Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR004538

Source: InterPro

Description

IPR004538 is a Hemolysin A /rRNA methyltransferase TlyA.

<p>Haemolysins are exotoxins that attack blood cell membranes and cause cell rupture. The mechanism of action is not well defined. Hemolysin A is induced by sodium ribonucleate, and is produced by pathogenic bacterial strains. Haemolysin A from Treponema hyodysenteriae causes swine dysentery [[cite:PUB00043014]]. The homologous protein from Mycobacterium tuberculosis is known as 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA and exhibits haemolytic activity in vitro. It catalyses the 2'-O-methylation at nucleotides C1409 in 16S rRNA and C1920 in 23S rRNA [[cite:PUB00043015], [cite:PUB00059301], [cite:PUB00059302]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003723
Molecular function RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi3g1v0076100.1
– Ribosomal RNA large subunit methyltransferase J; TAIR: AT3G25470.1 bacterial hemolysin-like protein; Swiss-Prot: sp|P19672|YQXC_BACSU Putative rRNA methyltransferase YqxC; TrEMBL-Plants: tr|K7KE27|K7KE27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0076100
Domains
18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd02440 CDD 1 100.00