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IPR001441

Description

IPR001441 is a Decaprenyl diphosphate synthase-like.

<p>In prokaryotes, undecaprenyl diphosphate synthase (UPP synthase, di-trans-poly-cis-decaprenylcistransferase or ditrans,polycis-undecaprenyl-diphosphate synthase ([ec:2.5.1.31])), catalyzes the formation of the carrier lipid undecaprenyl pyrophosphate (UPP) in bacterial cell wall peptidoglycan biosynthesis from isopentenyl pyrophosphate (IPP) [[cite:PUB00002321], [cite:PUB00003021], [cite:PUB00079916], [cite:PUB00079917], [cite:PUB00079918], [cite:PUB00079919], [cite:PUB00079920], [cite:PUB00079921], [cite:PUB00079922], [cite:PUB00079923], [cite:PUB00079926], [cite:PUB00079927], [cite:PUB00010618], [cite:PUB00079928]]. Cis (Z)-Isoprenyl diphosphate synthase (cis-IPPS) catalyzes the successive 1'-4 condensation of the IPP molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg<sup>2+</sup>for activity. Homologues are also found in archaebacteria and include a number of uncharacterised proteins including some from yeasts.</p> <p>This entry also matches related enzymes that transfer alkyl groups, such as dehydrodolichyl diphosphate synthase from eukaryotes, which catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Transferase activity, transferring alkyl or aryl (other than methyl) groups Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).

Associated Lotus transcripts 10

Transcript Name Description Predicted domains Domain count
Undecaprenyl pyrophosphate synthetase [Medicago truncatula] gi|357443329|ref|XP_003591942.1| 10
Nogo-B receptor [Medicago truncatula] gi|357481057|ref|XP_003610814.1| 5
PREDICTED: nogo-B receptor-like [Glycine max] gi|356538453|ref|XP_003537718.1| 5
PREDICTED: nogo-B receptor-like [Cicer arietinum] gi|502159159|ref|XP_004511413.1| 9
PREDICTED: dehydrodolichyl diphosphate synthase 2-like [Glycine max] gi|356553066|ref|XP_003544879.1| 8
Nogo-B receptor [Medicago truncatula] gi|357481057|ref|XP_003610814.1| 5
Alkyl transferase; TAIR: AT5G58770.1 Undecaprenyl pyrophosphate synthetase family protein; Swiss-Prot: sp|Q56Y11|DDPS2_ARATH Dehydrodolichyl diphosphate synthase 2; TrEMBL-Plants: tr|I1MBA3|I1MBA3_SOYBN Alkyl transferase; Found in the gene: LotjaGi1g1v0121200 12
Alkyl transferase; TAIR: AT5G58770.1 Undecaprenyl pyrophosphate synthetase family protein; Swiss-Prot: sp|Q56Y11|DDPS2_ARATH Dehydrodolichyl diphosphate synthase 2; TrEMBL-Plants: tr|I1MBA3|I1MBA3_SOYBN Alkyl transferase; Found in the gene: LotjaGi1g1v0121200 11
Alkyl transferase; TAIR: AT5G58770.1 Undecaprenyl pyrophosphate synthetase family protein; Swiss-Prot: sp|Q56Y11|DDPS2_ARATH Dehydrodolichyl diphosphate synthase 2; TrEMBL-Plants: tr|A0A0L9VPG9|A0A0L9VPG9_PHAAN Alkyl transferase; Found in the gene: LotjaGi1g1v0121300 17
Alkyl transferase; TAIR: AT2G17570.1 Undecaprenyl pyrophosphate synthetase family protein; Swiss-Prot: sp|Q8S2T1|DDPS6_ARATH Dehydrodolichyl diphosphate synthase 6; TrEMBL-Plants: tr|G7I9J6|G7I9J6_MEDTR Alkyl transferase; Found in the gene: LotjaGi4g1v0136300 12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00475 CDD 1 10.00