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| Field | Value |
|---|---|
| Gene ID | LotjaGi2g1v0352700 |
| Transcript ID | LotjaGi2g1v0352700.2 |
| Related isoforms 1 | |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | 3-hydroxy-3-methylglutaryl coenzyme A reductase; TAIR: AT1G76490.1 hydroxy methylglutaryl CoA reductase 1; Swiss-Prot: sp|P29057|HMDH1_HEVBR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1; TrEMBL-Plants: tr|A0A075EC73|A0A075EC73_ASTME 3-hydroxy-3-methylglutaryl coenzyme A reductase; Found in the gene: LotjaGi2g1v0352700 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr2:82875128..82878736) extracted from Lotus japonicus Gifu genome v1.2.
ATGGACGTTCGCCGGCGACCCACCAACGCCGCCGTCGTGCGTCCACCTCCCGCCGCCAAACACCCAAAAATGAAGAAGAA TGAATCACAGACATCTCTGTACGTCACCAACACCGTCTTCTTCACTCTCTTCTTCTCCGTCGCCTACTTCCTCCTCCACC GTTGGCGCGAGAAGATCCGCACCTCCACCCCTCTCCACTTCGTCACGGTTTCCGAGATCGCCGCCATCCTCTCCCTCTTC GCTTCCGTCATCTACCTCACCTCCTTCTTCGGCATTGGCTTCATCCTCCACCCCTTCGCCGCTTCCCGCCCCGTCCCCGG TGAAGACGACGACGAAGAAGAACTCGTCGCCGACATTTCCCCCTGCCTCAACAATCTCCCCCCGCCGCCGCTCAAAATCG CCAACGGCAACGGCAACGGCAAATCCCTCTCACCTCCGTCGCCGACGGCGACAACAACTACTCTGTCCTCGGAGGACGAG GAGGTTATCCGGGAGGTGGTGTCGGGGTCAATCCCGTCGTACTCGCTGGAAACGAAGCTCGGGGATTGCCGGCGGGCGGC GGTGATTCGTCACGAGGCGGTGGAGAGGGTGGTGGGGAGGTCGCTGGAGGGTTTACCGGTGGAAGGGTTTGATTATGAGT CGATATTGGGGCAGTGCTGTGAGATGCCGATTGGGTTCATTCAGATTCCGGTTGGGGTGGCAGGGCCGCTGTTACTCGAC GGGAAAGAGTACACCGTCCCCATGGCCACCACGGAGGGTTGTCTGGTGGCGAGCACCAACAGAGGCTGCAAGGCTATTTA CGTTTCCGGTGGTGCTTCCGCGGTGCTCCTCCGTGATGGCATGACCAGGGCACCTGTTGTCAGGTTCAGCTCCGCCAAAA GGGCTGCTCAGTTGAAGTTCTACTTGGAAGACCCTGAGAATTTTGATTCTCTCGCTCTCACTTTCAACAAGTAAATTTTC AATTCCAATACCCTTTTGAATTCTTAAAAAAATTTATGATATGATGATAGTAGTAAAGAGTAAAGACTATAGAGTAAAGA CAAAAGAGTGTTTGAATTTTCTGTGTTTGGAGAATTTGGTGAAGGAAATGGACAAATGAATGTTAGCTTTTTTGGTGATT GTGGTTGGCTTAATGGGTTGTAGTTGTTGTGTTGTGTTGTTAATGGTTGACTGAGTCTGTTGTTATGTGCAGGTCAAGTA GGTTTGCAAAGTTGCAGAGTATTAAGCCTGCAATAGTAGGCAAGAATTTGTACATTAGATTCTGTTGCAGCACTGGAGAT GCCATGGGGATGAACATGGTTTCCAAAGGTGTCCAAAACGTACTTGCTTTCCTTCAAGAGGACTTCCCTGACATGGATGT TATTGGCATTTCTGGTAAATTTTACATCACATCATCTTTGCATTTTTAACTTGTAGGTCAAACTAGTTGCTATAATTGAA GATTGAAGTGAGCAAGTAACTATAGTATCCTAGATTTTCATAGATTAAGATTAGGATGCAATTTAATTAAATTTACTCAA TGATAAATATTACCATTACTTATTTAATCTTAAATTCAATTCAATTTAGAGCATGTCTGAATTAGCTTTTAGCAATTCAG AATAATTTCTCTCCTTCCAGTACCATGTTTGGATCGACTTATCTTTTCTTAGAATCAATTCTGCGGTCATGGTATCTTGT TCCCTGAATTGATTATGACTTTTATATCAATTAGATAGAAGTATTTCTAAATATGTAATCACTAAGTGCCTCAGTGGCTT CTCCTCCATTGTGATTTGGAGGTTTAAAGTGAAATTTTATTGTTAATCCAAACACGCACTTAGTGCATGTGTGTTTAATC TGTTGAATTTGGTTATCAGGAAATTTCTGCTCGGACAAGAAAGCAGCAGCTGTGAACTGGATTGAAGGGCGTGGTAAGTC TGTGGTGTGCGAGGCCGTAATTAAGGAAGAGGTGGTGAAGAAAGTGTTGAAGACCAGCGTGGAGGCCTTGGTTGAGCTTA ACATGCTCAAAAACCTTACTGGCTCAGCCGTGGCAGGTGCTCTTGGTGGCTTCAATGCCCATGCTAGCAATATTGTTTCT GCTGTCTACTTGGCCACGGGTCAGGATCCTGCTCAGAATGTGGAGAGTTCTCACTGCATCACCATGATGGAGGCCGTTAA CGATGGCAGAGATCTTCACGTCTCCGTCACCATGCCTTCCATTGAGGTACAATTACTTAATTTGGTCTCAAATTAAACAT GATTTATCTCTGATTTTCTATAACAACAATGTTATGTCCACCTTCAAGAATTGAGTGTCAACTAGTTTACACCTTATGCA GTGTTACTTTTTCACTTAATCATGTAAGAAATAAAATAGAATAAAATCTCTCAAATTCAGAATGGATGTAGGTATTGCTT GTTTTAGGTGTGGAATTGTCATTATAGTCTCTATAATCCGTTGGGGGTAAACAAATTCGACAGTTAATGCGAGTTGTAGT AGTAATACCATTGAAGACGAGTCCTTTTTGTATTCATCTATCTATATTATTGGTAAGGCACGTGATAGTGATCCAGTTTT TGGTCCCTTGCCTGTCTCTGAACCTGTCCACATTACTGTCAAAGGGAGAGCTGACATCATCAAAATCCATGGCTGCAAGA CAACCTAACATTCAGTGCCTTAAAGATTTAAATCCGAGAGTAGTTTGATTAGCTATTAGATTATTCTTTCCCCTACAATC TCATGTTTTTTTAATTATCAATGTATAGAATATGCTTATTGTGGAGCTAAGCAGACTGTGTTGCTCAGTCAGTCCCTCCC TTGGGACCAAGCTCAACTGAACTTTATTGATTTATTCTCTCTTTTCTTATTTACTCTGGCCATTATATGCAAGACCTGGT CCCCTAGCACAGATCTCATTTACACCCAGCAGACAAAGTTTGCTCAGACTCCAGTTAGACCTCAGAGTCCTTTATTTCCT AGTGCCTTAAATACAGGGCTAGATTCAGTTTGATCACTCTCTTTAATATTTGCCCCATTGTCTTTTCTGTTTATAATATT CTCAATCTGATTCTACAATTGAGTCTAAAGCTAAAATTAATTTTGAGGACAATCTTCTGTGAGTTGTTGGGTGTCAGAAT TGATTCTGAAGGAAGAGAAGTTGATGTGAAGATAATGTAAGTTTAATGATAAAAGGACTTCAAATCAAATGAGACACCTA CCTAGTTAGAAGCCATTCATATCCCAGTGTGTCTTAATAAAGTAAATTATTTGAGTCTAACCTGCCTCAGATCTCTCTTT TCGCAATAATATTTTGATACTGATACATTAGCATAATGACAAGGTCACTTTTTTATGAGTTTGATTCATGTATTGTTTGA ATGGAGCAGGTGGGCACAGTTGGTGGGGGCACACAGCTCGCATCTCAATCAGCATGTCTTAATTTACTTGGTGTGAAGGG TGCCAGCAAGGAGTTGCCGGGTGCGAATTCTAGGCAACTGGCAACTATAATAGCTGGCGCAGTCCTCGCCGGGGAACTCT CCCTCATGTCTGCAATTGCAGCAGGGCAGCTTGTGAAGAGCCACATGAAATACAACAGGTCTAGCAAGGATATCACCAAA GTTGCATGA
CDS sequence (LotjaGi2g1v0352700.2) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGGACGTTCGCCGGCGACCCACCAACGCCGCCGTCGTGCGTCCACCTCCCGCCGCCAAACACCCAAAAATGAAGAAGAA TGAATCACAGACATCTCTGTACGTCACCAACACCGTCTTCTTCACTCTCTTCTTCTCCGTCGCCTACTTCCTCCTCCACC GTTGGCGCGAGAAGATCCGCACCTCCACCCCTCTCCACTTCGTCACGGTTTCCGAGATCGCCGCCATCCTCTCCCTCTTC GCTTCCGTCATCTACCTCACCTCCTTCTTCGGCATTGGCTTCATCCTCCACCCCTTCGCCGCTTCCCGCCCCGTCCCCGG TGAAGACGACGACGAAGAAGAACTCGTCCCTCCGTCGCCGACGGCGACAACAACTACTCTGTCCTCGGAGGACGAGGAGG TTATCCGGGAGGTGGTGTCGGGGTCAATCCCGTCGTACTCGCTGGAAACGAAGCTCGGGGATTGCCGGCGGGCGGCGGTG ATTCGTCACGAGGCGGTGGAGAGGGTGGTGGGGAGGTCGCTGGAGGGTTTACCGGTGGAAGGGTTTGATTATGAGTCGAT ATTGGGGCAGTGCTGTGAGATGCCGATTGGGTTCATTCAGATTCCGGTTGGGGTGGCAGGGCCGCTGTTACTCGACGGGA AAGAGTACACCGTCCCCATGGCCACCACGGAGGGTTGTCTGGTGGCGAGCACCAACAGAGGCTGCAAGGCTATTTACGTT TCCGGTGGTGCTTCCGCGGTGCTCCTCCGTGATGGCATGACCAGGGCACCTGTTGTCAGGTTCAGCTCCGCCAAAAGGGC TGCTCAGTTGAAGTTCTACTTGGAAGACCCTGAGAATTTTGATTCTCTCGCTCTCACTTTCAACAAGTCAAGTAGGTTTG CAAAGTTGCAGAGTATTAAGCCTGCAATAGTAGGCAAGAATTTGTACATTAGATTCTGTTGCAGCACTGGAGATGCCATG GGGATGAACATGGTTTCCAAAGGTGTCCAAAACGTACTTGCTTTCCTTCAAGAGGACTTCCCTGACATGGATGTTATTGG CATTTCTGGAAATTTCTGCTCGGACAAGAAAGCAGCAGCTGTGAACTGGATTGAAGGGCGTGGTAAGTCTGTGGTGTGCG AGGCCGTAATTAAGGAAGAGGTGGTGAAGAAAGTGTTGAAGACCAGCGTGGAGGCCTTGGTTGAGCTTAACATGCTCAAA AACCTTACTGGCTCAGCCGTGGCAGGTGCTCTTGGTGGCTTCAATGCCCATGCTAGCAATATTGTTTCTGCTGTCTACTT GGCCACGGGTCAGGATCCTGCTCAGAATGTGGAGAGTTCTCACTGCATCACCATGATGGAGGCCGTTAACGATGGCAGAG ATCTTCACGTCTCCGTCACCATGCCTTCCATTGAGGTGGGCACAGTTGGTGGGGGCACACAGCTCGCATCTCAATCAGCA TGTCTTAATTTACTTGGTGTGAAGGGTGCCAGCAAGGAGTTGCCGGGTGCGAATTCTAGGCAACTGGCAACTATAATAGC TGGCGCAGTCCTCGCCGGGGAACTCTCCCTCATGTCTGCAATTGCAGCAGGGCAGCTTGTGAAGAGCCACATGAAATACA ACAGGTCTAGCAAGGATATCACCAAAGTTGCATGA
Protein sequence (LotjaGi2g1v0352700.2) extracted from Lotus japonicus Gifu v1.2 Proteins.
MDVRRRPTNAAVVRPPPAAKHPKMKKNESQTSLYVTNTVFFTLFFSVAYFLLHRWREKIRTSTPLHFVTVSEIAAILSLF ASVIYLTSFFGIGFILHPFAASRPVPGEDDDEEELVPPSPTATTTTLSSEDEEVIREVVSGSIPSYSLETKLGDCRRAAV IRHEAVERVVGRSLEGLPVEGFDYESILGQCCEMPIGFIQIPVGVAGPLLLDGKEYTVPMATTEGCLVASTNRGCKAIYV SGGASAVLLRDGMTRAPVVRFSSAKRAAQLKFYLEDPENFDSLALTFNKSSRFAKLQSIKPAIVGKNLYIRFCCSTGDAM GMNMVSKGVQNVLAFLQEDFPDMDVIGISGNFCSDKKAAAVNWIEGRGKSVVCEAVIKEEVVKKVLKTSVEALVELNMLK NLTGSAVAGALGGFNAHASNIVSAVYLATGQDPAQNVESSHCITMMEAVNDGRDLHVSVTMPSIEVGTVGGGTQLASQSA CLNLLGVKGASKELPGANSRQLATIIAGAVLAGELSLMSAIAAGQLVKSHMKYNRSSKDITKVA
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | 1 | 544 | 544 | 0.0 | – | |
| Phobius | 1 | 32 | 32 | - | – | |
| MobiDBLite | 1 | 27 | 27 | - | – | |
| PANTHER | 1 | 544 | 544 | 0.0 | ||
| TMHMM | 30 | 52 | 23 | - | – | |
| Phobius | 33 | 52 | 20 | - | – | |
| Phobius | 53 | 72 | 20 | - | – | |
| Phobius | 73 | 96 | 24 | - | – | |
| TMHMM | 73 | 95 | 23 | - | – | |
| Phobius | 97 | 501 | 405 | - | – | |
| MobiDBLite | 105 | 128 | 24 | - | – | |
| Gene3D | 120 | 201 | 82 | 2.5E-19 | ||
| SUPERFAMILY | 123 | 524 | 402 | 4.58E-106 | ||
| ProSiteProfiles | 131 | 535 | 405 | 139.731 | ||
| TIGRFAM | 131 | 535 | 405 | 6.6E-162 | ||
| CDD | 132 | 535 | 404 | 0.0 | ||
| Pfam | 160 | 535 | 376 | 4.7E-144 | ||
| PRINTS | 191 | 212 | 22 | 3.6E-86 | ||
| Gene3D | 202 | 522 | 321 | 4.5E-145 | ||
| PRINTS | 218 | 238 | 21 | 3.6E-86 | ||
| Gene3D | 252 | 368 | 117 | 4.5E-145 | ||
| SUPERFAMILY | 252 | 368 | 117 | 2.62E-46 | ||
| PRINTS | 309 | 327 | 19 | 3.6E-86 | ||
| ProSitePatterns | 311 | 325 | 15 | - | ||
| PRINTS | 349 | 374 | 26 | 3.6E-86 | ||
| PRINTS | 400 | 426 | 27 | 3.6E-86 | ||
| PRINTS | 454 | 475 | 22 | 3.6E-86 | ||
| ProSitePatterns | 466 | 473 | 8 | - | ||
| Phobius | 502 | 527 | 26 | - | – | |
| ProSitePatterns | 520 | 533 | 14 | - | ||
| Phobius | 528 | 544 | 17 | - | – |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Hydroxymethylglutaryl-CoA reductase (NADPH) activity | Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH. | ||
| Molecular function | Protein binding | Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). | ||
| Biological process | Isoprenoid biosynthetic process | The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. | ||
| Biological process | Coenzyme A metabolic process | The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. | ||
| Molecular function | Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP. | ||
| Molecular function | Coenzyme binding | Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
Expression pattern of LotjaGi2g1v0352700.2, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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