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Hydroxymethylglutaryl-coenzyme A reductase
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Hydroxymethylglutaryl-CoA reductase (NADPH) activity | Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH. | ||
| Biological process | Coenzyme A metabolic process | The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. | ||
| Molecular function | Coenzyme binding | Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3-like [Cicer arietinum] gi|502153809|ref|XP_004509470.1| | 22 | ||
| – | PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3-like [Cicer arietinum] gi|502153809|ref|XP_004509470.1| | 22 | ||
| – | PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1-like [Cicer arietinum] gi|502161813|ref|XP_004512291.1| | 27 | ||
| – | Hydroxy-methyl-glutaryl-coenzyme A reductase [Bacopa monnieri] gi|256681158|gb|ACV04940.1| | 20 | ||
| – | PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1-like [Glycine max] gi|356501322|ref|XP_003519474.1| | 27 | ||
| – | 3-hydroxy-3-methylglutaryl coenzyme A reductase; TAIR: AT1G76490.1 hydroxy methylglutaryl CoA reductase 1; Swiss-Prot: sp|P29057|HMDH1_HEVBR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1; TrEMBL-Plants: tr|I1JIP4|I1JIP4_SOYBN 3-hydroxy-3-methylglutaryl coenzyme A reductase; Found in the gene: LotjaGi1g1v0058300 | 27 | ||
| – | 3-hydroxy-3-methylglutaryl coenzyme A reductase; TAIR: AT1G76490.1 hydroxy methylglutaryl CoA reductase 1; Swiss-Prot: sp|P29057|HMDH1_HEVBR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1; TrEMBL-Plants: tr|A9YVC3|A9YVC3_MEDTR 3-hydroxy-3-methylglutaryl coenzyme A reductase; Found in the gene: LotjaGi2g1v0352700 | 27 | ||
| – | 3-hydroxy-3-methylglutaryl coenzyme A reductase; TAIR: AT1G76490.1 hydroxy methylglutaryl CoA reductase 1; Swiss-Prot: sp|P29057|HMDH1_HEVBR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1; TrEMBL-Plants: tr|A0A075EC73|A0A075EC73_ASTME 3-hydroxy-3-methylglutaryl coenzyme A reductase; Found in the gene: LotjaGi2g1v0352700 | 27 | ||
| – | 3-hydroxy-3-methylglutaryl coenzyme A reductase; TAIR: AT1G76490.1 hydroxy methylglutaryl CoA reductase 1; Swiss-Prot: sp|O64967|HMDH2_GOSHI 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2; TrEMBL-Plants: tr|E0X6S2|E0X6S2_GLYUR 3-hydroxy-3-methylglutaryl coenzyme A reductase; Found in the gene: LotjaGi4g1v0140100_LC | 22 | ||
| – | 3-hydroxy-3-methylglutaryl coenzyme A reductase; TAIR: AT1G76490.1 hydroxy methylglutaryl CoA reductase 1; Swiss-Prot: sp|O64967|HMDH2_GOSHI 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2; TrEMBL-Plants: tr|E0X6S2|E0X6S2_GLYUR 3-hydroxy-3-methylglutaryl coenzyme A reductase; Found in the gene: LotjaGi4g1v0140100_LC | 22 | ||
| – | 3-hydroxy-3-methylglutaryl coenzyme A reductase; TAIR: AT1G76490.1 hydroxy methylglutaryl CoA reductase 1; Swiss-Prot: sp|O64967|HMDH2_GOSHI 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2; TrEMBL-Plants: tr|E0X6S2|E0X6S2_GLYUR 3-hydroxy-3-methylglutaryl coenzyme A reductase; Found in the gene: LotjaGi4g1v0140100_LC | 22 | ||
| – | 3-hydroxy-3-methylglutaryl coenzyme A reductase; TAIR: AT1G76490.1 hydroxy methylglutaryl CoA reductase 1; Swiss-Prot: sp|O64967|HMDH2_GOSHI 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2; TrEMBL-Plants: tr|E0X6S2|E0X6S2_GLYUR 3-hydroxy-3-methylglutaryl coenzyme A reductase; Found in the gene: LotjaGi4g1v0140100_LC | 22 | ||
| – | 3-hydroxy-3-methylglutaryl coenzyme A reductase; TAIR: AT1G76490.1 hydroxy methylglutaryl CoA reductase 1; Swiss-Prot: sp|O64967|HMDH2_GOSHI 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2; TrEMBL-Plants: tr|E0X6S2|E0X6S2_GLYUR 3-hydroxy-3-methylglutaryl coenzyme A reductase; Found in the gene: LotjaGi4g1v0140100_LC | 22 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00643 | CDD | 1 | 7.69 |