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GO:1990879

View this GO term in other databases

Overview

Field Value
Namespace Cellular component
Short description CST complex
Full defintion A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection.
Subterm of

Relationships

The relationship of GO:1990879 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:1990879, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCnc
PMID
The telomere syndromes.Armanios M, Blackburn EH
Nat Rev Genet. 2012 Oct; 13 (10): 693–704.PMID: 22965356

There has been mounting evidence of a causal role for telomere dysfunction in a number of degenerative disorders. Their manifestations encompass common disease states such as idiopathic pulmonary fibrosis and bone marrow failure. Although these disorders seem to be clinically diverse, collectively they comprise a single syndrome spectrum defined by the short telomere defect. Here we review the manifestations and unique genetics of telomere syndromes. We also discuss their underlying molecular mechanisms and significance for understanding common age-related disease processes.

Associated Lotus transcripts 4

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj1g3v1785760.1
– PREDICTED: CST complex subunit TEN1-like [Cicer arietinum] gi|502113192|ref|XP_004494570.1|
GO terms
2
LotjaGi1g1v0365900.1
– CST complex subunit TEN1; TAIR: AT1G56260.1 telomere-capping, CST complex subunit; Swiss-Prot: sp|Q6NME7|TEN1_ARATH CST complex subunit TEN1; TrEMBL-Plants: tr|C6SVF8|C6SVF8_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi1g1v0365900
GO terms
2
LotjaGi1g1v0365900.2
– CST complex subunit TEN1; TAIR: AT1G56260.1 telomere-capping, CST complex subunit; Swiss-Prot: sp|Q6NME7|TEN1_ARATH CST complex subunit TEN1; TrEMBL-Plants: tr|C6SVF8|C6SVF8_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi1g1v0365900
GO terms
2
LotjaGi1g1v0365900.3
– CST complex subunit TEN1; TAIR: AT1G56260.1 telomere-capping, CST complex subunit; Swiss-Prot: sp|Q6NME7|TEN1_ARATH CST complex subunit TEN1; TrEMBL-Plants: tr|C6SVF8|C6SVF8_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi1g1v0365900
GO terms
2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:1990879
Cellular component CST complex 1 25.00