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| Field | Value |
|---|---|
| Gene ID | LotjaGi1g1v0058300 |
| Transcript ID | LotjaGi1g1v0058300.1 |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | 3-hydroxy-3-methylglutaryl coenzyme A reductase; TAIR: AT1G76490.1 hydroxy methylglutaryl CoA reductase 1; Swiss-Prot: sp|P29057|HMDH1_HEVBR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1; TrEMBL-Plants: tr|I1JIP4|I1JIP4_SOYBN 3-hydroxy-3-methylglutaryl coenzyme A reductase; Found in the gene: LotjaGi1g1v0058300 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr1:8139503..8143978) extracted from Lotus japonicus Gifu genome v1.2.
AAGCGGCAGATGTAATTTATCTTTTCGAATTATAAAAAATGTAAATAGTTGTCCTCTTTAAACATCTAATCCAAGTCTGA TTAACGTGATTTCAGACCCTCAGAAAAATTAGTGATTATAGGATGTAACTTATGAATCAAAAATAAAAAAATAAATTACA ATTAAAATAAAATAAAAAGCAAAAAAAAACAAAAAACAGCAAATAGCAATGGAGGTGGGTCCGGTAACAGCGTAGCACCT TCGCTGGCAGACACACTCACAACCCTTCATTTATTCCAAACATTCTTCTCTCTTCCCTTCTCTTTAACCCTTCCTTCTTC CCTCATTCTCACCACCACCACCGTCATGGACCTCCACCGCCGGCCACCTCCCTCCGGCGACCACATCGCCGCCGTGGTCA GGCACCACCGTCGTAAACGACCTTCCTCCACTTCCCCCATTCCAAAGGCCTCCGACGCGCTACCTCTCCCGTTGTATCTC ACCAACGCGATCTTCTTCACGCTCTTCTTCTCCGTCGCGTACTACCTCCTCCACCGCTGGCGCGACAAGATCCGCAGCTC CACACCTCTCCACGTCGTTACTCTCTCCGAGATCACCGCCATTGTCTCCCTCATCGCGTCCTTCATCTACCTCCTCGGTT TCTTCGGCATCGATTTCGTCCAATCGTTCATCTCACGCGCTTCCAATGACATCTGGGAGGAAGACGACGACGTCTCCGCC GCTGACAACAAACCAACCCCCAAGGTTCAACCACCACCGCCGGTGGAAACCCCGGAGGAGGATGAGGAGATTGTGAGGTC GGTGGTGGAGGGTGATACACCTTCATACGCGCTGGAATCGAGGCTTGGAGATTGTCGTCGCGCCGCCGCGATTCGCCGGG AGGCGCTGCAGAGGTTGACGGGGAGGTCGTTGGAGGGTTTGCCGTTGGAAGGGTTTGATTACGAGTCGATTTTGGGGCAA TGCTGTGAAATGCCGGTGGGGTATGTTCAGATTCCGGTGGGGGTGGCGGGGCCGTTGTTGTTGGATGGGTTTGAGCACAC GGTGCCGATGGCGACGACGGAAGGGTGCTTGGTGGCGAGTACTAACAGAGGGTGTAAGGCGATTTACGCTTCCGGTGGGG CGAGTAGTGTGGTGTTGAAAGATGCTATGTCAAGAGCACCGGTTGTTAGATTTGCTACTGCTAAGAGAGCTGCACAGTTG AAATTCTTCTTGGAGGATCCTCTCAATTTTGATACATTGGCTGTTGTTTTCAACAGGTTAGCTTCAATTTTTGTGTATGA TTTTGTGGTTGGAGAAATTGTTGTTGTTATGTAGCTTTTTTGTCTTATGGGGTAGGTCTTAGGATGGAATCAAATCACAC ACTGAAGCTTTCATTTTATTGATTTCCATTTGTGTGAAATTCATTGAATCACATGTTTTGATTTGATTTGATTCTCAATA ACTTAGTGGATCCTTTTTCCAATTTGATGGGACTAGCCAAATTTTCAATATGAGCTTTGCTTGGAGTGTATACTAGTAAG GGTTATAACTAAGTAATGTTTTTGATAATATGATAAAATAAAGTGGGAAGCTTTTTTGAAAAACAATATATTTGTGGCAT TGGAAATAACGAGTGCAGTATGGTCTTTCTTTAGTAAGAAAGACTTCCCACTTTTGTATTCTTATTCTATGCAATGTTGC ATAGGTTATAATAACCGGATTTAGCTCATCTAAAGTGAGAGAGTCACACTAGAGTATAACGTAAGTCATCACATGTTCAC AATCATTAATAGTGATTATGTACTTTTAACGGTCAATAAAGCAACTCAATCAATGGTTGTGATGACCTACTTTACCCTCT AAAGTGAGAGAAAAGTGAGTGAGTCTCTCACTTTAGAGGAGCCAGACCCAAGGAACTAAACGTTCTTTGTTGGTTGAAAA CCCCTGTATATGTGGGAAATACTCTTTGGTATGAAAAATCTTCCCTAAAAGTTGCATGAATGAATATCATTAATTGAGAT AAAATAAGTAATGGCCCACCATATATTGTTACTGTGGTCTTGTGGATTCTCTTTTATCATAGACACGTCTCTATTATTTT TTTTGTGTTTTCAATATTTTGGTTGTTTATTTGTATCTTTAATTTTTTTCCCATTTTTCTGAGTTTGATATTGATATTTT TTTAATGTTGGATGTTTAAAAACTGTGGAAAGATGGTGAAGAAAATAAGGATGTTATTTTTTAAAATTTATACTGACTTA TGATGTTTCATTTCTGTTGGTTTCAGGTCAAGTAGATTTGCCAGGCTTCAAGGTATTCAGTGTGCTATGGCTGGGAAGAA CATTTATTTGAGATTCACCTGCAGCACGGGTGATGCCATGGGGATGAACATGGTCTCCAAAGGAGTTCAGAATGTTCTTG ACTTCCTTCAAAATGATTTCCCTGACATGGATATTATTGGCATCTCTGGTAATTTCCAATTCCTTTTCCACTTTAATGGA TGGGATTTCCTGGATCGTTCTTTAGTAAGCCTGCATGATGTCATGAATACAACTAATGTGGTATATGCAATCACACGCTG TCTCTTTTTGTCTCCTATCAGTTATATAGTGGTTTCTTTCATGAAAGTGGTCCAATTGCATTATCTTATTTCTTTCAGTG TCATCTTTTGACGTTTTGGTCTTTTTTATATTATATTATATTATTTTAGGTCCTATCTGATTTGAACAGGATACTTGTGC CATATAATGGTGTTGCTGAAGAGTTTCTGTTTGAATTCTAATCTGAGCTTGATTTGTTTATCTGCCTGCTTTAAAAAAAA GGGTTGATCTACTAATATGTATGTAACTCAATGTTATTTGCTAGAGTGATCATATTTTTTGAATCTGCTCCTATTGTGTG TACTACTAGTATTAATTCTTTCCTCATGTGGAATCAAGTTTAGTAGTTATTCTTGAAGTTAACTTGTATCTTTTGAACTT CTCATTATTATTTGATACCTATTATCAAGGCAAACTGAATTAATTTAAATGGGAACATAAGACCAAAAATGTGATGTTTT TGTCCTGACTTGATCCTTTAGGAAACTATTGTTCGGACAAGAAACCTGCTGCTATAAACTGGATTGAGGGACGGGGTAAA TCAGTTGTTTGTGAAGCAATTATCAAAGAAGATGTGGTGAAGAAGGTATTGAAGACTAATGTTGCTGCCCTTGTGGAGCT TAACATGCTCAAAAACCTTGCTGGTTCTGCTGTTGCCGGTGCTCTCGGTGGATTCAACGCACATGCTAGTAACATAGTTT CTGCAGTATTTTTAGCCACCGGTCAAGATCCTGCTCAAAATGTTGAAAGCTCCCATTGCATAACAATGATGGAAGCCGTT AATGATGGAAGAGACCTTCATATCTCAGTGACTATGCCTTCCATTGAGGTAATCTTTCATCCATGTATTCATAGATTTTA CTCCCAAGCTTATGGGTTTGGGAGAGTTTATGACATACCTATAAGCTGTTTTGAGCTTATTTTCATAAGCTGCTCATATA AGCCTTAATAGCTCTACCTCTAAGCCTTTATTTTACATGATTCATTGTCCTTTCAGGTTGGTACTGTTGGTGGTGGGACT CAACTTGCATCTCAGTCCGCTTGCTTGAATTTGCTTGGTGTGAAGGGTGCCAGCAAGGAGTCACCAGGATCAAATTCGAG ACTCTTGGCCACCGTTGTCGCCGGAGCTGTTTTAGCCGGAGAACTGTCTCTGATGTCTGCCATTGCTGCAGGGCAGCTAG TGAACAGCCACATGAAATACAACAGATCAAGCAAAGATGTATGCAAAGTACTAACATCTTAAGGACAAAGATGTGGTGGT TGTCATTATTTGTTGTGAATTCTAAAATAAAAACACCAAGCTCTGAGCCCGAAATCCGGAATTTAGGGAAGAAAATGCAA AATGGAAGGCATTAGATTAGATTGTTGGCACTCAAGTTTGGCTCTGTATTGATATGTATTATTTGGTTGGAGGAAAATAG AGTTCTACCTGTTTGGTGTACATGTTTGGTAGCTTATTCTGCAGAGCCATTTGGATATGGGTGTTGGCATTCTGCTTCTC CTTAACCGAGACATTTGACGTGTTGTATTAAAATTCTTTTCCTGATATAATATGTACCTACCATTGTTTATGATCCATTT GTTTCTGTGTAGTTGGGGACCATGTAACCGAGTGGTTTGATGTTTTTTTCTCTTGTCATGTTGTCCGTTAGTACCCATGA ATTCAATTTGACCATGTCTTTCCTATGTTTTCCCATTCTGTCAGTGTTGGATATTACAGAGATTGCTGATTAAACTTTGT AAGATACTTGACGTATTTCATTGGCACATTGCTACTTCTGTTCAAGCATAATAATCATCAAAATCAATGTGTTCGCTTGT CTCTGTAGTTAACCATTGCTAGAGACAACAACAACAAATAGAGTAAAATTACTAGGTGCTGGTTTGAAAATTCTTC
CDS sequence (LotjaGi1g1v0058300.1) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGGACCTCCACCGCCGGCCACCTCCCTCCGGCGACCACATCGCCGCCGTGGTCAGGCACCACCGTCGTAAACGACCTTC CTCCACTTCCCCCATTCCAAAGGCCTCCGACGCGCTACCTCTCCCGTTGTATCTCACCAACGCGATCTTCTTCACGCTCT TCTTCTCCGTCGCGTACTACCTCCTCCACCGCTGGCGCGACAAGATCCGCAGCTCCACACCTCTCCACGTCGTTACTCTC TCCGAGATCACCGCCATTGTCTCCCTCATCGCGTCCTTCATCTACCTCCTCGGTTTCTTCGGCATCGATTTCGTCCAATC GTTCATCTCACGCGCTTCCAATGACATCTGGGAGGAAGACGACGACGTCTCCGCCGCTGACAACAAACCAACCCCCAAGG TTCAACCACCACCGCCGGTGGAAACCCCGGAGGAGGATGAGGAGATTGTGAGGTCGGTGGTGGAGGGTGATACACCTTCA TACGCGCTGGAATCGAGGCTTGGAGATTGTCGTCGCGCCGCCGCGATTCGCCGGGAGGCGCTGCAGAGGTTGACGGGGAG GTCGTTGGAGGGTTTGCCGTTGGAAGGGTTTGATTACGAGTCGATTTTGGGGCAATGCTGTGAAATGCCGGTGGGGTATG TTCAGATTCCGGTGGGGGTGGCGGGGCCGTTGTTGTTGGATGGGTTTGAGCACACGGTGCCGATGGCGACGACGGAAGGG TGCTTGGTGGCGAGTACTAACAGAGGGTGTAAGGCGATTTACGCTTCCGGTGGGGCGAGTAGTGTGGTGTTGAAAGATGC TATGTCAAGAGCACCGGTTGTTAGATTTGCTACTGCTAAGAGAGCTGCACAGTTGAAATTCTTCTTGGAGGATCCTCTCA ATTTTGATACATTGGCTGTTGTTTTCAACAGGTCAAGTAGATTTGCCAGGCTTCAAGGTATTCAGTGTGCTATGGCTGGG AAGAACATTTATTTGAGATTCACCTGCAGCACGGGTGATGCCATGGGGATGAACATGGTCTCCAAAGGAGTTCAGAATGT TCTTGACTTCCTTCAAAATGATTTCCCTGACATGGATATTATTGGCATCTCTGGAAACTATTGTTCGGACAAGAAACCTG CTGCTATAAACTGGATTGAGGGACGGGGTAAATCAGTTGTTTGTGAAGCAATTATCAAAGAAGATGTGGTGAAGAAGGTA TTGAAGACTAATGTTGCTGCCCTTGTGGAGCTTAACATGCTCAAAAACCTTGCTGGTTCTGCTGTTGCCGGTGCTCTCGG TGGATTCAACGCACATGCTAGTAACATAGTTTCTGCAGTATTTTTAGCCACCGGTCAAGATCCTGCTCAAAATGTTGAAA GCTCCCATTGCATAACAATGATGGAAGCCGTTAATGATGGAAGAGACCTTCATATCTCAGTGACTATGCCTTCCATTGAG GTTGGTACTGTTGGTGGTGGGACTCAACTTGCATCTCAGTCCGCTTGCTTGAATTTGCTTGGTGTGAAGGGTGCCAGCAA GGAGTCACCAGGATCAAATTCGAGACTCTTGGCCACCGTTGTCGCCGGAGCTGTTTTAGCCGGAGAACTGTCTCTGATGT CTGCCATTGCTGCAGGGCAGCTAGTGAACAGCCACATGAAATACAACAGATCAAGCAAAGATGTATGCAAAGTACTAACA TCTTAA
Protein sequence (LotjaGi1g1v0058300.1) extracted from Lotus japonicus Gifu v1.2 Proteins.
MDLHRRPPPSGDHIAAVVRHHRRKRPSSTSPIPKASDALPLPLYLTNAIFFTLFFSVAYYLLHRWRDKIRSSTPLHVVTL SEITAIVSLIASFIYLLGFFGIDFVQSFISRASNDIWEEDDDVSAADNKPTPKVQPPPPVETPEEDEEIVRSVVEGDTPS YALESRLGDCRRAAAIRREALQRLTGRSLEGLPLEGFDYESILGQCCEMPVGYVQIPVGVAGPLLLDGFEHTVPMATTEG CLVASTNRGCKAIYASGGASSVVLKDAMSRAPVVRFATAKRAAQLKFFLEDPLNFDTLAVVFNRSSRFARLQGIQCAMAG KNIYLRFTCSTGDAMGMNMVSKGVQNVLDFLQNDFPDMDIIGISGNYCSDKKPAAINWIEGRGKSVVCEAIIKEDVVKKV LKTNVAALVELNMLKNLAGSAVAGALGGFNAHASNIVSAVFLATGQDPAQNVESSHCITMMEAVNDGRDLHISVTMPSIE VGTVGGGTQLASQSACLNLLGVKGASKESPGSNSRLLATVVAGAVLAGELSLMSAIAAGQLVNSHMKYNRSSKDVCKVLT S
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| Phobius | 1 | 40 | 40 | - | – | |
| PANTHER | 1 | 558 | 558 | 0.0 | – | |
| PANTHER | 1 | 558 | 558 | 0.0 | ||
| TMHMM | 40 | 62 | 23 | - | – | |
| Phobius | 41 | 62 | 22 | - | – | |
| Phobius | 63 | 82 | 20 | - | – | |
| TMHMM | 75 | 97 | 23 | - | – | |
| Phobius | 83 | 102 | 20 | - | – | |
| Phobius | 103 | 515 | 413 | - | – | |
| MobiDBLite | 121 | 146 | 26 | - | – | |
| Gene3D | 142 | 216 | 75 | 1.7E-20 | ||
| SUPERFAMILY | 143 | 539 | 397 | 1.06E-104 | ||
| TIGRFAM | 146 | 550 | 405 | 1.5E-159 | ||
| ProSiteProfiles | 146 | 550 | 405 | 141.359 | ||
| CDD | 149 | 550 | 402 | 0.0 | ||
| Pfam | 174 | 550 | 377 | 1.1E-141 | ||
| PRINTS | 206 | 227 | 22 | 7.4E-87 | ||
| Gene3D | 217 | 537 | 321 | 5.8E-141 | ||
| PRINTS | 233 | 253 | 21 | 7.4E-87 | ||
| Gene3D | 267 | 383 | 117 | 5.8E-141 | ||
| SUPERFAMILY | 268 | 383 | 116 | 9.42E-46 | ||
| PRINTS | 324 | 342 | 19 | 7.4E-87 | ||
| ProSitePatterns | 326 | 340 | 15 | - | ||
| PRINTS | 364 | 389 | 26 | 7.4E-87 | ||
| PRINTS | 415 | 441 | 27 | 7.4E-87 | ||
| PRINTS | 469 | 490 | 22 | 7.4E-87 | ||
| ProSitePatterns | 481 | 488 | 8 | - | ||
| Phobius | 516 | 542 | 27 | - | – | |
| ProSitePatterns | 535 | 548 | 14 | - | ||
| Phobius | 543 | 561 | 19 | - | – |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Hydroxymethylglutaryl-CoA reductase (NADPH) activity | Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH. | ||
| Molecular function | Protein binding | Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). | ||
| Biological process | Isoprenoid biosynthetic process | The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. | ||
| Biological process | Coenzyme A metabolic process | The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. | ||
| Molecular function | Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP. | ||
| Molecular function | Coenzyme binding | Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
Expression pattern of LotjaGi1g1v0058300.1, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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