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GO:0008534

View this GO term in other databases

Overview

Field Value
Namespace Molecular function
Short description Oxidized purine nucleobase lesion DNA N-glycosylase activity
Full defintion Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.
Subterm of

Relationships

The relationship of GO:0008534 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCelh
PMID
DNA glycosylases: specificity and mechanisms.Mitra S
Prog Nucleic Acid Res Mol Biol. 2001; 68 (): 189–92.PMID: 11554296

Associated Lotus transcripts 8

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0134359.1
– PREDICTED: N-glycosylase/DNA lyase OGG1-like isoform X1 [Cicer arietinum] gi|502135915|ref|XP_004502497.1|
GO terms
3
Lj0g3v0181229.1
– N-glycosylase/DNA lyase [Medicago truncatula] gi|357463557|ref|XP_003602060.1|
GO terms
3
Lj3g3v0044230.1
– PREDICTED: formamidopyrimidine-DNA glycosylase-like isoform X2 [Cicer arietinum] gi|502080701|ref|XP_004486650.1|
GO terms
4
Lj3g3v0044230.2
– PREDICTED: formamidopyrimidine-DNA glycosylase-like isoform X1 [Cicer arietinum] gi|502080698|ref|XP_004486649.1|
GO terms
4
LotjaGi1g1v0263300.1
– N-glycosylase/DNA lyase; TAIR: AT1G21710.1 8-oxoguanine-DNA glycosylase 1; Swiss-Prot: sp|Q9FNY7|OGG1_ARATH N-glycosylase/DNA lyase OGG1; TrEMBL-Plants: tr|A0A0S3RDM0|A0A0S3RDM0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0263300
GO terms
3
LotjaGi3g1v0007500.1
– Formamidopyrimidine-DNA glycosylase; TAIR: AT1G52500.2 MUTM homolog-1; Swiss-Prot: sp|O80358|FPG_ARATH Formamidopyrimidine-DNA glycosylase; TrEMBL-Plants: tr|A0A151SPP2|A0A151SPP2_CAJCA Formamidopyrimidine-DNA glycosylase; Found in the gene: LotjaGi3g1v0007500
GO terms
4
LotjaGi3g1v0007500.2
– Formamidopyrimidine-DNA glycosylase; TAIR: AT1G52500.2 MUTM homolog-1; Swiss-Prot: sp|O80358|FPG_ARATH Formamidopyrimidine-DNA glycosylase; TrEMBL-Plants: tr|G7II90|G7II90_MEDTR Formamidopyrimidine-DNA glycosylase; Found in the gene: LotjaGi3g1v0007500
GO terms
4
LotjaGi3g1v0007500.3
– Formamidopyrimidine-DNA glycosylase; TAIR: AT1G52500.1 MUTM homolog-1; Swiss-Prot: sp|O80358|FPG_ARATH Formamidopyrimidine-DNA glycosylase; TrEMBL-Plants: tr|A0A151SPP2|A0A151SPP2_CAJCA Formamidopyrimidine-DNA glycosylase; Found in the gene: LotjaGi3g1v0007500
GO terms
4

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0008534
Molecular function Oxidized purine nucleobase lesion DNA N-glycosylase activity 1 12.50