor tree for GO:0007064, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
This table contains additional metadata associated with the GO entry's definition field.
| Field | Value |
|---|---|
| GOC | rn |
| PMID | Pds5p regulates the maintenance of sister chromatid cohesion and is sumoylated to promote the dissolution of cohesion. J Cell Biol. 2003 Nov 24; 163 (4): 729–41.PMID: 14623866 Pds5p and the cohesin complex are required for sister chromatid cohesion and localize to the same chromosomal loci over the same cell cycle window. However, Pds5p and the cohesin complex likely have distinct roles in cohesion. We report that pds5 mutants establish cohesion, but during mitosis exhibit precocious sister dissociation. Thus, unlike the cohesin complex, which is required for cohesion establishment and maintenance, Pds5p is required only for maintenance. We identified SMT4, which encodes a SUMO isopeptidase, as a high copy suppressor of both the temperature sensitivity and precocious sister dissociation of pds5 mutants. In contrast, SMT4 does not suppress temperature sensitivity of cohesin complex mutants. Pds5p is SUMO conjugated, with sumoylation peaking during mitosis. SMT4 overexpression reduces Pds5p sumoylation, whereas smt4 mutants have increased Pds5p sumoylation. smt4 mutants were previously shown to be defective in cohesion maintenance during mitosis. These data provide the first link between a protein required for cohesion, Pds5p, and sumoylation, and suggest that Pds5p sumoylation promotes the dissolution of cohesion. |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| Transcript | Name | Description | GO terms | GO count |
|---|---|---|---|---|
| – | PREDICTED: sister chromatid cohesion protein DCC1-like [Cicer arietinum] gi|502100504|ref|XP_004491735.1| | 2 | ||
| – | PREDICTED: sister chromatid cohesion protein DCC1-like [Cicer arietinum] gi|502100504|ref|XP_004491735.1| | 2 | ||
| – | PREDICTED: chromosome transmission fidelity protein 8 homolog [Glycine max] gi|356559833|ref|XP_003548201.1| | 2 | ||
| – | Sister chromatid cohesion protein PDS5 like B-B; TAIR: AT4G31880.1 transcriptional regulator; Swiss-Prot: sp|Q04264|PDS5_YEAST Sister chromatid cohesion protein PDS5; TrEMBL-Plants: tr|I3S8P0|I3S8P0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0099300 | 1 | ||
| – | Sister chromatid cohesion protein PDS5 like B-B; TAIR: AT4G31880.1 transcriptional regulator; Swiss-Prot: sp|Q04264|PDS5_YEAST Sister chromatid cohesion protein PDS5; TrEMBL-Plants: tr|I3S8P0|I3S8P0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0099300 | 1 | ||
| – | MAU2 chromatid cohesion factor like; TAIR: AT5G51340.1 Tetratricopeptide repeat (TPR)-like superfamily protein; Swiss-Prot: sp|Q16NZ8|SCC4_AEDAE MAU2 chromatid cohesion factor homolog; TrEMBL-Plants: tr|V7BAU7|V7BAU7_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0103300 | 1 | ||
| – | MAU2 chromatid cohesion factor like; TAIR: AT5G51340.1 Tetratricopeptide repeat (TPR)-like superfamily protein; Swiss-Prot: sp|Q16NZ8|SCC4_AEDAE MAU2 chromatid cohesion factor homolog; TrEMBL-Plants: tr|V7BAU7|V7BAU7_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0103300 | 1 | ||
| – | MAU2 chromatid cohesion factor like; TAIR: AT5G51340.1 Tetratricopeptide repeat (TPR)-like superfamily protein; Swiss-Prot: sp|Q16NZ8|SCC4_AEDAE MAU2 chromatid cohesion factor homolog; TrEMBL-Plants: tr|V7BAU7|V7BAU7_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0103300 | 1 | ||
| – | MAU2 chromatid cohesion factor like; TAIR: AT5G51340.1 Tetratricopeptide repeat (TPR)-like superfamily protein; Swiss-Prot: sp|Q16NZ8|SCC4_AEDAE MAU2 chromatid cohesion factor homolog; TrEMBL-Plants: tr|V7BAU7|V7BAU7_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0103300 | 1 | ||
| – | MAU2 chromatid cohesion factor like; TAIR: AT5G51340.1 Tetratricopeptide repeat (TPR)-like superfamily protein; Swiss-Prot: sp|O15743|SPNA_DICDI Protein spalten; TrEMBL-Plants: tr|K7KAE5|K7KAE5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0103300 | 1 | ||
| – | Sister chromatid cohesion PDS5-like protein; TAIR: AT1G77600.2 ARM repeat superfamily protein; Swiss-Prot: sp|A4L9P7|PDS5A_RAT Sister chromatid cohesion protein PDS5 homolog A; TrEMBL-Plants: tr|K7LX49|K7LX49_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0160100 | 1 | ||
| – | Sister chromatid cohesion protein PDS5 like B-B; TAIR: AT4G31880.2 transcriptional regulator; Swiss-Prot: sp|Q5U241|PD5BB_XENLA Sister chromatid cohesion protein PDS5 homolog B-B; TrEMBL-Plants: tr|A0A0B2R5L9|A0A0B2R5L9_GLYSO Sister chromatid cohesion protein PDS5 like B-B; Found in the gene: LotjaGi1g1v0378300_LC | 1 | ||
| – | Sister chromatid cohesion protein PDS5 like B-B; TAIR: AT4G31880.2 transcriptional regulator; Swiss-Prot: sp|Q5U241|PD5BB_XENLA Sister chromatid cohesion protein PDS5 homolog B-B; TrEMBL-Plants: tr|A0A0B2R5L9|A0A0B2R5L9_GLYSO Sister chromatid cohesion protein PDS5 like B-B; Found in the gene: LotjaGi1g1v0378300_LC | 1 | ||
| – | Sister chromatid cohesion protein PDS5 like B-B; TAIR: AT4G31880.2 transcriptional regulator; Swiss-Prot: sp|Q5U241|PD5BB_XENLA Sister chromatid cohesion protein PDS5 homolog B-B; TrEMBL-Plants: tr|A0A0B2R5L9|A0A0B2R5L9_GLYSO Sister chromatid cohesion protein PDS5 like B-B; Found in the gene: LotjaGi1g1v0378300_LC | 1 | ||
| – | Sister chromatid cohesion protein PDS5 like B-B; TAIR: AT4G31880.2 transcriptional regulator; Swiss-Prot: sp|Q5U241|PD5BB_XENLA Sister chromatid cohesion protein PDS5 homolog B-B; TrEMBL-Plants: tr|A0A0B2R5L9|A0A0B2R5L9_GLYSO Sister chromatid cohesion protein PDS5 like B-B; Found in the gene: LotjaGi1g1v0378300_LC | 1 | ||
| – | Sister chromatid cohesion protein PDS5 like B; TAIR: AT5G47690.1 binding protein; Swiss-Prot: sp|O43312|MTSS1_HUMAN Metastasis suppressor protein 1; TrEMBL-Plants: tr|A2Q1R4|A2Q1R4_MEDTR HEAT; Found in the gene: LotjaGi1g1v0438100_LC | 1 | ||
| – | Sister chromatid cohesion protein DCC1; TAIR: AT2G44580.1 zinc ion binding protein; Swiss-Prot: sp|Q66I84|DCC1_DANRE Sister chromatid cohesion protein DCC1; TrEMBL-Plants: tr|I1KFJ4|I1KFJ4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0604100 | 2 | ||
| – | Chromosome transmission fidelity protein 8; TAIR: AT5G52220.1 chromosome transmission fidelity-like protein; Swiss-Prot: sp|P0CG15|CTF8_MOUSE Chromosome transmission fidelity protein 8 homolog; TrEMBL-Plants: tr|I1MPY4|I1MPY4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0145300 | 2 | ||
| – | Chromosome transmission fidelity protein 8; TAIR: AT5G52220.1 chromosome transmission fidelity-like protein; Swiss-Prot: sp|P0CG15|CTF8_MOUSE Chromosome transmission fidelity protein 8 homolog; TrEMBL-Plants: tr|A0A0S3TAX3|A0A0S3TAX3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0145300 | 2 | ||
| – | Sister chromatid cohesion protein PDS5 like B-B; TAIR: AT1G15940.1 Tudor/PWWP/MBT superfamily protein; Swiss-Prot: sp|Q6A026|PDS5A_MOUSE Sister chromatid cohesion protein PDS5 homolog A; TrEMBL-Plants: tr|K7L820|K7L820_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0350400 | 1 | ||
| – | Sister chromatid cohesion protein PDS5 like B-B; TAIR: AT1G15940.1 Tudor/PWWP/MBT superfamily protein; Swiss-Prot: sp|Q6A026|PDS5A_MOUSE Sister chromatid cohesion protein PDS5 homolog A; TrEMBL-Plants: tr|K7L820|K7L820_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0350600 | 1 | ||
| – | Sister chromatid cohesion protein PDS5 like B; TAIR: AT5G47690.3 binding protein; Swiss-Prot: sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B; TrEMBL-Plants: tr|K7MJA4|K7MJA4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0005800 | 1 | ||
| – | Sister chromatid cohesion protein PDS5 like B-B; TAIR: AT4G31880.2 transcriptional regulator; Swiss-Prot: sp|Q5U241|PD5BB_XENLA Sister chromatid cohesion protein PDS5 homolog B-B; TrEMBL-Plants: tr|A0A151RT93|A0A151RT93_CAJCA Sister chromatid cohesion protein PDS5 isogeny B-B; Found in the gene: LotjaGi5g1v0054300 | 1 | ||
| – | Sister chromatid cohesion protein PDS5 like B-B; TAIR: AT4G31880.1 transcriptional regulator; Swiss-Prot: sp|Q5U241|PD5BB_XENLA Sister chromatid cohesion protein PDS5 homolog B-B; TrEMBL-Plants: tr|A0A151RT93|A0A151RT93_CAJCA Sister chromatid cohesion protein PDS5 isogeny B-B; Found in the gene: LotjaGi5g1v0054300 | 1 | ||
| – | Structural maintenance of chromosomes protein; TAIR: AT3G54670.1 Structural maintenance of chromosomes (SMC) family protein; Swiss-Prot: sp|Q6Q1P4|SMC1_ARATH Structural maintenance of chromosomes protein 1; TrEMBL-Plants: tr|A0A0S3SRB6|A0A0S3SRB6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0181700 | 4 | ||
| – | Structural maintenance of chromosomes protein; TAIR: AT3G54670.1 Structural maintenance of chromosomes (SMC) family protein; Swiss-Prot: sp|Q6Q1P4|SMC1_ARATH Structural maintenance of chromosomes protein 1; TrEMBL-Plants: tr|A0A0S3SRB6|A0A0S3SRB6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0181700 | 4 | ||
| – | Structural maintenance of chromosomes protein; TAIR: AT3G54670.1 Structural maintenance of chromosomes (SMC) family protein; Swiss-Prot: sp|Q6Q1P4|SMC1_ARATH Structural maintenance of chromosomes protein 1; TrEMBL-Plants: tr|A0A0B2P8J7|A0A0B2P8J7_GLYSO Structural maintenance of chromosomes protein; Found in the gene: LotjaGi5g1v0181700 | 4 | ||
| – | Structural maintenance of chromosomes protein; TAIR: AT3G54670.1 Structural maintenance of chromosomes (SMC) family protein; Swiss-Prot: sp|Q6Q1P4|SMC1_ARATH Structural maintenance of chromosomes protein 1; TrEMBL-Plants: tr|I1LYK3|I1LYK3_SOYBN Structural maintenance of chromosomes protein; Found in the gene: LotjaGi5g1v0181700 | 4 | ||
| – | Structural maintenance of chromosomes protein; TAIR: AT3G54670.1 Structural maintenance of chromosomes (SMC) family protein; Swiss-Prot: sp|Q6Q1P4|SMC1_ARATH Structural maintenance of chromosomes protein 1; TrEMBL-Plants: tr|A0A0S3SR98|A0A0S3SR98_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0181700 | 4 | ||
| – | Sister chromatid cohesion protein PDS5 like B; TAIR: AT5G47690.1 binding protein; Swiss-Prot: sp|Q5U241|PD5BB_XENLA Sister chromatid cohesion protein PDS5 homolog B-B; TrEMBL-Plants: tr|K7MAX3|K7MAX3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0282400 | 1 |
A list of co-occurring GO terms within the L. japonicus gene space:
| GO term | Namespace | Name | Observations | Saturation (%) |
|---|---|---|---|---|
| Biological process | Mitotic sister chromatid cohesion | 1 | 3.33 |