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Field | Value |
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Namespace | Cellular component |
Short description | NURF complex |
Full defintion | An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters. |
Subterm of |
The relationship of GO:0016589 with other GO terms.
Relationship type | GO terms |
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Is a | |
Regulates | n.a. |
Part of | n.a. |
Positively regulates | n.a. |
Negatively regulates | n.a. |
A force layout showing the ancestor tree for GO:0016589, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
This table contains additional metadata associated with the GO entry's definition field.
Field | Value |
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GOC | krc |
PMID | Chromatin remodelling in mammalian cells by ISWI-type complexes--where, when and why? FEBS J. 2011 Oct; 278 (19): 3608–18.PMID: 21810179 The specific location of nucleosomes on DNA has important inhibitory or activating roles in the regulation of DNA-dependent processes as it affects the DNA accessibility. Nucleosome positions depend on the ATP-coupled activity of chromatin-remodelling complexes that translocate nucleosomes or evict them from the DNA. The mammalian cell harbors numerous different remodelling complexes that possess distinct activities. These can translate a variety of signals into certain patterns of nucleosome positions with specific functions. Although chromatin remodellers have been extensively studied in vitro, much less is known about how they operate in their cellular environment. Here, we review the cellular activities of the mammalian imitation switch proteins and discuss mechanisms by which they are targeted to sites where their activity is needed. |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
Transcript | Name | Description | GO terms | GO count |
---|---|---|---|---|
– | SNF2 super family [Bathycoccus prasinos] gi|412991118|emb|CCO15963.1| | 3 | ||
– | SNF2 super family [Bathycoccus prasinos] gi|412991118|emb|CCO15963.1| | 3 | ||
– | SNF2 super family [Bathycoccus prasinos] gi|412991118|emb|CCO15963.1| | 3 | ||
– | Chromatin remodeling complex subunit [Medicago truncatula] gi|357447407|ref|XP_003593979.1| | 3 | ||
– | Chromatin remodeling complex subunit [Medicago truncatula] gi|357447407|ref|XP_003593979.1| | 3 |
A list of co-occurring GO terms within the L. japonicus gene space:
GO term | Namespace | Name | Observations | Saturation (%) |
---|---|---|---|---|
Biological process | ATP-dependent chromatin remodeling | 1 | 20.00 |