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IPR004360

Source: InterPro

Description

IPR004360 is a Glyoxalase/fosfomycin resistance/dioxygenase domain.

<p>Glyoxalase I ([ec:4.4.1.5]) (lactoylglutathione lyase) catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid [[cite:PUB00002779]]. Glyoxalase I is an ubiquitous enzyme which binds one mole of zinc per subunit. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric. The sequence of glyoxalase I is well conserved.</p> <p>The domain represented by this entry is found in glyoxalase I and in other related proteins, including fosfomycin resistance proteins FosB [[cite:PUB00053914]], FosA [[cite:PUB00055578]], FosX [[cite:PUB00043234]] and dioxygenases (eg. 4-hydroxyphenylpyruvate dioxygenase).</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 46

Transcript Name Description Predicted domains Domain count
Lj0g3v0262729.1
– Lactoylglutathione lyase / glyoxalase I family protein [Theobroma cacao] gi|508779235|gb|EOY26491.1|
Domains
8
Lj0g3v0278319.1
– Lactoylglutathione lyase / glyoxalase I family protein [Theobroma cacao] gi|508699005|gb|EOX90901.1|
Domains
8
Lj1g3v0084940.1
– Lactoylglutathione lyase [Medicago truncatula] gi|357480883|ref|XP_003610727.1|
Domains
8
Lj1g3v2065440.1
– PREDICTED: probable lactoylglutathione lyase, chloroplast-like [Glycine max] gi|356507913|ref|XP_003522707.1|
Domains
19
Lj2g3v0834820.1
– PREDICTED: probable lactoylglutathione lyase, chloroplast-like [Glycine max] gi|356529638|ref|XP_003533396.1|
Domains
12
Lj2g3v1717620.1
– Lactoylglutathione lyase [Medicago truncatula] gi|357483689|ref|XP_003612131.1|
Domains
8
Lj3g3v2212500.1
– PREDICTED: metallothiol transferase FosB-like [Fragaria vesca subsp]. vesca] gi|470134255|ref|XP_004302970.1|
Domains
8
Lj3g3v2212500.2
– PREDICTED: metallothiol transferase FosB-like [Fragaria vesca subsp]. vesca] gi|470134255|ref|XP_004302970.1|
Domains
7
Lj3g3v3054580.1
– PREDICTED: lactoylglutathione lyase-like [Glycine max] gi|356542658|ref|XP_003539783.1|
Domains
13
Lj4g3v0149470.1
– Lactoylglutathione lyase [Medicago truncatula] gi|357480323|ref|XP_003610447.1|
Domains
12
Lj4g3v2172940.1
– Lactoylglutathione lyase / glyoxalase I family protein [Theobroma cacao] gi|508783121|gb|EOY30377.1|
Domains
8
Lj4g3v2172940.2
– Lactoylglutathione lyase / glyoxalase I family protein [Theobroma cacao] gi|508783121|gb|EOY30377.1|
Domains
8
Lj4g3v3002440.1
– Lactoylglutathione lyase / glyoxalase I family protein [Theobroma cacao] gi|508777654|gb|EOY24910.1|
Domains
7
Lj4g3v3058250.1
– PREDICTED: probable lactoylglutathione lyase, chloroplast-like isoform X2 [Cicer arietinum] gi|502138585|ref|XP_004503462.1|
Domains
14
Lj4g3v3058250.2
– PREDICTED: probable lactoylglutathione lyase, chloroplast-like isoform X1 [Cicer arietinum] gi|502138583|ref|XP_004503461.1|
Domains
13
Lj6g3v1873580.1
– Lactoylglutathione lyase [Gossypium hirsutum] gi|211906514|gb|ACJ11750.1|
Domains
12
Lj6g3v1873580.2
– Lactoylglutathione lyase [Gossypium hirsutum] gi|211906514|gb|ACJ11750.1|
Domains
12
LotjaGi1g1v0044100.1
– 4-hydroxyphenylpyruvate dioxygenase; TAIR: AT1G06570.1 4-hydroxyphenylpyruvate dioxygenase; Swiss-Prot: sp|P93836|HPPD_ARATH 4-hydroxyphenylpyruvate dioxygenase; TrEMBL-Plants: tr|A0A0L9UUC5|A0A0L9UUC5_PHAAN 4-hydroxyphenylpyruvate dioxygenase; Found in the gene: LotjaGi1g1v0044100
Domains
15
LotjaGi1g1v0404100.1
– Lactoylglutathione lyase; TAIR: AT1G67280.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein; Swiss-Prot: sp|Q8W593|LGUC_ARATH Probable lactoylglutathione lyase, chloroplastic; TrEMBL-Plants: tr|I1JUU8|I1JUU8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0404100
Domains
20
LotjaGi2g1v0221400.1
– Lactoylglutathione lyase-like protein; TAIR: AT1G67280.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein; Swiss-Prot: sp|Q8W593|LGUC_ARATH Probable lactoylglutathione lyase, chloroplastic; TrEMBL-Plants: tr|I1L4L5|I1L4L5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0221400
Domains
15
LotjaGi2g1v0383600.1
– Lactoylglutathione lyase; TAIR: AT1G15380.1 Lactoylglutathione lyase / glyoxalase I family protein; Swiss-Prot: sp|Q65KJ5|FOSB_BACLD Metallothiol transferase FosB; TrEMBL-Plants: tr|T2DPS9|T2DPS9_PHAVU Lactoylglutathione lyase; Found in the gene: LotjaGi2g1v0383600
Domains
10
LotjaGi2g1v0455200.1
– Lactoylglutathione lyase/glyoxalase I family protein; TAIR: AT2G32090.1 Lactoylglutathione lyase / glyoxalase I family protein; Swiss-Prot: sp|Q09751|LGUL_SCHPO Lactoylglutathione lyase; TrEMBL-Plants: tr|I3S2T1|I3S2T1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0455200
Domains
9
LotjaGi3g1v0010800.1
– Metallothiol transferase fosB; TAIR: AT1G80160.3 Lactoylglutathione lyase / glyoxalase I family protein; Swiss-Prot: sp|A4IS40|FOSB_GEOTN Metallothiol transferase FosB; TrEMBL-Plants: tr|B9RV37|B9RV37_RICCO Lactoylglutathione lyase, putative; Found in the gene: LotjaGi3g1v0010800
Domains
10
LotjaGi3g1v0358200.1
– Lactoylglutathione lyase/glyoxalase I family protein; TAIR: AT1G80160.3 Lactoylglutathione lyase / glyoxalase I family protein; Swiss-Prot: sp|Q65KJ5|FOSB_BACLD Metallothiol transferase FosB; TrEMBL-Plants: tr|I3TAB9|I3TAB9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0358200
Domains
10
LotjaGi3g1v0486600.1
– Lactoylglutathione lyase; TAIR: AT1G08110.4 lactoylglutathione lyase family protein / glyoxalase I family protein; Swiss-Prot: sp|Q9ZS21|LGUL_SOYBN Lactoylglutathione lyase; TrEMBL-Plants: tr|V7AGB4|V7AGB4_PHAVU Lactoylglutathione lyase; Found in the gene: LotjaGi3g1v0486600
Domains
15
LotjaGi3g1v0486600.2
– Lactoylglutathione lyase; TAIR: AT1G08110.1 lactoylglutathione lyase family protein / glyoxalase I family protein; Swiss-Prot: sp|Q9ZS21|LGUL_SOYBN Lactoylglutathione lyase; TrEMBL-Plants: tr|I3T0P3|I3T0P3_LOTJA Lactoylglutathione lyase; Found in the gene: LotjaGi3g1v0486600
Domains
16
LotjaGi3g1v0486600.3
– Lactoylglutathione lyase; TAIR: AT1G08110.4 lactoylglutathione lyase family protein / glyoxalase I family protein; Swiss-Prot: sp|Q9ZS21|LGUL_SOYBN Lactoylglutathione lyase; TrEMBL-Plants: tr|I1LL14|I1LL14_SOYBN Lactoylglutathione lyase; Found in the gene: LotjaGi3g1v0486600
Domains
15
LotjaGi3g1v0547200.1
– Lactoylglutathione lyase; TAIR: AT2G28420.1 Lactoylglutathione lyase / glyoxalase I family protein; Swiss-Prot: sp|P16635|LGUL_PSEPU Lactoylglutathione lyase; TrEMBL-Plants: tr|A0A151TLQ2|A0A151TLQ2_CAJCA Lactoylglutathione lyase; Found in the gene: LotjaGi3g1v0547200
Domains
12
LotjaGi4g1v0013800.1
– Lactoylglutathione lyase; TAIR: AT1G11840.6 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; Swiss-Prot: sp|Q39366|LGUL_BRAOG Putative lactoylglutathione lyase; TrEMBL-Plants: tr|A0A151SU07|A0A151SU07_CAJCA Putative lactoylglutathione lyase; Found in the gene: LotjaGi4g1v0013800
Domains
15
LotjaGi4g1v0013800.2
– Lactoylglutathione lyase; TAIR: AT1G11840.6 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; Swiss-Prot: sp|Q39366|LGUL_BRAOG Putative lactoylglutathione lyase; TrEMBL-Plants: tr|I1KNE1|I1KNE1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0013800
Domains
15
LotjaGi4g1v0013800.3
– Lactoylglutathione lyase; TAIR: AT1G11840.6 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; Swiss-Prot: sp|Q39366|LGUL_BRAOG Putative lactoylglutathione lyase; TrEMBL-Plants: tr|I1KNE1|I1KNE1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0013800
Domains
15
LotjaGi4g1v0125900.1
– Lactoylglutathione lyase; TAIR: AT1G15380.1 Lactoylglutathione lyase / glyoxalase I family protein; Swiss-Prot: sp|Q9CPU0|LGUL_MOUSE Lactoylglutathione lyase; TrEMBL-Plants: tr|I3SFD9|I3SFD9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0125900
Domains
10
LotjaGi4g1v0125900.2
– Lactoylglutathione lyase; TAIR: AT1G15380.1 Lactoylglutathione lyase / glyoxalase I family protein; Swiss-Prot: sp|Q9CPU0|LGUL_MOUSE Lactoylglutathione lyase; TrEMBL-Plants: tr|I3SFD9|I3SFD9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0125900
Domains
10
LotjaGi4g1v0125900.3
– Lactoylglutathione lyase; TAIR: AT1G15380.1 Lactoylglutathione lyase / glyoxalase I family protein; Swiss-Prot: sp|Q9CPU0|LGUL_MOUSE Lactoylglutathione lyase; TrEMBL-Plants: tr|I3SFD9|I3SFD9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0125900
Domains
10
LotjaGi4g1v0269400.1
– Lactoylglutathione lyase/glyoxalase I family protein; TAIR: AT1G80160.1 Lactoylglutathione lyase / glyoxalase I family protein; Swiss-Prot: sp|A4IS40|FOSB_GEOTN Metallothiol transferase FosB; TrEMBL-Plants: tr|I3SBX8|I3SBX8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0269400
Domains
11
LotjaGi4g1v0311600.1
– Lactoylglutathione lyase / glyoxalase I family protein; TAIR: AT5G57040.1 Lactoylglutathione lyase / glyoxalase I family protein; Swiss-Prot: sp|P45871|YWKD_BACSU Uncharacterized protein YwkD; TrEMBL-Plants: tr|I3S2W6|I3S2W6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0311600
Domains
10
LotjaGi4g1v0447100.1
– Lactoylglutathione lyase; TAIR: AT1G67280.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein; Swiss-Prot: sp|Q8W593|LGUC_ARATH Probable lactoylglutathione lyase, chloroplastic; TrEMBL-Plants: tr|I3TAJ8|I3TAJ8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0447100
Domains
15
LotjaGi4g1v0447100.2
– Lactoylglutathione lyase; TAIR: AT1G67280.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein; Swiss-Prot: sp|Q8W593|LGUC_ARATH Probable lactoylglutathione lyase, chloroplastic; TrEMBL-Plants: tr|I3TAJ8|I3TAJ8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0447100
Domains
15
LotjaGi4g1v0447100.3
– Lactoylglutathione lyase; TAIR: AT1G67280.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein; Swiss-Prot: sp|Q8W593|LGUC_ARATH Probable lactoylglutathione lyase, chloroplastic; TrEMBL-Plants: tr|I3TAJ8|I3TAJ8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0447100
Domains
14
LotjaGi4g1v0447100.4
– Lactoylglutathione lyase; TAIR: AT1G67280.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein; Swiss-Prot: sp|Q8W593|LGUC_ARATH Probable lactoylglutathione lyase, chloroplastic; TrEMBL-Plants: tr|I3TAJ8|I3TAJ8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0447100
Domains
14
LotjaGi6g1v0294200.1
– Lactoylglutathione lyase; TAIR: AT1G11840.6 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; Swiss-Prot: sp|Q39366|LGUL_BRAOG Putative lactoylglutathione lyase; TrEMBL-Plants: tr|I3T6L8|I3T6L8_LOTJA Lactoylglutathione lyase; Found in the gene: LotjaGi6g1v0294200
Domains
15
LotjaGi6g1v0294200.2
– Lactoylglutathione lyase; TAIR: AT1G11840.6 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; Swiss-Prot: sp|Q39366|LGUL_BRAOG Putative lactoylglutathione lyase; TrEMBL-Plants: tr|I3T6L8|I3T6L8_LOTJA Lactoylglutathione lyase; Found in the gene: LotjaGi6g1v0294200
Domains
15
LotjaGi6g1v0294200.3
– Lactoylglutathione lyase; TAIR: AT1G11840.6 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; Swiss-Prot: sp|Q39366|LGUL_BRAOG Putative lactoylglutathione lyase; TrEMBL-Plants: tr|I3T6L8|I3T6L8_LOTJA Lactoylglutathione lyase; Found in the gene: LotjaGi6g1v0294200
Domains
15
LotjaGi6g1v0294200.4
– Lactoylglutathione lyase; TAIR: AT1G11840.6 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; Swiss-Prot: sp|Q39366|LGUL_BRAOG Putative lactoylglutathione lyase; TrEMBL-Plants: tr|I3T6L8|I3T6L8_LOTJA Lactoylglutathione lyase; Found in the gene: LotjaGi6g1v0294200
Domains
15
LotjaGi6g1v0294200.5
– Lactoylglutathione lyase; TAIR: AT1G11840.6 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; Swiss-Prot: sp|Q39366|LGUL_BRAOG Putative lactoylglutathione lyase; TrEMBL-Plants: tr|I3T6L8|I3T6L8_LOTJA Lactoylglutathione lyase; Found in the gene: LotjaGi6g1v0294200
Domains
15
LotjaGi6g1v0294200.6
– Lactoylglutathione lyase; TAIR: AT1G11840.6 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; Swiss-Prot: sp|Q39366|LGUL_BRAOG Putative lactoylglutathione lyase; TrEMBL-Plants: tr|I3T6L8|I3T6L8_LOTJA Lactoylglutathione lyase; Found in the gene: LotjaGi6g1v0294200
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd16358 CDD 1 2.17