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IPR000358 is a Ribonucleotide reductase small subunit family.
<p>Ribonucleotide reductase (RNR), also known as ribonucleoside diphosphate reductase, ([ec:1.17.4.1]) [[cite:PUB00000559], [cite:PUB00005164]] catalyses the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides:<reaction> 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H<sub>2</sub>O = ribonucleoside diphosphate + reduced thioredoxin</reaction> </p> <p>RNR provides the precursors necessary for DNA synthesis. RNRs divide into three classes on the basis of their metallocofactor usage. Class I RNRs, found in eukaryotes, bacteria, bacteriophage and viruses, use a diiron-tyrosyl radical, Class II RNRs, found in bacteria, bacteriophage, algae and archaea, use coenzyme B12 (adenosylcobalamin, AdoCbl). Class III RNRs, found in anaerobic bacteria and bacteriophage, use an FeS cluster and S-adenosylmethionine to generate a glycyl radical. Many organisms have more than one class of RNR present in their genomes.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Deoxyribonucleotide biosynthetic process | The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: ribonucleoside-diphosphate reductase small chain-like [Cicer arietinum] gi|502164888|ref|XP_004513312.1| | 14 | ||
| – | 14 | |||
| – | PREDICTED: ribonucleoside-diphosphate reductase small chain-like [Glycine max] gi|356558708|ref|XP_003547645.1| | 16 | ||
| – | PREDICTED: ribonucleoside-diphosphate reductase small chain-like [Glycine max] gi|356571527|ref|XP_003553928.1| | 14 | ||
| – | PREDICTED: ribonucleoside-diphosphate reductase small chain-like [Cicer arietinum] gi|502164888|ref|XP_004513312.1| | 14 | ||
| – | PREDICTED: ribonucleoside-diphosphate reductase small chain-like [Glycine max] gi|356558708|ref|XP_003547645.1| | 9 | ||
| – | Ribonucleotide reductase small subunit [Glycine max] gi|351721787|ref|NP_001237733.1| | 17 | ||
| – | RecName: Full=Ribonucleoside-diphosphate reductase small chain; AltName: Full=Ribonucleoside-diphosphate reductase R2 subunit; AltName: Full=Ribonucleotide reductase small subunitgi|1044912|emb|CAA63194.1| ribonucleotide reductase R2 [Nicotiana tabacum] gi|1710401|sp|P49730.1|RIR2_TOBAC | 7 | ||
| – | Ribonucleoside-diphosphate reductase; TAIR: AT3G27060.1 Ferritin/ribonucleotide reductase-like family protein; Swiss-Prot: sp|P49730|RIR2_TOBAC Ribonucleoside-diphosphate reductase small chain; TrEMBL-Plants: tr|A0A0R4J5J3|A0A0R4J5J3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0279100 | 15 | ||
| – | Ribonucleoside-diphosphate reductase; TAIR: AT3G27060.1 Ferritin/ribonucleotide reductase-like family protein; Swiss-Prot: sp|P49730|RIR2_TOBAC Ribonucleoside-diphosphate reductase small chain; TrEMBL-Plants: tr|A0A0R4J5J3|A0A0R4J5J3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0376800 | 15 | ||
| – | Ribonucleoside-diphosphate reductase; TAIR: AT3G27060.1 Ferritin/ribonucleotide reductase-like family protein; Swiss-Prot: sp|P49730|RIR2_TOBAC Ribonucleoside-diphosphate reductase small chain; TrEMBL-Plants: tr|A0A0L9U8J2|A0A0L9U8J2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0606800 | 15 | ||
| – | Ribonucleoside-diphosphate reductase small chain; TAIR: AT3G23580.1 ribonucleotide reductase 2A; Swiss-Prot: sp|P50651|RIR2A_ARATH Ribonucleoside-diphosphate reductase small chain A; TrEMBL-Plants: tr|I3SPM1|I3SPM1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0351000 | 17 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 8.33 |