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IPR012348

Description

IPR012348 is a Ribonucleotide reductase-like.

<p>The R2 protein of ribonucleotide reductase catalyses the reduction of all four ribonucleotides to deoxyribonucleotides for use in DNA synthesis. This catalysis involves generating and storing a tyrosyl radical, which is essential for ribonucleotide reduction. The crystal structure consists of a core of four helices in a closed bundle with a left-handed twist and one crossover connection, and a bimetal-ion centre in the middle of the bundle [[cite:PUB00016337]].</p> <p>This entry represents proteins that are structurally related to the R2 protein of class I ribonucleotide reductase, including the alpha and beta subunits of methane monooxygenase, and delta 9-stearoyl-acyl carrier protein desaturase [[cite:PUB00016338]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
Biological process Oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

Associated Lotus transcripts 21

Transcript Name Description Predicted domains Domain count
PREDICTED: ribonucleoside-diphosphate reductase small chain-like [Cicer arietinum] gi|502164888|ref|XP_004513312.1| 14
14
PREDICTED: ribonucleoside-diphosphate reductase small chain-like [Glycine max] gi|356558708|ref|XP_003547645.1| 16
Acyl-[acyl]-carrier-protein] gi|67633223|gb|AAY78547.1| 16
PREDICTED: acyl-[acyl]-carrier-protein] gi|502124091|ref|XP_004498381.1| 11
PREDICTED: ribonucleoside-diphosphate reductase small chain-like [Glycine max] gi|356571527|ref|XP_003553928.1| 14
PREDICTED: ribonucleoside-diphosphate reductase small chain-like [Cicer arietinum] gi|502164888|ref|XP_004513312.1| 14
PREDICTED: ribonucleoside-diphosphate reductase small chain-like [Glycine max] gi|356558708|ref|XP_003547645.1| 9
Acyl-[acyl]-carrier-protein] gi|67633223|gb|AAY78547.1| 16
Ribonucleotide reductase small subunit [Glycine max] gi|351721787|ref|NP_001237733.1| 17
RecName: Full=Ribonucleoside-diphosphate reductase small chain; AltName: Full=Ribonucleoside-diphosphate reductase R2 subunit; AltName: Full=Ribonucleotide reductase small subunitgi|1044912|emb|CAA63194.1| ribonucleotide reductase R2 [Nicotiana tabacum] gi|1710401|sp|P49730.1|RIR2_TOBAC 7
Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT1G43800.1 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q84VY3|STAD6_ARATH Stearoyl-[acyl]-carrier-protein] 9-desaturase 6, chloroplastic; TrEMBL-Plants: tr|A0A072VEM1|A0A072VEM1_MEDTR Stearoyl-acyl-carrier desaturase; Found in the gene: LotjaGi1g1v0168700 11
Ribonucleoside-diphosphate reductase; TAIR: AT3G27060.1 Ferritin/ribonucleotide reductase-like family protein; Swiss-Prot: sp|P49730|RIR2_TOBAC Ribonucleoside-diphosphate reductase small chain; TrEMBL-Plants: tr|A0A0R4J5J3|A0A0R4J5J3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0279100 15
Ribonucleoside-diphosphate reductase; TAIR: AT3G27060.1 Ferritin/ribonucleotide reductase-like family protein; Swiss-Prot: sp|P49730|RIR2_TOBAC Ribonucleoside-diphosphate reductase small chain; TrEMBL-Plants: tr|A0A0R4J5J3|A0A0R4J5J3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0376800 15
Ribonucleoside-diphosphate reductase; TAIR: AT3G27060.1 Ferritin/ribonucleotide reductase-like family protein; Swiss-Prot: sp|P49730|RIR2_TOBAC Ribonucleoside-diphosphate reductase small chain; TrEMBL-Plants: tr|A0A0L9U8J2|A0A0L9U8J2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0606800 15
Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT2G43710.1 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q42807|STAD_SOYBN Stearoyl-[acyl]-carrier-protein] 9-desaturase, chloroplastic; TrEMBL-Plants: tr|Q4PZD4|Q4PZD4_LOTJA Acyl-[acyl]-carrier-protein] desaturase; Found in the gene: LotjaGi4g1v0068200 17
Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT2G43710.1 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q42807|STAD_SOYBN Stearoyl-[acyl]-carrier-protein] 9-desaturase, chloroplastic; TrEMBL-Plants: tr|Q4PZD4|Q4PZD4_LOTJA Acyl-[acyl]-carrier-protein] desaturase; Found in the gene: LotjaGi4g1v0068200 12
Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT2G43710.2 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q42807|STAD_SOYBN Stearoyl-[acyl]-carrier-protein] 9-desaturase, chloroplastic; TrEMBL-Plants: tr|Q4PZD4|Q4PZD4_LOTJA Acyl-[acyl]-carrier-protein] desaturase; Found in the gene: LotjaGi4g1v0068200 12
Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT2G43710.1 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q42807|STAD_SOYBN Stearoyl-[acyl]-carrier-protein] 9-desaturase, chloroplastic; TrEMBL-Plants: tr|Q4PZD4|Q4PZD4_LOTJA Acyl-[acyl]-carrier-protein] desaturase; Found in the gene: LotjaGi4g1v0068200 18
Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT2G43710.1 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q42807|STAD_SOYBN Stearoyl-[acyl]-carrier-protein] 9-desaturase, chloroplastic; TrEMBL-Plants: tr|Q4PZD4|Q4PZD4_LOTJA Acyl-[acyl]-carrier-protein] desaturase; Found in the gene: LotjaGi4g1v0068200 18
Ribonucleoside-diphosphate reductase small chain; TAIR: AT3G23580.1 ribonucleotide reductase 2A; Swiss-Prot: sp|P50651|RIR2A_ARATH Ribonucleoside-diphosphate reductase small chain A; TrEMBL-Plants: tr|I3SPM1|I3SPM1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0351000 17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 4.76