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IPR006329 is a AMP deaminase.
<p>AMP-deaminase (AMPD) ([ec:3.5.4.6]) is a large, well-conserved eukaryotic protein that catalyses the hydrolytic deamination of adenosine monophosphate (AMP) to inosine monophosphate (IMP), and so plays an important role in purine and energy metabolism [[cite:PUB00070718], [cite:PUB00154422]]. This entry also includes inactive deaminases from yeast, which lack the conserved His residues essential for binding the catalytic zinc ion and the conserved residues important for substrate binding and catalysis.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | AMP deaminase activity | Catalysis of the reaction: AMP + H2O = IMP + NH3. | ||
| Biological process | IMP salvage | Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | AMP deaminase [Medicago truncatula] gi|357468881|ref|XP_003604725.1| | 7 | ||
| – | AMP deaminase [Medicago truncatula] gi|357468881|ref|XP_003604725.1| | 4 | ||
| – | PREDICTED: AMP deaminase-like [Cicer arietinum] gi|502155011|ref|XP_004509928.1| | 14 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|G7JQ45|G7JQ45_MEDTR AMP deaminase; Found in the gene: LotjaGi1g1v0156500_LC | 3 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 20 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 18 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 20 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 20 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 20 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 | 20 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|A0A151RKB3|A0A151RKB3_CAJCA AMP deaminase; Found in the gene: LotjaGi4g1v0181600 | 18 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|A0A072U298|A0A072U298_MEDTR AMP deaminase; Found in the gene: LotjaGi4g1v0181600 | 10 | ||
| – | AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|Q84NP7|AMPD_ORYSJ Probable AMP deaminase; TrEMBL-Plants: tr|A0A1D6M2L3|A0A1D6M2L3_MAIZE Uncharacterized protein; Found in the gene: LotjaGi4g1v0181600 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF51556 | SUPERFAMILY | 1 | 7.69 |