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LotjaGi2g1v0191500.3

Overview

Field Value
Gene ID LotjaGi2g1v0191500
Transcript ID LotjaGi2g1v0191500.3
Related isoforms 5
Lotus japonicus genome version Gifu v1.2
Description Guanine nucleotide-binding protein subunit alpha-like protein; TAIR: AT1G31930.1 extra-large GTP-binding protein 3; Swiss-Prot: sp|Q9C516|XLG3_ARATH Extra-large guanine nucleotide-binding protein 3; TrEMBL-Plants: tr|K7L0X8|K7L0X8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0191500
Working Lj name n.a.

Sequence information

Genomic sequence (LjG1.1_chr2:62291066..62299185) extracted from Lotus japonicus Gifu genome v1.2.

AGCTGACAACTTGAGACTCAGAAGAAGACCTCCTTCTCTTCTTTCTGATCCAAACCTTTCTACTCTCTTCCCTTTCTCTC CAACTAAACTTTCTCTCTCACTTTCCTTCCAACTTTCCCGCACTTTCTCACCATCCAAACACCCCCAATGGCCTCCGAAC CCGCCGACGAAGACAACAACACCTGGGAGCACGTCCTCCGCCGCATGCTCCCCGTCGGAGCTCCGATGCCAGACGAGGAG CAACTCGACTACTCCATCGCCGTCGAGTACGAAGGACCTCCTGTCCAATACCACATCCCTAGGGTTGATCCGCTCGAAGT AGCTTCCACCGCCGCCGCCTCCTCCGCCCCGATTCGCAACTCCGATCACGCCGCGGCCGCAATTCCCATCGCCATGCCGC TTCACCCTCGATTCTCAAGGTTTGGAATCGTCCGTAACGGCGGTTACGGCCGCGAGCCGCGGAGTCCGGTTGAGAGTCAG AGACCGTCTTCGGTGTCGCCGAATCAGTCTCAGTTTGAGTCTGGCAACGGCGGCGGCGACGTCGATCCCGACGATTTTTC CGGTGAGCCTGTTGCGGACACTGCCAGCGGTGGTTCGTCTCCGGCTCGGTCGTGGACTGTTCCGAACAGCGGCGCCGTCG AGGGTAAGCGCCCGACGACGGTGACGTTCAACACTCCGAGGGATTCGTCATCTGACGACGGCAGTTACCTCTCGCCGCAG TCTGTAGCGACGGAGCCGGTGGGATCGCCGGCGGCTTCTGCGTCTGCGCGGAACGCGCAGACGAAGCGGTGGGTTTGCAG CAGATGTGGGAATAAGAACAGGTTGAAGGAGAAGGAAGCGTGTTTGGTGTGTGATGCGAGGTACTGCTGCAACTGTGTGC TGAAGGCCATGGGGTCGATGCCGGAGGGGAGGAAATGCGTGAGCTGCATTGGGCAGGCCATTGATGAGTCGAAGAGATCG AGCTTGGGGAAGTGTTCGAGGATGCTGAGTAGGGTTTGTAGTCCATTGGAGATTAATCAGATCATGAAGGCTGAGAAGGA GTGTGCTGCTAATCAGCTGCGGCCGGAGCAGCTAATCGTCAATGGGCGCCAGTTGAGGCAGGAAGAGTTGGCTGAGATTC TGGGCTGCGCGATACCGCCTCAGAAGTTGAAGCCAGGGAGGTATTGGTATGATAAGGATTCTGGATACTGGGGCAAGGTG AACATGAAAAACAGAAAACAGAAAGAAAGAAAATTTAGTGTTTTGATATGCTGAAAATGTGCCACTAAAGTGTAATTGTC TGTAATGTGAGGAAACAAACATATTTTCACTTTTGGATCTTTGCGGGTTAAGATCTTTCTCACTTTATAGACAAGTGCAC TTTAGAGGTGCCTTATCTTCAATATGAAGTGTTTATGTTTTATGTTTGTTCTTGGTTTTGTATAGAAACTACTATTTTTA GATTGTTTTGTTGTTTTGCTTAGTTTGGAAGTTGTGGATTTCAGGAGGGAGAGAAGCCTGATAGGATAATAAGTTCAAAG CTAAATATTGGAGGGAAGCTTCAAACAGATGCAAGCAATGGAAATACTAGAGTCTACATGAATGGCCGTGAAATAACAAA GATTGAGCTTAGAATGTTAAAGGTAATCATGTTTTTCCTTGCATTTTAGTTTGGATAAAGTTCAGAGCAAAATCGTAGAA CATAGAAATTCCTATATGTGCTAGAAGGCTAGATGCCAACTTGAATTTTGTGTGTTTTCTTGCTTGCCGGAACCCTCTTG AGTCTTGACTGAATATTAACTGCAGAATTTTGTGTTTATAAGGCAATTGATTGTCCTTCAAAGAATATTGCTCACCAATC TTCCGATGGAGCAAAAAAAAAAAGAATATTGCTCACCAAAGCAATGAAATATTTTGTGAAGTTTATCTTGAATGAAAGAC AGGAAGAACCTTTCCATGGGACAATCCTGCTTCCCTCTTTTGATTTCATTTAGACCATCTTAAGTGAAAGAAACCTTGAA TCTTGTTTTCTCATTCCTGTCTATATAATATTGATCTAATTATAGACCATTAAGAGTTTCCTTTTGATCTTTAGATCTGA CTTCATTGGACTTTGGAAATATAAAATTGCACTTTGTATATCTGTTTGTAATTTATTGCTCTTATCAACACCAATCAATT TGTAACTTGTTTGGCTGTCATTTTAGCTTGCAAATGTTCAATGCCCGCGAGACACCCATTTCTGGGTTTATGATGATGGC TCTTATGAGGAAGAAGGCCAAAATAATATTAAAGGGAACATATGGGGAAAGGTTCTCTCTTACCTAATATAATATATATA TATGTATATATATATATATGTATATATATATATGTATATATATATATGTATATATATATATATATCTACTGTTTAATTTG AGCTTGAAAGCGGATGCCTTGATTTGGTTTTTTTATACAATATCGATTTGGTTTATGGTAGGCAGGCGTCCACTCGTTTG ATTTGTTCATTATGCTCATTGCCTGTACCACCTACTAATCCTCCTGGGGTCAAAGATAATCTGACTAACTATTCAACAAG GTCTGTGCCTGAGTATTTAGAGCAAGGTAGAGTTCAGAAACTATTGTTGTTTGGTATGGAAGGATCTGGAACAGCCACTC TGTTTAAACAGGCATGTCTAACTATTCCTTTCTCTTTCACATCTCTCGCACTCTCTCCCCCTCTCTGTGTCATAGTTTCT TGTATCCATGCCTTTCCGTGTTATAAATTCTAATGTGCCTGATTCGGGTCAATACCTTTGGCTTTCCTTCGGGCAAAAGG CTTTAGTGAAGGTTCATATTTTATATGCTCAGTTTGAAGCTCAACAGGTGCTGGTGGACTGCTAGTTATAATAGTCCATC CATAGTAATACAATTGACTGTTTTCTATGGATTTAGATGTGTTATTATCAACTATTTTACTCAATGCAAAAAATAAATGT TTTAAACATAGTTTGATTATGCATGCACACATCCGTACTCTCAGAAGTACATGCTATATAATATAACTAGGTTTTTGCTT ATGTATGGGTAATGCATATGCACACCTGCACATGCCAAAATTTCGATGCATAAAGGTTATATGTGCTTGCCATATTCGTA AAATAGGCCAATGCATACTCGTAGATGTTTACATATATTCATATACACTTAGATGTATATGTAACTAAATAGAAGTTTTA TTTTGTATAGTTTCAACATTTCGGATGTGTATTCACTTTCAGCTTACGTGTAATGTAAACTCTGCCTTGCCCCTTTTTCG AGTGCTTTCTAATAATGCCTATTATGGATGGCTTTTCATTGTACACTTGGCGGTCTTTTCTTTATTTTATTTTTTTAAAT CTGCAAGTTTTAGTTTAAATGGCTGACTCACTTTTTAACATCTTGCAAGGGTTTTCCTTTACCTAATTACTTTGAGTTTA TGCTACAGTGTCAACTATTTTTATTGTTCTCATTTTACTGTTTCCGTGCTTTCTTTATGAGAATAATGTTTTTCCTTGTC CTTGAATCAGGCCAAGTTTTTATATGGAAACAAGTTTTCTCCAGAAGAGTTGCAAAACATTAAACTCATGATTCAAAGCA ATATGTACAAGTATCTCAGCATTCTGCTTGAAGGACGAGAGCAGTTTGAAGAGGAAGCTCTGGCAGAGAAAGAATGTGCC TCGTTAGAAGATGAAGAATCTGGACCTGGTATAACATTTTATTTTATTTTTCCTTCAGGCACAAAATATACATTTTTCTT CAAAAAGTTCCACAGTGCTTGTAAGTTATGAAGTTGAGTGATAAGTTATGCGGTTGTAGTTAGTTGGAGAGCCCAAGGCC TTATAAACCCCTCATTAGAATCCCATACTTCCAATGAGGGACTCAAGTCCCATACCTTGCAATTAGATCCTAACATTGAG CTGTATATTTCTTTCTCTCACCGTCTCCATTTTTTGTCAACATTTCTATGTTTATCTCAAATTATTGTCCAATCAGAACA TTTAATGAAGAGTACCCATATTAGTTATGTGGGATGAGGGAGGGAGAGAGGGAACAATAAGTGCTTAAGTGCTTTATGTG GCCCTTATGTGGCACATAAAGGTCACTTTTGGATAACAGACTTCTCTGATTCTTTCTTGATGTACTGCATCTTTGCAATT TTGCTCCAACATGCAATAAACTCATTACGTTATGCAGATGTTAAACTTATAAAACTTAACTTCAGGTAACTTATTTATAT TTTGTCTGACAATATTGAACATGTATTATAATAAAGACGACGATATAAACTTGTAATAGGAACAGCCATCAAGGTTTATC TCACTAATTGAATTGAGTTCTATCAAAAACCAAATATTCAATAAAACCATATAATGTAAAGTACTTCTTAATGGTTACTT GTTGTCATGTTAAGGTTTCTTTCTACTAGTGGTCCATTGTTACGCGACAAAACAAATATGCTATAACTGCTATGTTGGAT GATTTATCCTTTTAAGGAACAATTTTTCCAATAACAATTCTTGATAGCTAATAGTTGTGTTGGATTCTGTGGATGATGAA AGTTGGTAATAATCTTTTTGTTAATATCTTTGAAAAGTTGGGTTTATGTGAGTGAATCTGATTGTGCAATAAATTCAGCA GAAAGAGCAGCTGAGGAAAACAAACCAACCATTTACTCGATCAATCAAAGACTCAAGCATTTTTCTGACTGGTTGCTGGA TATTATGGCTACGGGGGATTTGGAGGCTTTCTTCCCTGCTGCTACGCGTGAGTATGCTCCTATGGTAGAGGAGATCTGGA GAGATCCTGCTGTTCAGGAAACATACAAGAGAAGAGAGGAATTGCATAATCTTCCTGATGTCACTAAATATTTCTTAGAT CGGGTATGTCTTTACCATTTTTATCACTTTGTCTTCTAGAGAAGTATTTGGTTGCTTTATCTTGTATGTTCCATTGCAGT TGTGCATGTGAGCATATGATTGTTGTTATGTTACAACTAAATATTTGTCCATTGAACTTCTTTTGTTTTTGCCTTTTCCA TTCTGGAGTTAATTCAATGCAGCAAGCCTCAGTGCTCTCCTGAACTGAACCAACTATTACTTCACCTTATCTATTATGAT GAACTTACAAAAAGAGAGTGAAACACTAGAGCTGAGAGAAAGGGGTGTTAGTTACATTATTATTGTTTCAATGTAGAAAA TTTGAATTTTAGATGTATGGAAGAGGAGAAAATGTACCTTCACAAGAAACGGTGTTTGCAAAGAAGAAGCATGAATCTGT AAATTCTATTGGCTAGTAACAATTATCTGGAAATGTCATTTTTCCCATTTTGTTTTTCCTTGAAAAGGAAGTGCTTGAAA AGTTGCTATTTATCTAAACAACTTAGAAGGGCTGAAGGGTTAAATTAGTTCCTTGCAAGAAATGAATGAACTTCTGATGG ACTTTACAGTTAATCTAAATCACATCTAATTTGCGCTTTTGTTTGGTAGCATTAATTTGAACATTTACTACTATGAAGTC TTAGCTCATTTTTATAATTGGGGAAGTTTTTTGTTGCATATTGTCATTCTTATTCTTCATGAAATTAGTGACGGAGTTAG TATCAACATGATTTCTATTTTAATTTAGGCAAAAGTTTATTAAACTCACTTTCTATAAGGAGATATTCAATCTAATAACT AGCCTTGACTTGAGACTAAAATAATCTGAGTATTCGATATATCTTTGCATGAATGAGATATACAATATTATATTCAAAGG TTACGTAGTCAATATTGAAGCTTAGGGATTACAAAATCAGCTAATTAGGGAAAGCAGGGAAACTATGAAATAAGATCAAA ACAAAATCTGTACATAATCAATAATATAGTTACAGAATAATATTACAACACTCCCCCTCAGGATAAACATATAAATCGAA TGCATTTAGCTTAGAACATACGTATAGTATTATTAGGAATTGGATCAGAATACAAAGAACATTGATATTGACAGCAAAAC TCAATTACACTAGTTATTCAAGGGTCTTGGAACACTAAAACCTGATAACCATGTTCCTGTAAATAGACAATGATATCTAC AAGGGTCGCAATGATTCTTTTAATTGTCAACAATAGTAACTAGCTTGTTCTTTGCTGATTCCTCCTTTCTTATTCAGACC GGTTCCATTCTCCTTTTATAGGATCCACTTATGCTCATAAGTGGTTGGGCTTGACCCATTTCTCCATAATTTTGACTGAG CCACTTGAATCCCAAAAAAATGATTCAAAGGACCTAAGTCCTGAAACTGCTGAGATAAGTGTTCTTAAGGGCTTGAAGCC CTCATGATCATCACCTGTAATCACAATATCCTCCACATAAACTATACATATTTTTATTTGAATATAAGCATTTAAAGAAG ACATACTATATAGTAAATCTTCGCTAAACCAACCCAACAAAGTTTGAATTGTTTTAGGCCATATTGGGACTTCTGGAATT TGCATTCAAGACCTCAGCCTCTTGCGCAACAAAGCTGGGGTAGACCTCCTCCAGGTCACCATGTATGAAAGCAATTTTAA TATCTAACTGAAATAAGGGTTGTGATTTATGCAGCCGTAGCTAAAAAGAGATGAACTTAGACCATCTTCCCCACTGGAGA GTACATATTATTTTAATCCAAACCAAACATGTGTGTATCCTTTAGCCACAAAACAAACTTTCAAGCGATCCATCTTGTCT TTTGCTTTTGCTGATCTATTCTAGGTTGAATATGAGGGTAGTTTGCTAACTTCGTTCAAATATATTTTTCTTTCTTTTGT TCTTTTGATCTTTTGATTTGTCATTCTTTTCTGGCTATTAATTTAAAGAACAGCCTTTAAAAATATTGACTTTTTGTCCT ATCATTGTGAGGTCTAATCACGTGTGATCCTATACAGGCAATGGAAATATCAAGCAATGAGTATGAACCTTCGGATAAGG ATGTATTATATGCTGAAGGAGTCGCTCAGAGCAATGGTCTTGCCTTCATGGAATTCTCATTTGATGATAGGAGTCCCATG TCTGAGATATACAGCGGAAACATAAGTTCCCAAACTCCTTTAATCAAGTAAACCATTCTCTTTCACCTCCTTTACTCTTA TTTTGTGGAAGCTTCGTAAAATGTTTTTAACTCCTTCACATTGTCACTGTCTCAGATATCAACTGATTCGCATAAATTCA AAGGGACTGCGCGATGGCTGCAAGTGGTTGCAAATGTTTGAAGATGTGAGGATCGTCATATTTTGTGTTTCCTTAAGTGA CTATGACCAAATGTGGCCAACTAGTACCGGTCAACTTCAAAACAAATTGCTGGCAAGTAGGGATCTTTTTGAGAGTCTGG TGAGGCATCCTTGTTTTCAAGATACCCCTTTTGTGCTTGTGCTAAATAAATATGATGCCTTTGAAGACAAGATAAGCAAA GTTCCTTTGTCTACTTGTGAGTGGTTTGCGGACTTCTGTCCTGTGAGACCCCATCACAACAGTCATGCCCTAGCACAACA AGCATATTACTATGTAGCTGTGAGATTCAAGGAACTTTATCATTCCTTGACCAGCCAGAAGTTGTTTGTGGGGCAAACTC GAGCTCGGGATCGCGCCTCAGTTGATGAGGCATTCAAGTACATAAGGGAGGTCATCAAATGGGAGGATGAGAAGGATGAT GATGTGTATGAAATCAATCTGGAAGAGTCATATTACAGTACAGAAATGAGTTCTTCCCCATTCGTCAGGCAGGAATGAAT TTCTAACTCTTGATAGCCCTTGAGACTAAATGATCTCATGTGGATATTAAGTGATAAGCAAGTCTCGCTGCTCCTAAGAA TCCAAAGAATTGTAGGAGCATTGCATTTGTGAAGGACTGAGAGGTCAGTTGATTTTGTTGTAGGGTCTTCTTGATCAGGT TTCTAATGATTTTTTCCTCATCATAAATAAGCTGATTTGATTGAGAGGTTGTAAATTCAGAGGTGATTTGTTTTCTGTAC AGCTTATATTGATAATTTTCCAGCTTAAATTTTAAAAATAAGAAAAGGAAAATTATTTTTTTCCCGTTATTATTTAAGTG AGCCATTGGGTCCATTGGTCACCAAGATAAATACTAAAAA
Download Genomic Sequence

CDS sequence (LotjaGi2g1v0191500.3) extracted from Lotus japonicus Gifu v1.2 CDS.

ATGTTCAATGCCCGCGAGACACCCATTTCTGGGTTTATGATGATGGCTCTTATGAGGAAGAAGGCCAAAATAATATTAAA GGGAACATATGGGGAAAGGCAGGCGTCCACTCGTTTGATTTGTTCATTATGCTCATTGCCTGTACCACCTACTAATCCTC CTGGGGTCAAAGATAATCTGACTAACTATTCAACAAGGTCTGTGCCTGAGTATTTAGAGCAAGGTAGAGTTCAGAAACTA TTGTTGTTTGGTATGGAAGGATCTGGAACAGCCACTCTGTTTAAACAGGCCAAGTTTTTATATGGAAACAAGTTTTCTCC AGAAGAGTTGCAAAACATTAAACTCATGATTCAAAGCAATATGTACAAGTATCTCAGCATTCTGCTTGAAGGACGAGAGC AGTTTGAAGAGGAAGCTCTGGCAGAGAAAGAATGTGCCTCGTTAGAAGATGAAGAATCTGGACCTGAAAGAGCAGCTGAG GAAAACAAACCAACCATTTACTCGATCAATCAAAGACTCAAGCATTTTTCTGACTGGTTGCTGGATATTATGGCTACGGG GGATTTGGAGGCTTTCTTCCCTGCTGCTACGCGTGAGTATGCTCCTATGGTAGAGGAGATCTGGAGAGATCCTGCTGTTC AGGAAACATACAAGAGAAGAGAGGAATTGCATAATCTTCCTGATGTCACTAAATATTTCTTAGATCGGGCAATGGAAATA TCAAGCAATGAGTATGAACCTTCGGATAAGGATGTATTATATGCTGAAGGAGTCGCTCAGAGCAATGGTCTTGCCTTCAT GGAATTCTCATTTGATGATAGGAGTCCCATGTCTGAGATATACAGCGGAAACATAAGTTCCCAAACTCCTTTAATCAAAT ATCAACTGATTCGCATAAATTCAAAGGGACTGCGCGATGGCTGCAAGTGGTTGCAAATGTTTGAAGATGTGAGGATCGTC ATATTTTGTGTTTCCTTAAGTGACTATGACCAAATGTGGCCAACTAGTACCGGTCAACTTCAAAACAAATTGCTGGCAAG TAGGGATCTTTTTGAGAGTCTGGTGAGGCATCCTTGTTTTCAAGATACCCCTTTTGTGCTTGTGCTAAATAAATATGATG CCTTTGAAGACAAGATAAGCAAAGTTCCTTTGTCTACTTGTGAGTGGTTTGCGGACTTCTGTCCTGTGAGACCCCATCAC AACAGTCATGCCCTAGCACAACAAGCATATTACTATGTAGCTGTGAGATTCAAGGAACTTTATCATTCCTTGACCAGCCA GAAGTTGTTTGTGGGGCAAACTCGAGCTCGGGATCGCGCCTCAGTTGATGAGGCATTCAAGTACATAAGGGAGGTCATCA AATGGGAGGATGAGAAGGATGATGATGTGTATGAAATCAATCTGGAAGAGTCATATTACAGTACAGAAATGAGTTCTTCC CCATTCGTCAGGCAGGAATGA
Download CDS Sequence

Protein sequence (LotjaGi2g1v0191500.3) extracted from Lotus japonicus Gifu v1.2 Proteins.

MFNARETPISGFMMMALMRKKAKIILKGTYGERQASTRLICSLCSLPVPPTNPPGVKDNLTNYSTRSVPEYLEQGRVQKL LLFGMEGSGTATLFKQAKFLYGNKFSPEELQNIKLMIQSNMYKYLSILLEGREQFEEEALAEKECASLEDEESGPERAAE ENKPTIYSINQRLKHFSDWLLDIMATGDLEAFFPAATREYAPMVEEIWRDPAVQETYKRREELHNLPDVTKYFLDRAMEI SSNEYEPSDKDVLYAEGVAQSNGLAFMEFSFDDRSPMSEIYSGNISSQTPLIKYQLIRINSKGLRDGCKWLQMFEDVRIV IFCVSLSDYDQMWPTSTGQLQNKLLASRDLFESLVRHPCFQDTPFVLVLNKYDAFEDKISKVPLSTCEWFADFCPVRPHH NSHALAQQAYYYVAVRFKELYHSLTSQKLFVGQTRARDRASVDEAFKYIREVIKWEDEKDDDVYEINLEESYYSTEMSSS PFVRQE
Download Protein Sequence

Domain prediction

Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.

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Domains

Sorting

Prediction algorithm Identifier Start End Length E-value InterPro ID
PANTHER
PTHR10218:SF317
34 479 446 3.0E-261 –
PANTHER
PTHR10218
34 479 446 3.0E-261
IPR001019
SMART
SM00275
62 463 402 9.1E-15
IPR001019
ProSiteProfiles
PS51882
76 464 389 56.055 –
Pfam
PF00503
76 453 378 1.0E-65
IPR001019
SUPERFAMILY
SSF52540
77 457 381 1.56E-23
IPR027417
CDD
cd00066
78 456 379 5.22403E-81
IPR001019
Gene3D
G3DSA:3.40.50.300
79 440 362 5.4E-77 –
PRINTS
PR00318
79 94 16 8.2E-6
IPR001019
SUPERFAMILY
SSF47895
105 255 151 3.01E-22
IPR011025
Gene3D
G3DSA:1.10.400.10
106 260 155 5.4E-77
IPR011025
PRINTS
PR00318
317 345 29 8.2E-6
IPR001019
PRINTS
PR00318
365 374 10 8.2E-6
IPR001019

Gene function (GO predictions)

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003924
Molecular function GTPase activity Catalysis of the reaction: GTP + H2O = GDP + phosphate.
Subterm of
GO:0007165
Biological process Signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
Subterm of
Part of
GO:0007186
Biological process G protein-coupled receptor signaling pathway A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
Subterm of
GO:0019001
Molecular function Guanyl nucleotide binding Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate.
Subterm of
GO:0031683
Molecular function G-protein beta/gamma-subunit complex binding Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits.
Subterm of

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Expression data

Expression pattern

Expression pattern of LotjaGi2g1v0191500.3, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.

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