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IPR002888 is a [2Fe-2S]-binding.
<p>The [2Fe-2S] binding domain is found in a range of enzymes including dehydrogenases, oxidases and oxidoreductases.</p> <p>The aldehyde oxido-reductase (Mop) from the sulphate reducing anaerobic Gram-negative bacterium Desulfovibrio gigas is a homodimer of 907 amino acid residues subunits and is a member of the xanthine oxidase family. The protein contains a molybdopterin cofactor (Mo-co) and two different [2Fe-2S] centres. It is folded into four domains of which the first two bind the iron sulphur centres and the last two are involved in Mo-co binding. Mo-co is a molybdenum molybdopterin cytosine dinucleotide. Molybdopterin forms a tricyclic system with the pterin bicycle annealed to a pyran ring. The molybdopterin dinucleotide is deeply buried in the protein. The cis-dithiolene group of the pyran ring binds the molybdenum, which is coordinated by three more (oxygen) ligands [[cite:PUB00005209]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. | ||
| Molecular function | Metal ion binding | Interacting selectively and non-covalently with any metal ion. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: xanthine dehydrogenase 1-like isoform X2 [Cicer arietinum] gi|502081768|ref|XP_004486962.1| | 39 | ||
| – | Aldehyde oxidase; TAIR: AT3G43600.1 aldehyde oxidase 2; Swiss-Prot: sp|Q7G192|ALDO2_ARATH Indole-3-acetaldehyde oxidase; TrEMBL-Plants: tr|A0A1J7IPN3|A0A1J7IPN3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0059700 | 35 | ||
| – | Aldehyde oxidase; TAIR: AT3G43600.1 aldehyde oxidase 2; Swiss-Prot: sp|Q7G192|ALDO2_ARATH Indole-3-acetaldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0059900 | 36 | ||
| – | Aldehyde oxidase; TAIR: AT3G43600.1 aldehyde oxidase 2; Swiss-Prot: sp|Q7G192|ALDO2_ARATH Indole-3-acetaldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0059900 | 36 | ||
| – | Aldehyde oxidase; TAIR: AT2G27150.1 abscisic aldehyde oxidase 3; Swiss-Prot: sp|Q7G9P4|ALDO3_ARATH Abscisic-aldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0060000 | 36 | ||
| – | Aldehyde oxidase; TAIR: AT2G27150.1 abscisic aldehyde oxidase 3; Swiss-Prot: sp|Q7G9P4|ALDO3_ARATH Abscisic-aldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0060000 | 31 | ||
| – | Aldehyde oxidase; TAIR: AT2G27150.1 abscisic aldehyde oxidase 3; Swiss-Prot: sp|Q7G9P4|ALDO3_ARATH Abscisic-aldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0060000 | 31 | ||
| – | Aldehyde oxidase; TAIR: AT2G27150.1 abscisic aldehyde oxidase 3; Swiss-Prot: sp|Q7G9P4|ALDO3_ARATH Abscisic-aldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0060000 | 36 | ||
| – | Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RE38|A0A0B2RE38_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100 | 36 | ||
| – | Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RM17|A0A0B2RM17_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100 | 30 | ||
| – | Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RM17|A0A0B2RM17_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100 | 29 | ||
| – | Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0R0G5H5|A0A0R0G5H5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0288100 | 36 | ||
| – | Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RM17|A0A0B2RM17_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100 | 30 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF56176 | SUPERFAMILY | 1 | 7.69 |