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IPR001365 is a Adenosine deaminase domain.
<p>Adenosine deaminases ([ec:3.5.4.4]) are monomeric zinc dependent enzymes involved in purine metabolism. They are required for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. Adenosine deaminases convert adenosine to the related nucleoside inosine by the substitution of the amino group for a hydroxyl group. These enzymes are distantly related to AMP deaminases [[cite:PUB00000343]] as they share three regions of sequence similarities; these regions are centred on residues which are proposed to play an important role in the catalytic mechanism of these two enzymes.</p> <p>This entry also includes a group of adenine deaminases more related to the bacterial and eukaryotic adenosine deaminases than to Bacillus subtilis adenine deaminase and its bacterial homologues [[cite:PUB00059155]]. Adenine deaminase catalyses the hydrolytic deamination of adenine to hypoxanthine.</p> <p>This entry represents the main structural domain of adenosine deaminase proteins.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Deaminase activity | Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3). |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | AMP deaminase [Medicago truncatula] gi|357468881|ref|XP_003604725.1| | 7 | ||
| – | PREDICTED: AMP deaminase-like [Cicer arietinum] gi|502155011|ref|XP_004509928.1| | 14 | ||
| – | PREDICTED: adenosine deaminase-like protein-like [Glycine max] gi|356521975|ref|XP_003529625.1| | 9 | ||
| – | PREDICTED: adenosine deaminase-like protein-like [Glycine max] gi|356548979|ref|XP_003542876.1| | 7 | ||
| – | PREDICTED: adenosine deaminase-like protein-like [Glycine max] gi|356548979|ref|XP_003542876.1| | 7 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 20 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 18 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 20 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 20 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 20 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 20 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|A0A151RKB3|A0A151RKB3_CAJCA AMP deaminase; Found in the gene: LotjaGi4g1v0181600 | 18 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|A0A072U298|A0A072U298_MEDTR AMP deaminase; Found in the gene: LotjaGi4g1v0181600 | 10 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|Q84NP7|AMPD_ORYSJ Probable AMP deaminase; TrEMBL-Plants: tr|A0A1D6M2L3|A0A1D6M2L3_MAIZE Uncharacterized protein; Found in the gene: LotjaGi4g1v0181600 | 8 | ||
| – | Adenosine deaminase-like protein; TAIR: AT4G04880.1 adenosine/AMP deaminase family protein; Swiss-Prot: sp|Q0VC13|ADAL_BOVIN Adenosine deaminase-like protein; TrEMBL-Plants: tr|A0A151STV7|A0A151STV7_CAJCA Adenosine deaminase-like protein; Found in the gene: LotjaGi4g1v0353700 | 7 | ||
| – | Adenosine deaminase-like protein; TAIR: AT4G04880.1 adenosine/AMP deaminase family protein; Swiss-Prot: sp|Q6DHV7|ADAL_HUMAN Adenosine deaminase-like protein; TrEMBL-Plants: tr|I3SBE8|I3SBE8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0296100 | 7 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00443 | CDD | 1 | 6.25 |