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IPR006650

Description

IPR006650 is a Adenosine/AMP deaminase active site.

<p>Adenosine deaminase ([ec:3.5.4.4]) catalyzes the hydrolytic deamination of adenosine into inosine and AMP deaminase ([ec:3.5.4.6]) catalyzes the hydrolytic deamination of AMP into IMP. It has been shown [[cite:PUB00000343]] that these two enzymes share three regions of sequence similarities; these regions are centred on residues which are proposed to play an important role in the catalytic mechanism of these two enzymes. This entry presents one of these regions, it contains two conserved aspartic acid residues that are potential active site residues.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process Purine ribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
Molecular function Deaminase activity Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3).

Associated Lotus transcripts 9

Transcript Name Description Predicted domains Domain count
PREDICTED: AMP deaminase-like [Cicer arietinum] gi|502155011|ref|XP_004509928.1| 14
AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 20
AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 18
AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 20
AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 20
AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 20
AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|I1JLC7|I1JLC7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0194500 20
AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|A0A151RKB3|A0A151RKB3_CAJCA AMP deaminase; Found in the gene: LotjaGi4g1v0181600 18
AMP deaminase; TAIR: AT2G38280.1 AMP deaminase, putative / myoadenylate deaminase; Swiss-Prot: sp|O80452|AMPD_ARATH AMP deaminase; TrEMBL-Plants: tr|A0A072U298|A0A072U298_MEDTR AMP deaminase; Found in the gene: LotjaGi4g1v0181600 10

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF51556 SUPERFAMILY 1 11.11