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IPR001441 is a Decaprenyl diphosphate synthase-like.
<p>In prokaryotes, undecaprenyl diphosphate synthase (UPP synthase, di-trans-poly-cis-decaprenylcistransferase or ditrans,polycis-undecaprenyl-diphosphate synthase ([ec:2.5.1.31])), catalyzes the formation of the carrier lipid undecaprenyl pyrophosphate (UPP) in bacterial cell wall peptidoglycan biosynthesis from isopentenyl pyrophosphate (IPP) [[cite:PUB00002321], [cite:PUB00003021], [cite:PUB00079916], [cite:PUB00079917], [cite:PUB00079918], [cite:PUB00079919], [cite:PUB00079920], [cite:PUB00079921], [cite:PUB00079922], [cite:PUB00079923], [cite:PUB00079926], [cite:PUB00079927], [cite:PUB00010618], [cite:PUB00079928]]. Cis (Z)-Isoprenyl diphosphate synthase (cis-IPPS) catalyzes the successive 1'-4 condensation of the IPP molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg<sup>2+</sup>for activity. Homologues are also found in archaebacteria and include a number of uncharacterised proteins including some from yeasts.</p> <p>This entry also matches related enzymes that transfer alkyl groups, such as dehydrodolichyl diphosphate synthase from eukaryotes, which catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | Transferase activity, transferring alkyl or aryl (other than methyl) groups | Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor). |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Undecaprenyl pyrophosphate synthetase [Medicago truncatula] gi|357443329|ref|XP_003591942.1| | 10 | ||
– | Nogo-B receptor [Medicago truncatula] gi|357481057|ref|XP_003610814.1| | 5 | ||
– | PREDICTED: nogo-B receptor-like [Glycine max] gi|356538453|ref|XP_003537718.1| | 5 | ||
– | PREDICTED: nogo-B receptor-like [Cicer arietinum] gi|502159159|ref|XP_004511413.1| | 9 | ||
– | PREDICTED: dehydrodolichyl diphosphate synthase 2-like [Glycine max] gi|356553066|ref|XP_003544879.1| | 8 | ||
– | Nogo-B receptor [Medicago truncatula] gi|357481057|ref|XP_003610814.1| | 5 | ||
– | Alkyl transferase; TAIR: AT5G58770.1 Undecaprenyl pyrophosphate synthetase family protein; Swiss-Prot: sp|Q56Y11|DDPS2_ARATH Dehydrodolichyl diphosphate synthase 2; TrEMBL-Plants: tr|I1MBA3|I1MBA3_SOYBN Alkyl transferase; Found in the gene: LotjaGi1g1v0121200 | 12 | ||
– | Alkyl transferase; TAIR: AT5G58770.1 Undecaprenyl pyrophosphate synthetase family protein; Swiss-Prot: sp|Q56Y11|DDPS2_ARATH Dehydrodolichyl diphosphate synthase 2; TrEMBL-Plants: tr|I1MBA3|I1MBA3_SOYBN Alkyl transferase; Found in the gene: LotjaGi1g1v0121200 | 11 | ||
– | Alkyl transferase; TAIR: AT5G58770.1 Undecaprenyl pyrophosphate synthetase family protein; Swiss-Prot: sp|Q56Y11|DDPS2_ARATH Dehydrodolichyl diphosphate synthase 2; TrEMBL-Plants: tr|A0A0L9VPG9|A0A0L9VPG9_PHAAN Alkyl transferase; Found in the gene: LotjaGi1g1v0121300 | 17 | ||
– | Alkyl transferase; TAIR: AT2G17570.1 Undecaprenyl pyrophosphate synthetase family protein; Swiss-Prot: sp|Q8S2T1|DDPS6_ARATH Dehydrodolichyl diphosphate synthase 6; TrEMBL-Plants: tr|G7I9J6|G7I9J6_MEDTR Alkyl transferase; Found in the gene: LotjaGi4g1v0136300 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd00475 | CDD | 1 | 10.00 |