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| Field | Value |
|---|---|
| Gene ID | Lj0g3v0134359 |
| Transcript ID | Lj0g3v0134359.1 |
| Lotus japonicus genome version | MG20 v3.0 |
| Description | PREDICTED: N-glycosylase/DNA lyase OGG1-like isoform X1 [Cicer arietinum] gi|502135915|ref|XP_004502497.1| |
| Working Lj name | n.a. |
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | 1 | 241 | 241 | 1.70E-131 | – | |
| PANTHER | 1 | 241 | 241 | 1.70E-131 | – | |
| Pfam | 1 | 33 | 33 | 1.30E-04 | ||
| Gene3D | 28 | 143 | 116 | 1.20E-41 | ||
| SUPERFAMILY | 28 | 209 | 182 | 4.87E-39 | ||
| CDD | 30 | 208 | 179 | 7.58E-27 | ||
| Pfam | 34 | 169 | 136 | 1.50E-11 | ||
| SMART | 38 | 211 | 174 | 2.10E-14 | ||
| Gene3D | 144 | 211 | 68 | 9.00E-30 |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Damaged DNA binding | Interacting selectively and non-covalently with damaged DNA. | ||
| Molecular function | Catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. | ||
| Biological process | DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. | ||
| Biological process | Base-excision repair | In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. | ||
| Biological process | Nucleotide-excision repair | A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). | ||
| Molecular function | Oxidized purine nucleobase lesion DNA N-glycosylase activity | Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site. |
Expression pattern of Lj0g3v0134359.1, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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A list of the top 25 highly co-expressed genes of Lj0g3v0134359.1, powered by CORGI.
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