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IPR004613

Description

IPR004613 is a Ribonuclease J.

<p>This family of proteins are about 50 to 77kDa. The central region is well conserved and contains three conserved histidines. Most of these proteins are related at the N-terminal region to the beta-lactamase family. The family has been characterised as ribonuclease J. RNase J cleaves the 5'-leader sequence of certain mRNAs and may play a role in the maturation and stability of specific mRNAs [[cite:PUB00074172]]. It is also required for the maturation of the 16S rRNA acting preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal subunits [[cite:PUB00074173], [cite:PUB00074174]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
Molecular function Metal ion binding Interacting selectively and non-covalently with any metal ion.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
PREDICTED: ribonuclease J-like isoform X1 [Cicer arietinum] gi|502130444|ref|XP_004500652.1| 17
PREDICTED: ribonuclease J-like isoform X2 [Cicer arietinum] gi|502130447|ref|XP_004500653.1| 14

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00