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IPR000674 is a Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead.
<p>Aldehyde oxidase ([ec:1.2.3.1]) catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase ([ec:1.1.1.204]) catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase ([ec:1.1.3.22]) activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.</p> <p>The aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain is an evolutionary conserved protein domain [[cite:PUB00005209], [cite:PUB00019122]].</p> <p>This entry includes also the a/b hammerhead domain of the Nicotine 6-hydroxylase ndhL that is involved in the degradation of nicotine [[cite:PUB00153681], [cite:PUB00015693]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: xanthine dehydrogenase 1-like isoform X2 [Cicer arietinum] gi|502081768|ref|XP_004486962.1| | 39 | ||
| – | Aldehyde oxidase; TAIR: AT3G43600.1 aldehyde oxidase 2; Swiss-Prot: sp|Q7G192|ALDO2_ARATH Indole-3-acetaldehyde oxidase; TrEMBL-Plants: tr|A0A1J7IPN3|A0A1J7IPN3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0059700 | 35 | ||
| – | Aldehyde oxidase; TAIR: AT3G43600.1 aldehyde oxidase 2; Swiss-Prot: sp|Q7G192|ALDO2_ARATH Indole-3-acetaldehyde oxidase; TrEMBL-Plants: tr|A0A1J7HQY2|A0A1J7HQY2_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0059700 | 13 | ||
| – | Aldehyde oxidase; TAIR: AT3G43600.1 aldehyde oxidase 2; Swiss-Prot: sp|Q7G192|ALDO2_ARATH Indole-3-acetaldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0059900 | 36 | ||
| – | Aldehyde oxidase; TAIR: AT3G43600.1 aldehyde oxidase 2; Swiss-Prot: sp|Q7G192|ALDO2_ARATH Indole-3-acetaldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0059900 | 36 | ||
| – | Aldehyde oxidase; TAIR: AT2G27150.1 abscisic aldehyde oxidase 3; Swiss-Prot: sp|Q7G9P4|ALDO3_ARATH Abscisic-aldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0060000 | 36 | ||
| – | Aldehyde oxidase; TAIR: AT2G27150.1 abscisic aldehyde oxidase 3; Swiss-Prot: sp|Q7G9P4|ALDO3_ARATH Abscisic-aldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0060000 | 31 | ||
| – | Aldehyde oxidase; TAIR: AT2G27150.1 abscisic aldehyde oxidase 3; Swiss-Prot: sp|Q7G9P4|ALDO3_ARATH Abscisic-aldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0060000 | 31 | ||
| – | Aldehyde oxidase; TAIR: AT2G27150.1 abscisic aldehyde oxidase 3; Swiss-Prot: sp|Q7G9P4|ALDO3_ARATH Abscisic-aldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0060000 | 36 | ||
| – | Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RE38|A0A0B2RE38_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100 | 36 | ||
| – | Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RM17|A0A0B2RM17_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100 | 30 | ||
| – | Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RM17|A0A0B2RM17_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100 | 29 | ||
| – | Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0R0G5H5|A0A0R0G5H5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0288100 | 36 | ||
| – | Xanthine dehydrogenase/oxidase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RM17|A0A0B2RM17_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100 | 20 | ||
| – | Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RM17|A0A0B2RM17_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100 | 30 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF56176 | SUPERFAMILY | 1 | 6.67 |